Design, Synthesis, and Biological Evaluation of Methoxy-Substituted Chalcones and Gypsogenin-Based Hybrids as Anticancer and Antimicrobial Agents
Articles > Article · 2026
Authors: Nafia Gökçe Ulusoy, Safiye EMİRDAĞ, Nuran Kahriman, Fatma Demir, Vildan Serdaroğlu, Nurettin Yaylı, Burçin Türkmenoğlu
ACS Omega, International, WoS, 2026, vol 11, pp 25537-25551
Summary
) were performed to explore potential interactions with key cancer-related targets. Overall, the results highlight the chalcone scaffold as the main contributor to biological activity in this series and demonstrate that hybridization with gypsogenin did not enhance the cytotoxic potency.