Derya İLEM ÖZDEMİR
Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü, Radyofarmasi Anabilim Dalı
Araştırma alanları: Sağlık Bilimleri, Eczacılık, Eczacılık Teknolojisi, Radyofarmasi, Farmasötik Teknoloji, Temel Bilimler, Meslek Bilimleri, Kimya, Biyokimya, Temel Eczacılık Bilimleri
<p>Lisans öğrenimini 2005 yılında Ege Üniversitesi Eczacılık Fakültesinde tamamlamış, 2006 yılında Radyofarmasi Anabilim Dalı’na “Araştırma Görevlisi” olarak atanmıştır. Ege Üniversitesi Sağlık Bilimleri Enstitüsü Radyofarmasi Programında 2008 yılında yüksek lisans, 2012 yılında Doktora öğrenimini tamamlamıştır. 2013 yılında “Yardımcı Doçent”, 2017 yılında “Doçent”, 2024 yılında "Profesör" unvanlarını almıştır.</p><p>2009 yılında, Queen Mary Üniversitsitesi Londra’da radyofarmasi departmanında konuk araştırmacı olarak görev yapmıştır. Görevi süresince GMP koşullarında radyofarmasötik üretiminde, radyofarmasötiklerin kalite kontrollerinde çalışmış aynı zamanda kanser araştırma merkezinde araştırmalar yürütmüştür. Paris ve Slovenya’da EANM tarafından düzenlenen "postgraduate radyofarmacy" kurslarını başarıyla tamamlamıştır. </p><p>Ulusal ve Uluslararası çeşitli kurumlar tarafından desteklenen 30’un üzerinde projede yürütücü ve araştırıcı olarak çalışmıştır. Uluslararası ve ulusal çeşitli bilimsel etkinliklerin bilim ve düzenleme komitesinde görev almış, konferanslara katılmış, yüksek lisans ve doktora tez yöneticiliğinin yanı sıra çeşitli ulusal ve uluslararası bilimsel dergilerde hakemlik ve editörlük yapmıştır.</p><p>2018-2022 yılları arasında Ege Üniversitesi Eczacılık Fakültesi Dekan Yardımcılığı ve Radyofarmasi Anabilim Dalı Başkanlığı görevlerini sürdürmüştür. Türk Farmakopesi Radyofarmasötikler bölümü yazarlarındandır. Lisans ve lisansüstü düzeyde Radyofarmasi alanında çeşitli dersler vermektedir. Akademik ve bilimsel danışman olarak çeşitli kurul ve komisyonlarda görev almaktadır.</p><p>Yeni radyofarmasötiklerin tasarlanması, Nanoradyofarmasötikler, Moleküler Tanı/Tedavi, Teranostikler konularındaki bilimsel çalışmalarını sürdürmekte ileri derecede İngilizce bilmektedir.</p>
Yayınlar
- Radiolabeled 5-Fluorouracil-Loaded Solid Lipid Nanoparticles: A Potential Platform for Colorectal Cancer Imaging (2026)
- IGF2R-Targeted Alpha Therapy of Osteosarcoma Enabled by Conjugated [ 225 Ac]Ac-Macropa-PEG 4 -IF3 (2026)
- Technetium-99m Radiolabeled Carboplatin Polymeric Nanoparticles for Imaging and Treatment of Epithelial Ovarian Cancer (2026)
- Comparative Evaluation of Release Profiles from Hydrogel, Oleogel, and Bigel Systems Containing Model Radiopharmaceuticals for Buccal Delivery (2025)
- Targeting TROP-2 in Prostate Cancer Using Site-Specifically Radiolabeled IMMU-132 with ⁸⁹Zr via 3,4,3-LI(1,2-HOPO) (2025)
- Radiosynthesis and Preclinical Evaluation of [89Zr]Zr-3,4,3-LI(1,2-HOPO)-Durvalumab for Immuno-PET (2025)
- Synthesis and Preclinical Evaluation of 99 ᵐTc‐HYNIC–Finasteride: A Novel SPECT Radiotracer Targeting 5α‐Reductase in Prostate Cancer (2025)
- Synthesis and evaluation of [99mTc]Tc–octapa–necitumumab for targeted imaging of squamous non-small cell lung cancer (2025)
- Preparation, Optimization, and Stability of Isosulfan Blue-Loaded Human Serum Albumin-Structured Nanocolloids (2025)
- Radiolabelling and cellular binding studies of metformin and indomethacin loaded dual niosome formulations on human colorectal adenocarcinoma cell line (2025)
- Nanostructured Lipoxin A4: Understanding Its Biological Behavior and Impact on Alzheimer’s Disease (Proof of Concept) (2025)
- Radiolabeling and quality control studies of [99mTc] Tc-dexketoprofen trometamol for inflammation imaging (2025)
- Comparative Evaluation of Release Profiles from Hydrogel, Oleogel, and Bigel Systems Containing Model Radiopharmaceuticals for Buccal Delivery (2025)
- Radiolabelling and cellular binding studies of metformin and indomethacin loaded dual niosome formulations on human colorectal adenocarcinoma cell line (2025)
- Radiolabeling and quality control studies of [99mTc]Tc-dexketoprofen trometamol for inflammation imaging (2025)
- Can radiopharmaceuticals be delivered by quantum dots? (2024)
- Micellar solution of [223Ra]RaCl2: Reaching renal excretion, potent efficacy in osteoblastic osteosarcoma in PDX model, biochemistry alterations and pharmacokinetics (2024)
- Molecular Imaging for Lung Cancer: Exploring Small Molecules, Peptides, and Beyond in Radiolabeled Diagnostics (2024)
- Nano-hydroxyapatite radiolabeled with radium dichloride [223Ra] RaCl2 for bone cancer targeted alpha therapy: In vitro assay and radiation effect on the nanostructure (2023)
- MONOCLONAL ANTIBODIES USED IN CANCER DIAGNOSIS AND TREATMENT (2023)
- Radiolabeled Human Serum Albumin Nanoparticles Co-Loaded with Methotrexate and Decorated with Trastuzumab for Breast Cancer Diagnosis (2023)
- Radiolabeling and Cell Incorporatıon Studies of Indomethacin and Metformin Loaded Dual Niosome Formulations (2023)
- [99mTc]Technetium-Labeled Niosomes: Radiolabeling, Quality Control, and In Vitro Evaluation (2023)
- KANSER TANISI VE TEDAVİSİNDE KULLANILAN MONOKLONAL ANTİKORLAR (2023)
- Radiolabeling, quality control and in vitro evaluation of [99mTc]TcHMPAO-exosomes for wound healing (2023)
- FORMULATION AND CHARACTERIZATION OF INDOMETHACIN AND METFORMIN LOADED DUAL NIOSOME (2023)
- RADIOLABELING AND CELL INCORPORATION STUDIES OF INDOMETHACIN AND METFORMIN LOADED DUAL NIOSOME FORMULATIONS (2023)
- A preliminary study on radiolabeling and quality control of [99mTc]Tc-6-mercaptopurine to develop tumor scintigraphic agent (2023)
- Radiolabeled gemcitabine hydrochloride as an imaging agent for lung cancer: Radiolabeling, quality control and cell incorporation studies (2023)
- Exploiting the extemporaneousness of radiopharmaceuticals: Radiolabeling stability under diverse conditions (2022)
- Preparation, radiolabeling and cell culture studies of chitosan coated PLGA nanoparticles as a potential cancer diagnostic agent (2022)
- QUALITY ASSURANCE AND QUALITY CONTROL OF RADIOPHARMACEUTICALS: AN OVERVIEW (2022)
- CELL INCORPORATION STUDY OF [<sup>99m</sup>Tc]Tc-NAB-PACLITAXEL ON HUMAN COLORECTAL ADENOCARCINOMA CELL LINE (2022)
- Radiolabeling, Quality Control, and Cell Binding Studies of New 99mTc-Labeled Bisphosphonates: 99mTc-Ibandronate Sodium (2022)
- Biodistribution of 99mTc-PLA/PVA/Atezolizumab nanoparticles for non-small cell lung cancer diagnosis (2022)
- HEDEFE YÖNELİK TEDAVİDE GÜNCEL YAKLAŞIMLAR: LUTESYUM-177 İLE İŞARETLİ RADYOFARMASÖTİKLER (2022)
- Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology (2022)
- Development and validation of UV/VIS spectroscopy method for determination of atezolizumab in pharmaceutical products (2022)
- 99mTc-exendin-4: Radiolabeling and quality control studies of glucagon-like peptide analog (2022)
- Development and validation of UV/VIS spectroscopy method for determination of atezolizumab in pharmaceutical products (2022)
- The use of Lamivudine-loaded PLGA nanoparticles in the diagnosis of lung cancer: Preparation, characterization, radiolabeling with 99mTc and cell binding (2022)
- Preparation and Evaluation of Poly(lactic acid)/Poly(vinyl alcohol) Nanoparticles Using the Quality by Design Approach (2022)
- Folic acid-functionalized graphene quantum dots: Synthesis, characterization, radiolabeling with radium-223 and antiviral effect against Zika virus infection (2022)
- Atezolizumab-Conjugated Poly(lactic acid)/Poly(vinyl alcohol) Nanoparticles as Pharmaceutical Part Candidates for Radiopharmaceuticals (2022)
- Radiolabeled methotrexate loaded chitosan nanoparticles as imaging probe for breast cancer: Biodistribution in tumor-bearing mice (2022)
- Theranostic Applications in Nuclear Medicine: Traditional Review (2022)
- An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies (2022)
- The Effects of Combination Therapy of Ionizing Radiation and Oncolytic Viruses (2021)
- İyonlaştırıcı Radyasyon ve Onkolitik Virüsler ile Kombine Tedavinin Etkileri (2021)
- İyonlaştırıcı Radyasyon ve Onkolitik Virüsler ile Kombine Tedavinin Etkileri (2021)
- Radiopharmaceuticals Used in Molecular Imaging (2021)
- NANOTHERANOSTICS (2021)
- Radyofarmasötikler ve Teranostikler (2021)
- Development and radiolabeling of lipid nanoparticles with [99mTc]Tc-HMPAO: Characterization, stability, cytotoxicity and cell binding studies (2021)
- Current Approaches in Nanomedicine (2020)
- The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells (2020)
- The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells (2020)
- Preparation, Characterization and Cell Binding Studies for Newly Developed Radiopharmaceutical: [99mTc]Tc-HMPAO Lipid Nanoparticles (2020)
- Recent developments in cancer therapy and diagnosis (2020)
- Radyasyon ve İnsan Sağlığı Üzerindeki Etkileri (2020)
- Nanobioradiopharmaceuticals (2019)
- Evaluation of cytotoxic effects of nanostructured drug delivery systems containing different lipid derivatives on MRC-5 and Hela cells (2019)
- Computational Study of Radiopharmaceuticals (2019)
- Nuclear medicine and radiopharmaceuticals for molecular diagnosis (2019)
- Preformulation of nanostructured lipid carrier system for targeting on gastrointestinal stromal tumours (2019)
- Nuclear medicine and radiopharmaceuticals for molecular diagnosis (2019)
- Nuclear medicine and radiopharmaceuticals for molecular diagnosis (2019)
- Computational Study of Radiopharmaceuticals (2019)
- Human serum albumin based nanoparticle preparation via nanoprecipitation method (2019)
- Nanoradiopharmaceuticals (2019)
- In Vitro Evaluation of Technetium-99m Labeled Nanostructured Lipid Carrier Systems Containing Imatinib Mesylate (2019)
- EVALUATION OF CYTOTOXIC EFFECTS OFNANOSTRUCTURED DRUG DELIVERY SYSTEMSCONTAINING DIFFERENT LIPID DERİVATIVES ON MRC-5AND HELA CELLS (2019)
- Radiolabeling of new nanostructured lipid carrier system with technetium-99m (2019)
- Preparation and Characterization of Nanostructured Lipid Carrier Systems for Solubility and Dissolution of Imatinib Mesylate (2019)
- Cell Treatment Capacity of Nanostructured Lipid Carrier Containing Imatinib Mesylate (2019)
- Preparation and Characterization of Nanostructured Lipid Carrier Systems (NLCS) for Solubility and Dissolution of Imatinib Mesylate (2019)
- Radiolabeling and in vitro evaluation of a new 5-fluorouracil derivative with cell culture studies (2019)
- KONTRAST MADDELER (2019)
- Technetium-99m metastable radiochemistry for pharmaceutical applications: old chemistry for new products (2019)
- Technetium-99m radiolabeled glucagon-like peptide analog Exendin-4 for cancer diagnosis (2018)
- Gemcitabine hydrochloride microspheres used for intravesical treatment of superficial bladder cancer: a comprehensive in vitro/ex vivo/in vivo evaluation (2018)
- Radyofarmasi Araştırma ve Eğitim Laboratuvarlarının Lisanslanma Süreci (2018)
- Ege Üniversitesi Eczacılık Fakültesi Lisans Eğitimi Programı’nın EczÇEP’le ve Ulusal Standartlarla Uyumunu Geliştirme, Öğretim ve Değerlendirme Süreçlerini İyileştirme Projesi (2018)
- Ege Üniversitesi Eczacılık Fakültesi Eğitim Programı İyileştirme ve Geliştirme Projesi Kapsamında Yapılan Eczacılık Mesleği Görev Analizi Çalışması (2018)
- Türk Farmakopesi 2017 (2018)
- Radyofarmasi Ders Kitabı (2018)
- Recent Developments in Nuclear Medicine Applications of Radiolabeled Nanocarriers. (2018)
- Development and Evaluation of Liquid and Solid Lipid Based Drug Delivery Systems Containing Technetium-99m-Radiolabeled Alendronate Sodium (2018)
- Recent developments in nuclear medicine applications of radiolabeled nanocarriers (2018)
- Radiopharmaceuticals Used in Imaging and Treatment in Nuclear Medicine (2018)
- Recent developments in nuclear medicine applications of radiolabeled nanocarriers (2018)
- Radiopharmaceuticals Used in Imaging and Treatment in Nuclear Medicine (2018)
- Albumin-Based Nanoparticulate Drug Delivery Systems (2018)
- Targeting Strategies of Radiopharmaceuticals by UsingDrug Delivery Systems for Cancer Imaging (2018)
- Optimization the Preparation Process of Methotrexate Loaded Human Serum Albumin Nanoparticles (2018)
- Development and Evaluation of Liquid and Solid Lipid Based Drug Delivery Systems Containing Technetium-99m-Radiolabeled Alendronate Sodium. (2018)
- In loco retention effect of magnetic core mesoporous silica nanoparticles doped with trastuzumab as intralesional nanodrug for breast cancer (2018)
- Radioanalytical chromatography techniques for newly developed radiopharmaceutical: 99mTc-ibandronate sodium. (2018)
- Tc-99m Radiolabeled Alendronate Sodium Microemulsion: Characterization and Permeability Studies Across Caco-2 Cells (2018)
- Development and Evaluation of Lipid-Water Based Drug Delivery Systems Containing Technetium-99m-Radiolabeled Alendronate Sodium Prepared by Spray Drying Method (2018)