Safiye EMİRDAĞ
Fen Fakültesi, Kimya Bölümü, Kimya Bölümü
Research areas: Natural Sciences, Chemistry, Organic Chemistry, Biochemistry, Chemistry of Natural Products, Plant Chemistry, Organic Spectroscopy, Organic Reaction Mechanisms, Bioorganic Chemistry, Life Sciences
Publications
- The utilisation of turpentine and moss oil as epoxy hardeners for bio-based epoxy nanocomposite coatings (2026)
- The utilisation of turpentine and moss oil as epoxy hardeners for bio-based epoxy nanocomposite coatings (2026)
- Synthesis and Biological Evaluation of New Thiocarbamoylpyrazoline and Chalcone Derivatives on Bone Cancer Cell Lines: In Vitro and In Silico Studies (2026)
- Investigation of biological activities and bioactive compounds of Rhynchostegium megapolitanum collected from Aydın, Türkiye (2026)
- Design, Synthesis, and Biological Evaluation of Methoxy-Substituted Chalcones and Gypsogenin-Based Hybrids as Anticancer and Antimicrobial Agents (2026)
- PLANT-DERIVED NATURAL PRODUCTS IN DRUG DISCOVERY: HISTORICAL INSIGHTS AND CONTEMPORARY APPLICATIONS (2025)
- Comparison of new hydrazone epoxy coatings and their nanocomposite derivatives (2025)
- Improving Surface Properties of Wood Material Against Weathering by Using New Bio-based Epoxy Nanocomposites (2025)
- ADME predictions and molecular docking insights for novel Gypsogenin–chalcone hybrids and chalcones as antitumor and antimicrobial agents (2025)
- Novel Semi-SyntheticDerivative from Gypsogenin Aglycone obtained Gypsophila Arrostii Roots (2024)
- Novel Semi-Synthetic Gypsogenin Derivative and Anticancer Activity Against Caco-2 Cancer Cell Line (2024)
- Synthesis of Novel N-Substituted-1,4-Naphthoquinone Derivatives (2024)
- Synthesis And Characterization of New Vitamine K3 Analogues (2024)
- The Major Compound From Water Extract of the Roots of Gypsophila Arrostii and New Semi-Synthesis Derivative (2024)
- Design, Synthesis and Biological Evaluation of Novel Gypsogenin Derivatives as Potential Anticancer and Antimicrobial Agents (2024)
- NATURAL PRODUCTS AND ACTİVİTY RELATIONSHIP – GYPSOGENIN FROM GYPSOPHILA ARROSTII ROOTS (2023)
- Anticancer and antimicrobial activities of a novel 4-nitrobenzohydrazone and the Cu(II), Ni(II), Co(II), and Mn(II) complexes (2023)
- A new hybrid ligand and its metal complexes from a natural plant ( Styrax officinalis ) bearing egonol, thiosemicarbazone and oxime units, and their anti‐cancer activities (2022)
- Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction (2022)
- New Bioactive Semi-Synthesis Gypsogenin Compounds (2022)
- The Synthesis and Characterization of N-Substituted Quinone Analogues (2022)
- New Bioactive Compounds from Semi-Synthesis on the Natural Product (Gypsogenin) (2022)
- Novel Bioactive Compound from Gypsogenin Aglycone (2022)
- EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy (2021)
- Gypsogenin Bileşiğinden Yeni Anhidrit Türevlerinin Sentezi (2020)
- Natural Products and New Bioactive Semi-Synthetic Derivatives from Plants (2020)
- New semi-synthetic gypsogenin compounds (2020)
- Synthesis Of Novel Gypsogenin Derivatives (2019)
- Semi-Synthesis of Bioactive Gypsogenin Derivatives (2019)
- New Gypsogenin-Amine Compounds (2019)
- Natural Compounds and Gypsogenin-Activity Relationship (2019)
- PHYTOCHEMISTRY AND FERTILITY ACTIVITY OF Chondrilla juncea L. (Asteraceae) (2019)
- New Bioactive Gypsogenin Compounds (2019)
- Pentacyclic triterpene derivatives with selective anti-proliferative effect against chronic myelogenous leukemia (2019)
- Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity (2019)
- Gypsogenin-Chalcone Hybrid Compounds (2018)
- The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities (2018)
- Synthesis of gypsogenin-chalcone compounds (2017)
- KINASE INHIBITORY ACTIVITY OF GYPSOGENIN DERIVATIVES (2017)
- Synthesis of Gypsogenin-Chalcone Hybrid Compounds (2017)
- Yeni Gypsogenin-Kalkon Hibrit Bileşiklerin Sentezi ve Antimikrobiyal Aktivite Çalışmaları (2017)
- Toxicity of Gypsogenin to MDA-MB-231, MCF-7 Breast Cancer Cells and PC-3 Prostate Cancer Cells (2017)
- New Gypsogenin-Chalcone Hybrid Compounds (2017)
- STRONG HYDROGEN BONDED SUPRAMOLECULAR ARCHITECTURE IN A CRYSTAL OF THE {3-[2-(1,3-BENZODIOXOL-5-YL)-7-METHOXY-1-BENZOFURAN-5-YL] PROPYL} DIETHYLAMINE CATION WITH THE HYDROGEN BONDED CHLORIDE HYDRATE ANION (HALIDES) ASSEMBLY: X-RAY STRUCTURE, DFT CALCULATIONS, HIRSHFELD SURFACE ANALYSIS (2017)
- Antiproliferative Activity of Gypsogenin Anhydride to Breast and Prostate Cancer Cells (2017)
- Phenolic content and potential anti-inflammatory effects of Myrtus communis L. products (2016)
- Effects of egonol that isolated from seeds of Styrax officinalis (L.) on lipid peroxidation and antioxidant defense system in human erythrocytes (2016)
- Effects of egonol that isolated from seeds of Styrax officinalis (L.) on lipid peroxidation and antioxidant defense system in human erythrocytes (2016)
- How preeclampsia affects oxidant status and antiinflammatory potential of breast milk? (2016)
- New Synthesis From Gpsogenin and Chalcone Compounds (2016)
- In vitro hypoxia effect on cancer stem cells (2016)
- Spectroscopic and biological studies of new mononuclear metal complexes of a bidentate NN and NO hydrazone–oxime ligand derived from egonol (2015)
- Çöven Kökü Özütünden Gypsogenin Bilesiginin İzolasyonu, Semi-Sentetik Yeni Türevlerinin Eldesi, Antimikrobiyal ve Sitotoksik Aktivite Çalısmaları (2014)
- Synthesis, antimicrobial and cytotoxic activities, and structure–activity relationships of gypsogenin derivatives against human cancer cells (2014)
- Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells (2014)
- Laccase-catalyzed reaction of 3-tert-butyl-1H-pyrazol-5(4H)-one with substituted catechols using air as an oxidant (2013)
- Synthesis, characterization and in vitro anti-neoplastic activity of gypsogenin derivatives (2013)
- Effects of the Egonol on antioxidant defense system in rat liver (2012)
- Effects of the Egonol on some xenobiotic-metabolizing enzymes in rat live (2012)
- Doğal Benzofuran Egonol’den Yeni Türevlerin Sentezi (2011)
- Egonol ‘ün Rat Eritrosit Antioksidan Savunma Sistemi Üzerine Etkisi (2011)
- Helva Üretiminde Kullanılan Çöven Suyundan [Çöven Otu (Gypsophila arrostii)] gypsogenin’’ nin İzolasyonu, Saflandırılması ve Değişik Türevlerinin Sentezi (2010)
- Synthesis of egonol derivatives and their antimicrobial activities (2010)
- Synthesis of Some Benzofuran Derivatives and Their Activities (2009)
- Styrax officinalis L. Tohumlarından İzole Edilen Egonol’ün İnsan Eritrosit Antioksidan Enzimler ve Lipid Peroksidasyonu Üzerine Etkisi (2009)
- Styrax officinalis L. den İzole Edilen Egonol’den Yeni Bileşiklerin Sentezlenmesi ve Antibakterial Aktivitelerin İncelenmesi (2008)
- Synthesis and antibacterial activity of egonol derivatives (2008)
- Chemical Modifications on a Natural Product (egonol) Isolated from Styrax officinalis (2007)
- Synthesis and Biological Activity of Egonol Derivatives (2006)
- Triterpene Saponins from Knautia integrifolia var. bidens (2004)
- Triterpene Saponins from Knautia integrifolia var. bidens (2004)
- Triterpene Saponins from Knautia integrifolia var. bidens (2004)
- Knautia Integrifolia bitkisinden İki Yeni Triterpen Glikozit (2003)