Synthesis of egonol derivatives and their antimicrobial activities

Articles > Article · 2010

Authors: Safiye EMİRDAĞ, Tamer KARAYILDIRIM, Huseyin ANIL

Bioorganic & Medicinal Chemistry, Journal Indexed in SCI Expanded, International, WoS, 2010, vol 19, pp 1179-1188

DOI: 10.1016/j.bmc.2010.12.044

Summary

Eighteen derivatives of egonol (A-R) were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus ATCC 29213, Bacillus subtilis ATCC 6633, Candida albicans ATCC 10231 and Escherichia coli ATCC 8739 microorganisms comparing with egonol. The obtained data reported that compound B exhibited improved activities against all tested bacteria than egonol, others have shown different range of activities. (C) 2010 Elsevier Ltd. All rights reserved.

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