IGF2R-Targeted Alpha Therapy of Osteosarcoma Enabled by Conjugated [ 225 Ac]Ac-Macropa-PEG 4 -IF3
Makaleler > Tam Makale · 2026
Yazarlar: Syed Qaiser Shah, Ralph Santos-Oliveira, Derya İLEM ÖZDEMİR, Madeeha Shabnam
Bioconjugate Chemistry, Uluslararası, Wos, 2026, cilt 37, ss 1025-1034
DOI: 10.1021/acs.bioconjchem.6c00125
Özet
-IF3 is a translational orphan alpha therapeutic for osteosarcoma with excellent radiochemical stability and potency and low off-target toxicity.