Diverse effects of taurine on vascular response and inflammation in GSH depletion model in rabbits
Articles > Article · 2016
Authors: Gönen ÖZŞARLAK SÖZER, Gülnur SEVİN, H. H. OZGUR, Günay YETİK ANACAK, Zeliha KERRY
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, Journal Indexed in SCI Expanded, International, 2016, vol 20, pp 1360-1372
Summary
OBJECTIVE: A reduction in GSH and an increase in free radicals are observed in inflammatory diseases, indicating oxidative stress. Taurine protects cells from the cytotoxic effects of inflammation. There have been limited studies to date evaluating the effect of taurine in oxidative stress-induced vascular dysfunction and its role in vascular inflammatory diseases. Therefore, we aimed to investigate the effect of taurine on the regulation of vascular tonus and vascular inflammatory markers in rabbit aortae and carotid arteries in oxidative stress-induced by GSH depletion.