Hüseyin CAN
Fen Fakültesi, Biyoloji Bölümü, Moleküler Biyoloji Anabilim Dalı
Araştırma alanları: Parazitoloji, Sağlık Bilimleri, Tıp, Temel Bilimler, Temel Tıp Bilimleri, Yaşam Bilimleri, Mikrobiyoloji, Biyoteknoloji, İmmünoloji, Moleküler Biyoloji ve Genetik
Yayınlar
- In vitro expression and seroreactivity of Toxoplasma gondii GRA1 protein encoded by unmodified and nucleoside-modified mRNA constructs (2026)
- Molecular prevalence of Wolbachia endosymbiont in fleas (Ctenocephalides felis) collected from goats in Türkiye (2026)
- Comparison of the efficacy of cell wall disruption methods for Saccharomyces cerevisiae INVSc1 cells expressing Toxoplasma gondii recombinant ROP6 protein (2026)
- An ELISA Using a T. gondii GRA6-Derived Peptide as Antigen Successfully Detected Ovine Toxoplasmosis (2026)
- Screening for SARS-CoV-2 in different sheep and goat breeds in Turkiye using in-house ELISAs and real-time PCR (2026)
- A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against SARS-CoV-2 delta challenge in K18-hACE2 transgenic mice (2026)
- <i>In silico</i> identification of <i>Leishmania</i> GP63 protein epitopes to generate a new vaccine antigen against leishmaniasis (2025)
- DNA Vaccines, an Innovative Vaccine Platform against COVID-19 (2025)
- Recombinant ROP6 protein expressed in Saccharomyces cerevisiae INVSc1 cells induced strong immune response and provided significant protection against toxoplasmosis (2025)
- Genetic characterization of the Prion Protein Gene in the indigenous Nguni cattle breed of the Kingdom of Eswatini (2025)
- An optimized ROP6 mRNA construct successfully expressed immunogenic Toxoplasma gondii ROP6 protein in cell culture (2025)
- Molecular prevalence and genetic characterization of Enterocytozoon bieneusi in cattle in a dairy farm in Türkiye (2025)
- Molecular Investigation of Anaplasma spp. and Genotype Profile of A. ovis in Sheep from Different Farms in Türkiye (2025)
- Exploring the Therapeutic Potential of Bee Venom: Computational Analysis of Molecular Interactions with Cellular Targets (2025)
- Mitotyping of random bred cats and pure breed cats (Turkish Angora and Turkish Van) using non-repetitive mitochondrial DNA control region (2024)
- Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against Anaplasma ovis using immunoinformatic tools (2024)
- Development of a "Rapid-Crypto Colorimetric LAMP Test" to Detect Cryptosporidiosis in Feces of Newborns Calves (2024)
- Genetic characterization of Toxoplasma gondii strains isolated from humans living in ˙ Izmir, Türkiye (2024)
- First report of a novel 108 bp deletion and five novel SNPs in PRNP gene of stray cats and in silico analysis of their possible relation with feline spongiform encephalopathy (2024)
- Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production (2024)
- A novel DNA vaccine encoding the SRS13 protein administered by electroporation confers protection against chronic toxoplasmosis (2024)
- Molecular prevalence and genotypes of Enterocytozoon bieneusi in cancer patients under chemotherapy in Aegean region of Türkiye (2024)
- Dışkı Örneklerinin İncelenmesi (2024)
- Toksoplazmozise Karşı Multivalan mRNA Aşısı Geliştirilmesi (2024)
- DENDRİTİK HÜCRE BAZLI AŞILAR: MEKANİZMALAR, ALT TİPLER VE KLİNİK UYGULAMALAR (2024)
- IMMUNOGENICITY ANALYSIS OF EPITOPES DERIVED FROM BARTONELLA HENSELAE LEMA, MOPA AND VCEA PROTEINS (2024)
- TOXOPLASMA GONDII MIC17A PROTEİNİN AŞI VE SEROLOJİK TANIDA ÖNEMİ OLAN EPİTOP BÖLGELERİNİN IN SILICO KEŞFİ (2024)
- Development of a Novel GRA8 DNA Vaccine to Prevent Toxoplasma gondii Infection in Sheep- (2024)
- Memeli Süspanse HEK293F Hücrelerde Aşı Adayı Toxoplasma gondii GRA1 ve ROP6 Rekombinant Proteinlerinin Ekspresyonu, Saflaştırılması ve İmmünojenisitesi (2024)
- PNEUMOCYSTİS JİROVECİİ TANISI İÇİN HIZLI KOLORİMETRİK LAMP TESTİNİN GELİŞTİRİLMESİ VE ANALİTİK DUYARLILIĞIN BELİRLENMESİ (2024)
- Vaccine antigen discovery: a breakthrough in genomic era (2024)
- Newly developed peptide-ELISA successfully detected anti-IgG antibodies against Maedi-Visna virus in sheep (2024)
- Computational identification of monkeypox virus epitopes to generate a novel vaccine antigen against Mpox (2024)
- Vaccine antigen discovery: a breakthrough in genomic era (2024)
- Author Correction: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts (2024)
- Computational Analysis Shows Strong Interactions between Snake Venom Molecules and Cell Receptors (2024)
- Genotyping of Enterocytozoon bieneusi isolates detected in stray cats of İzmir, Türkiye (2023)
- A preliminary study to develop a lateral flow assay using recombinant GRA1 protein for the diagnosis of toxoplasmosis in stray cats (2023)
- An In house ELISA using recombinant GRA1 and BAG1 proteins as antigen successfully detected Toxoplasma gondii infection in a flock of sheep suffering from abortions (2023)
- Molecular and bioinformatics evaluation of PRNP as a candidate gene for successful suicidal behavior (2023)
- Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
- The Importance of Vaccines in a Sustainable Healthy Society (2023)
- Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
- The Importance of Vaccines in a Sustainable Healthy Society (2023)
- An Investigation into The Frequency and Causes of Fleas in Goat Farms (2023)
- Leishmania infantum DNA Aşısı Adayı Gp63 Proteinin in silico Analizi (2023)
- Toxoplasma gondii’nin Her Üç Dönemine Karşı Etkili MIC3 Proteininin Saccharomyces cerevisiae Tabanlı Rekombinant Protein Aşı Stratejisinde Kullanılması Amacıyla in silico Analizlerinin Gerçekleştirilmesi (2023)
- Immunogenicity and Protective Efficacy of A Novel DNA Vaccine Expressing Toxoplasma gondii SRS13 Protein Against Chronic Toxoplasmosis (2023)
- Toksoplazmozise Karşı DNA Aşısının Geliştirilmesi (2023)
- Molecular prevalence of Enterocytozoon bieneusi in stray cats of İzmir, Türkiye (2023)
- Molecular prevalence and genetic diversity of Hepatozoon spp. in stray cats of İzmir, Türkiye (2023)
- Development and Sensitivity Determination of 18S rRNA Gene-specific Fast Loop-mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Acanthamoeba (2023)
- Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
- Applicability evaluation of mtDNA based molecular identification in mosquito species/subspecies/biotypes collected from Thessaloniki, Greece (2023)
- In silico discovery of epitopes of gag and env proteins for the development of a multi-epitope vaccine candidate against Maedi Visna Virus using reverse vaccinology approach (2023)
- A preliminary study to develop a lateral flow assay using recombinant GRA1 protein for the diagnosis of toxoplasmosis in stray cats (2023)
- Genetic characterization of Bartonella henselae samples isolated from stray cats by multi-locus sequence typing (2023)
- Aşı Antijen Keşfi (2023)
- Aşı Geliştirmede Biyoinformatik ve İmmünoinformatik (2023)
- mRNA Aşıları (2023)
- Toxoplasma gondii ROP6 mRNA Aşı Transkriptlerinin Üretimi ve Rekombinant ROP6 Protein İmmünojenisitesi (2023)
- Molecular Prevalence of Enterocytozoon Bieneusi in Stray Cats of İzmir, Türkiye (2023)
- Immunogenicity of a xenogeneic multi-epitope HER2<sup>+</sup>breast cancer DNA vaccine targeting the dendritic cell restricted antigen-uptake receptor DEC205. (2022)
- Designing DNA vaccines with immuno-informatics tools (2022)
- mRNA Vaccines against Parasitic Infections (2022)
- Vaccines against Parasitic Infections (2022)
- Molecular prevalence of Blastocystis sp. and subtype diversity in fecal samples collected from cattle in dairy farms in Turkey (2022)
- Molecular investigation of Blastocystis sp. and its subtypes in cancer patients under chemotherapy in Aegean region, Turkey (2022)
- Molecular prevalence and genetic diversity of Bartonella spp. in stray cats of İzmir, Turkey (2022)
- Development of multistage recombinant protein vaccine formulations against toxoplasmosis using a new chitosan and porin based adjuvant system (2022)
- Investigation of Genetic Diversity of Toxoplasma gondii Strains Isolated from Poultry and Toxoplasmosis Seroprevalance (2022)
- Investigation of Echinococcus granulosus and Echinococcus multilocularis frequency in patients administered to Ege University Faculty of Medicine Molecular Parasitology Laboratory between 2007-2019 using multiplex real-time PCR targeting 12s rRNA gene (2022)
- Toxoplasma gondii’ye Karşı Geliştirilen DNA Aşılarına Genel Bir Bakış (2022)
- Toksoplazmozise Karşı Geliştirilen Biyoteknolojik Tabanlı Rekombinant Protein Aşıları (2022)
- Ege Üniversitesi Tıp Fakültesi Hastanesinde Toksoplazmozis Sıklığının Real-Time PZR ile Belirlenmesi (2022)
- Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against Anaplasma ovis using immunoinformatic tools (2022)
- Investigation of the Genetic Diversity and Flea-Borne Pathogens in Ctenocephalides Felis Samples Collected from Goats in İzmir and Şanlıurfa Provinces of Turkey (2022)
- Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in ?Izmir and S , anl?urfa provinces of Turkey (2022)
- Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in ?Izmir and S , anl?urfa provinces of Turkey (2022)
- mRNA aşılarının etkinliğinin arttırılması: sentetik mRNA tasarımı (2022)
- T. gondii GRA8 DNA Vaccines (2022)
- In silico vaccine design against influenza A and B viruses (2022)
- A novel stabile trimeric vaccine antigen against the wild type SARS COV-2 and Delta variant (2022)
- A novel approach for in silico design of DNA vaccine candidate against latent Toxoplasmosis (2022)
- Bioinformatics analysis and protein production of recombinant protein vaccine against Toxoplasma gondii. (2022)
- Low frequency of protective variants at regulatory region of PRNP gene indicating the genetically high risk of BSE in Ethiopian Bos indicus and Bos taurus africanus (2022)
- Rapid detection of Toxoplasma gondii DNA in cat feces using colorimetric loop-mediated isothermal amplification (LAMP) assays targeting RE and B1 genes (2022)
- Molecular prevalence and subtyping of Cryptosporidium spp. in fecal samples collected from stray cats in İzmir, Turkey. (2022)
- Development of a new serotyping ELISA for Toxoplasma gondii type II, type III and Africa 1 lineages using in silico peptide discovery methods, well categorized feline and human outbreak serum samples (2022)
- Toxoplasma gondii RE ve B1 Genlerini Hedefleyen Kolorimetrik LAMP Testlerinin Geliştirilmesi ve PCR ile Doğrulanmış Kedi Dışkı DNA Örneklerinde Performanslarının Karşılaştırılması (2021)
- İzmir İli Sokak Kedilerinden Toplanan Dışkı Örneklerinde Cryptosporidium spp.'nin Polimeraz Zincir Reaksiyonu Yöntemi ile Araştırılması ve Alt Tiplendirilmesi (2021)
- Cryptosporidiosis outbreak on a dairy farm: Detection of Cryptosporidium parvum as a causative agent in the water source (2021)
- Immunogenicity of a DNA Vaccine Encoding Chimeric Multi-Epitope HER2 antigen against HER2+ Breast Cancer by Targeting the Chimeric Antigen to Dendritic Cells (2021)
- Toxoplasma gondii 529 baz çifti büyüklüğünde tekrar bölgesine (RE) özgü hızlı döngü aracılı izotermal amplifikasyon testinin geliştirilmesi ve analitik hassasiyetinin belirlenmesi (2021)
- Molecular prevalence and subtyping of Blastocystis sp. isolates in stray cats of İzmir, Turkey: First report of “ST4 allele 42” in cats (2021)
- Administration of Four Different COVID-19 pcDNA 3.1 DNA Vaccine Prototypes Using Intradermal Electroporation and Assessment of Their Immunogenicity in BALB/c mouse (2021)
- Keçilerden Toplanan Kedi Pirelerinin (Ctenocephalides felis) Genetik Çeşitliliğinin COX1 Gen Analizi ile Araştırılması (2021)
- mRNA aşıları (2021)
- Breast Cancer Vaccines current status and future approach (2021)
- Administration of Four Different COVID-19 pcDNA 3.1 DNA Vaccine Prototypes Using Intradermal Electroporation and Assessment of Their Immunogenicity in BALB/c mouse (2021)