Günay YETİK ANACAK

Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakoloji Anabilim Dalı

Research areas: Health Sciences, Pharmacology and Therapeutics, Natural Sciences, Medicine, Life Sciences, Professional Sciences, Pharmacology, Fundamental Medical Sciences, Basic Pharmaceutics Sciences, Molecular Biology and Genetics

Publications

• Osthole improves erectile function by increasing endogenous H2S production (2025)
• Isoimperatorin induces relaxation in mice corpus cavernosum via increasing hydrogen sulfide (H2S) synthesis (2025)
• Borax pentahydrate as a promising boron-based angiogenesis inhibitor (2025)
• In Vitro Drug Release Kinetics and Antioxidant Activity of Metformin-Loaded Niosomes (2025)
• Isoimperatorin induces relaxation in mice corpus cavernosum via increasing hydrogen sulfide (H2S) synthesis (2024)
• Evaluation of Borax Pentahydrate as a Novel Antiangiogenic Agent (2023)
• The Effects of Novel Triazolopyrimidine Derivatives on H2S Production in Lung and Vascular Tonus in Aorta (2023)
• Hydrogen Sulfide (2023)
• Relaxation mechanisms of chloroform root extracts of Prangos heyniae and Prangos uechtritzii on mouse corpus cavernosum (2022)
• PRANGOS HEYNIAE RELAXES MURINE PENILE TISSUE VIA INCREASING NO AND H2S SYNTHESIS (2022)
• THE RELAXANT MECHANISMS OF PRANGOS UECHTRITZII ROOTS IN MOUSE CORPUS CAVERNOSUM (2022)
• Cardiovascular Remodeling: Relationship Between Angiotensin and Nitric Oxide (2021)
• A new target for neuroprotective effect of serotonin:H2S (2021)
• Fare aortasinda karbon monoksit aracılı vasküler yanıtlar ve diğer gazotransmiterler ile ilişkisi (2021)
• DOES HYDROGEN SULFIDE CONTRIBUTE TO THE EFFECT OF OSTHOLE ON ERECTILE FUNCTION? (2021)
• THE ROLE OF HYDROGEN SULFIDE (H2S) IN THE VASOCONSTRICTIVE EFFECTS OF SEROTONIN (5-HT) (2021)
• Comparative evaluation of relaxant effects of three prangos species on mouse corpus cavernosum: Chemical characterization and the relaxant mechanisms of action of P. pabularia and (+)-oxypeucedanin (2021)
• Evaluation of Smoking and Other Tobacco Product Habits of Ege University Faculty of Health Sciences Students: A cross-sectional Survey Study (2020)
• Evaluation of Smoking and Other Tobacco Product Habits of Ege University Faculty of Health Sciences Students: A cross-sectional Survey Study (2020)
• The journey from ethnobotanical studies to pharmacological target: The effect of imperatorin and isoimperatorin on penile relaxation. (2020)
• Hydrogen sulfide-targeted molecules may be new therapeutic targets for pulmonary arterial hypertension. (2020)
• Drug Repurposing in the Treatment of COVID-19 (2020)
• The effect of New Synthesized Resveratrol Derivate H1 on angiogenesis (2020)
• Effect of CORM-2 Molecule on Vascular Tonus in Penile Tissue (2020)
• The role of resistin on metabolic syndrome‐induced erectile dysfunction and the possible therapeutic effect of Boldine (2020)
• Drug Repurposing in the Treatment of COVID-19 (2020)
• Fare Penil Dokusunda Gevşetici Etki Gösteren Endemik Bir Bitki: Prangos uechtritzii BOISSHAUSSKN (2019)
• Fare Penil Dokusunda Gevşetici Etki Gösteren Endemik Bir Bitki: Prangos uechtritzii BOISSHAUSSKN (2019)
• 1,4-dihydropyridine-benzylidenhydrazon derived AChE inhibitor induces H2S formation. (2019)
• Tracking the Oxypeucedanin: from ethnobotanical studies to pharmacological target (2019)
• Nonsteroidal anti-inflammatory drugs– What do we (not) know about them (2019)
• 1,4-dihydropyridine-benzylidenhydrazon derived AChE inhibitor induces H2S formation (2019)
• Tracking oxypeucedanin: from ethnobotanical studies to pharmacological target (2019)
• Design and synthesis of 1,4-dihydropyridine derivatives aspotential cholinesterase inhibitorswith H2S releasing group (2018)
• Effects of Prangos heyniae H.Duman&M.F.Watson Roots on Erectile Function (2018)
• Investigation of changes in vWF expression in rabbit carotid artery collar model (2018)
• The Effect of Prangos pabularia Lindl. on erectile dysfunction associated with H2S (2018)
• . Effect of the triazolopyrimidine compound on endogenous H2S levels in lung tissue homogenates: A scaffold hopping application on resveratrol derıvatıves. (2018)
• Effects of Prangos heyniae H.DumanM.F.Watson Roots on Erectile Function (2018)
• A Merging Strategy Application: Tacrine-Benzylidenehydrazone Hybrids as Potent ChE Inhibitors with Metal Binding and Neuroprotective Properties (2018)
• Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis (2018)
• A new multitargeted drug candidate in Alzheimer disease: 1,4-dihydropyridine-benzylidenhydrazon derived AChE inhibitor (2018)
• FLUVASTATİNİN TAVŞAN KAROTİD ARTERİ YAKA MODELİNDE İNTİMAL KALINLAŞMA ÜZERİNE ETKİLERİ (2018)
• A NEW MULTITARGETED DRUG CANDIDATE IN ALZHEIMER DISEASE: 1,4-DIHYDROPYRIDINE-BENZYLIDENHYDRAZON DERIVED AChE INHIBITOR (2018)
• H2S FORMATION IN LIVER IS INDUCED BY ZMP17 AND ZMP20 (2018)
• Prangos pabularia Lindl. erektil disfonksiyon için çözüm olabilir mi? (2018)
• EFFECT of THE TRIAZOLOPYRIMIDINE COMPOUND on ENDOGENOUS H2S LEVELS in LUNG TISSUE HOMOGENATES:A SCAFFOLD HOPPING APPLICATION on RESVERATROL DERIVATIVES (2018)
• Effects of prangos uechtritzii BoissHausskn roots on erectile disfunction (2018)
• EFFECTS OF PRANGOS UECHTRITZII BOISSHAUSSKN ROOTS ON ERECTILE DISFUNCTION (2018)
• Investigation of changes in vWF expression in rabbit carotid artery collar model (2018)
• The anti-angiogenic potential of (+/-) gossypol in comparison to suramin (2018)
• Hydrogen sulfide: a candidate multitarget ligand for cardiovascular diseases (2018)
• genel anestezikler ve terapotik gazlar (2017)
• gaz formundaki nörotransmitterlerde güncel durum (2017)
• Yeni sentezlenen resveratrol türevleri fare aortasında gevşemeye ve hidrojen sülfit oluşumuna neden olurlar (2017)
• Resveratrol analog induces hydrogen sulfide formation and vasorelaxation (2017)
• ALZHEİMER TEDAVİSİNDE ÇOK HEDEFLİ BİR İLAÇ ADAYI: 1,4-DİHİDROPİRİDİN-BENZİLİDENHİDRAZON TÜREVİ ASETİLKOLİN ESTERAZ İNHİBİTÖRÜ (2017)
• The role of eNOS on the compensatory regulation of vascular tonus by H2S in mouse carotid arteries (2017)
• The relaxant effect of slow releasing hydrogen sulfide donors GYY4137 and AP66 on human saphenous veins and the role of caveola (2016)
• L cysteine Hydrogen sulfide pathway is impaired under oxidative stress in mice aorta (2016)
• Resveratrol enhances endogenous H2S dependent relaxation in vascular tissues (2016)
• İlaç etkileşimleri (2016)
• Role of MMP2 on vascular reactivity changes in early atherosclerosis (2016)
• Effects of taurine in a model of oxidative stress induced by gluthation depletion in rabbit carotid arteries (2016)
• hsp90: A regulator of NO and H2S induced vascular relaxation (2016)
• Do penile hemodynamic change in the presence of hydrogen sulfide H2S donor in the metabolic syndrome induced erectile dysfunction (2016)
• Diverse effects of taurine on vascular response and inflammation in GSH depletion model in rabbits. (2016)
• New drug candidates targeting hydrogen sulfide Poly Pharmacology expanding paul Ehrlich s magic bullet concept (2016)
• oxidative stress decreases hydrogen sulfide formation (2016)
• A new mechanism for beneficial effect of resveratrol Hydrogen sulfide H2S formation (2016)
• Diverse effects of taurine on vascular response and inflammation in GSH depletion model in rabbits (2016)
• The effect of boldin on metabolic syndrome induced erectile dysfunction (2016)
• Hydrogen sulfide: A novel mechanism for the vascular protection by resveratrol under oxidative stress in mouse aorta (2016)
• Role of Six Trans Membrane Protein of Prostate STAMP Proteins in Prostate Cancer Relation with Survival Genes (2016)
• The role of Six Trans membrane protein of prostate STAMP Proteins in prostate cancer Relation with survival genes (2016)
• H2S a new target for vascular function in penile tissues (2015)
• Çocuklarda akılcı ilaç kullanımı (2015)
• Resveratrol nitrik oksitten bağımsız şekilde endojen Hidrojen sülfür yapımını uyarır (2015)
• Resveratrol Stimulates Hydrogen Sulfide (H2S) Formation to Relax Murine Corpus Cavernosum (2015)
• Hydrogen sulfide is involved in the antioxidant effects of taurine (2015)
• The role of hydrogen sulfide on the regulation of vascular tonus in mice aorta and relation with taurine (2015)
• YAVAŞ SALIMLI H2S DONÖRLERİ GYY4137 VE AP66 NIN İZOLE İNSAN SAFEN VENİ ÜZERİNDEKİ ETKİSİ VE KAVEOLA İLE İLİŞKİSİ (2015)
• hydrogen sulfide nitric oxide relation in erectile function (2015)
• Non radioactive detection of eNOS activity an electrochemical biosensor (2015)
• French paradox and erectile dysfunction (2015)
• Taurinin vasküler tonus regülasyonu ve vasküler oksidatif stres üzerindeki yararlı etkileri için yeni bir mekanizma Hidrojen sülfür (2015)
• Erektil Fonksiyonda Hidrojen Su lfu ru n Rolu (2015)
• Caveolae depletion contributes to impaired relaxation induced by hydrogen sulfide in isolated human saphenous vein (2015)
• H2S compansates NO deficiency in murine corpus cavernosum (2014)
• Gas what: NO is not the only answer to sexual function (2014)
• Hiperkolesterolemiye bağlı erektil disfonksiyonda hsp90 aracılı eNOS kaynaklı gevşemeler azalmıştır (2013)
• Decreased eNOS relaxations and relation with hsp90 in hypercholesterolemic rabbit aorta (2013)
• Different Responses of RT-PCR Amplifications after Tumor Necrosis alpha (TNFa) Induction at Nuclear Factor kappa B (NFkB) Gene Silenced LNCaP Cells (2013)
• Fluvastatin hiperkolesterolemik etkiden bağımsız şekilde erektil disfonksiyon tedavisinde yararlı olabilir (2013)
• Functional significance of hsp90‐eNOS interaction in penile tissues (2013)
• Decreased eNOS relaxations and relation with hsp90 in hypercholesterolemic rabbit aorta (2013)
• Functional significance of hsp90-eNOS interaction in penile tissues (2013)
• Different Responses of RT‐PCR Amplifications after Tumor Necrosis alpha (TNFa) Induction at Nuclear Factor kappa B (NFkB) Gene Silenced LNCaP Cells (2013)
• P10 New mechanism for the beneficial effect of sildenafil on erectile function: H2S (2013)
• Aortanın endotelyal disfonksiyonunda fluvastatin tedavisi ve hsp90 ın rolü (2013)

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