Laccase-catalyzed reaction of 3-tert-butyl-1H-pyrazol-5(4H)-one with substituted catechols using air as an oxidant
Articles > Article · 2013
Authors: Safiye EMİRDAĞ, Szilvia HAJDOK, Juergen CONRAD, Uwe BEIFUSS
Tetrahedron, Journal Indexed in SCI Expanded, International, WoS, 2013, vol 69, pp 3664-3668
DOI: 10.1016/j.tet.2013.03.023
Summary
The laccase-catalyzed reaction of 3-tert-butyl-1H-pyrazol-5(4H)-one with a number of catechols and aerial oxygen as an oxidant selectively affords 4-substituted 3-tert-butyl-1H-pyrazol-5-ol derivatives with yields ranging from 77 to 99%. (C) 2013 Elsevier Ltd. All rights reserved.