Kemal Sami KORKMAZ
Mühendislik Fakültesi, Biyomühendislik Bölümü, Biyomühendislik Anabilim Dalı
Araştırma alanları: Sağlık Bilimleri, Temel Bilimler, Tıp, Yaşam Bilimleri, Moleküler Biyoloji ve Genetik, Temel Tıp Bilimleri, Dahili Tıp Bilimleri, Kanser Moleküler Biyolojisi, Sitogenetik, Tıbbi Biyoloji
Yayınlar
- Proteomic Analysis Reveals Trace O-Glycosylation Signatures of Honeybee Venom Melittin (2026)
- The G protein‐coupled receptor GPR 89 A is a novel potential therapeutic target to overcome cisplatin resistance in NSCLC Calu1 cells (2025)
- HN1 Functions in Protein Synthesis Regulation via mTOR ‐ RPS6 Axis and Maintains Nucleolar Integrity (2025)
- HN1 is a novel dedifferentiation factor involved in regulating the cell cycle and microtubules in SH-SY5Y neuroblastoma cells (2024)
- HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis (2024)
- Akciğer Kanserinde Cisplatin Direncinde Etkili Genetik Faktörlerin Tüm Genom CRISPR/CAS9-Tabanlı Genetik Tarama Yöntemi İle Belirlenmesi (2023)
- NKX3.1 Expression Contributes to Epithelial–Mesenchymal Transition of Prostate Cancer Cells (2023)
- Androgen receptor contributes to repairing DNA damage induced by inflammation and oxidative stress in prostate cancer (2023)
- NKX3.1 Expression Contributes to Epithelial-Mesenchymal Transition of Prostate Cancer Cells (2023)
- The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric Cancer (2023)
- HN1 Is Enriched in the S-Phase, Phosphorylated in Mitosis, and Contributes to Cyclin B1 Degradation in Prostate Cancer Cells (2023)
- Mitotic Kinase Inhibitors as Therapeutic Interventions for Prostate Cancer: Evidence from In Vitro Studies (2023)
- Androgen receptor contributes to repairing DNA damage induced by inflammation and oxidative stress in prostate cancer (2023)
- HN1 interacts with γ-tubulin to regulate centrosomes in advanced prostate cancer cells (2021)
- Oxidative DNA Damage-Mediated Genomic Heterogeneity Is Regulated by NKX3.1 in Prostate Cancer (2019)
- Nutlin3a Contributes to the Cytoplasmic Retention of Androgen Receptor (2018)
- Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis (2018)
- 3D Cell Culture Model for Prostate Cancer Cells to Mimic Inflammatory Microenvironment (2018)
- Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis (2018)
- Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162] (2018)
- Detection of 8-OHdG as a diagnostic biomarker (2018)
- OGG1 Does not Interact with NKX3.1 and AR to Repair 8-OHdG Base Damage in LNCaP Cells (2018)
- Inflammatory Microenvironment-Mediated E-Cadherin Decrease Induces Migration in LNCaPs (2018)
- Inflammatory Microenvironment-MediatedE-Cadherin Decrease Induces Migration in LNCaPs (2018)
- Synthesis and Topoisomerase I inhibitory properties of klavuzon derivatives (2017)
- STAMP2 Effect on Inflammatory Microenvironment in the Development of Prostate Cancer (2017)
- Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention (2017)
- European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) (2017)
- Androgen Responce is Required for DNA Damage responce in oxidative stress conditions (2016)
- Androgen Responce is Required for DNA Damage Responce in Oxidative Stress Conditions (2016)
- Automated Cell Based Quantitation of 8 OHdG Damage (2016)
- Anti inflammatory effect of semi synthetıic astragalus saponıns on prostate cancer (2015)
- Semi synthetic Astragalus saponins inhibit inflammation induced carcinogenic mechanisms in LNCaP prostate cancer cells (2015)
- Quantitating 8 OHdG damage in prostate cancer as a marker of genomic heterogeneity (2015)
- Androgen Receptor plays role in menadione mediated 8OH dG damage leading to genomic heterogenity in prostate cancer Measurement of 8OH dG damage as a diagnostic tool (2015)
- Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression (2015)
- Kanser gelişiminde enflamatuvar mikroçevre ve yeniden genetik yapılanma Stres adaptasyonu (2015)
- LOSS OF ANDROGEN SIGNALING RESULTS IN ABROGATED DNA DAMAGE RESPONSE IN INFLAMMATORY MICROENVIRONMENT (2015)
- Semi synthetic Astragalus saponins inhibit inflammation induced B catenin pathway activation and migration in LNCaP prostate cancer cells (2015)
- The redox biology network in cancer pathophysiology and therapeutics (2015)
- Enflamatuvar Mikroçevrede Kanser Oluşumu (2014)
- HN1 Negatively Influences the β‐Catenin/E‐Cadherin Interaction, and Contributes to Migration in Prostate Cells (2014)
- DNA damage response (DDR) via NKX3.1 expression in prostate cells (2014)
- NKX3.1 binding to GPX2, QSCN6, SOD1, and SOD2 promoters contributes to antioxidant response regulation via transactivation (2014)
- TNF alpha-Mediated Loss of beta-Catenin/E-Cadherin Association and Subsequent Increase in Cell Migration Is Partially Restored by NKX3.1 Expression in Prostate Cells (2014)
- Organochlorine pesticides and antioxidant enzymes are inversely correlated with liver enzyme gene expression in Cyprinus carpio (2014)
- A new 5,6-dihydro-2-pyrone derivative from Phomopsis amygdali, an endophytic fungus isolated from hazelnut (Corylus avellana) (2014)
- HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate (2014)
- Oksidatif stres regülasyonunun bozulmasında inflamasyon ile indüklenen NKX3 1 protein kaybının rolü (2013)
- Early life stress‐induced histone acetylations correlate with activation of the synaptic plasticity genes Arc and Egr1 in the mouse hippocampus (2013)
- Preparation of Cytotoxci Molecules From Cycloartanes (2013)
- Oxidative Stress Regulation is Abrogated by Loss of NKX3.1 Expression in Acute and Chronic Inflammation (2012)
- Inflammatory Microenvironment Resulted in Abrogated B Catenin Signaling and Increased Cell Migration (2012)
- Inflammation-Mediated Abrogation of Androgen Signaling: An In Vitro Model of Prostate Cell Inflammation (2012)
- Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells (2012)
- Semi-synthesis of Cytotoxic Molecules From Cycloartane Type Sapogenols (2011)
- Secondary Metabolites from Phomopsis amygdali, an Endophytic Fungus Isolated from Hazelnut (Corylus avellana) (2011)
- Acute inflamation induced molecular alterations contribute prostatic tumorigenesis (2011)
- Ubiquitously Expressed Hematological and Neurological Expressed 1 Downregulates Akt-Mediated GSK3 beta Signaling, and Its Knockdown Results in Deregulated G2/M Transition in Prostate Cells (2011)
- HoxB13 associates with cell cycle regulators arrests cells at G1 S transition and its knockdown drives prostate cancer cells (2011)
- Secondary Metabolites from Phomopsis amygdali, an Endophytic Fungus Isolated from Hazelnut (Corylus avellana) (2011)
- ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line (2011)
- Inflammation results in loss of androgen receptor consequently uncontrolled proliferation in prostate cells (2011)
- Semi-Synthesis of Cytotoxic Molecules From Cycloartane Type Sapogenols (2011)
- Loss of NKX3 1 by Inflammatory Microenvironment Resulted in Uncontrolled Proliferation in Prostate Cells (2011)
- NKX3.1 contributes to S phase entry and regulates DNA damage response (DDR) in prostate cancer cell lines (2011)
- An Inflammation Model for Studing NKX3 1 Tumor Suppressor Function in LNCaP Cells (2010)
- ROS mediated DNA damage by topoisomerase inhibitors isolated from endemic Alkanna cappadocica (2010)
- Büyük Menderes Havzası Sazan Balıklarında Organoklorlu Pestisit Kalıntısı ve Enzimatik Yanıtlar: Fenotipik Aktivite ve Gen Transkripsiyon Düzeyleri (2010)
- p53 and AR downregulation mediated by cytokines in prostatic inflammatory atrophy model (2010)
- Functional characterization of HOXB13 targrts in prostate (2010)
- Cytotoxic Naphthoquinones from Alkanna cappadocica (2010)
- Chemistry and Biological Activities of Naphthoquinones from Alkanna cappadocica Boiss.& Bal (2009)
- Biological activities of Turkish Alkanna species (2009)
- Chemistry and Biological Activities of Naphthoquinones from Alkannacappadocica Boiss Bal (2009)
- Biological activities of Turkish Alkanna species (2009)
- NKX3 1 abrogates DDR and promotes growth arrest in prostate cell lines (2009)
- Chemistry and Biological Activities of Naphthoquinones from Alkanna cappadocica Boiss.& Bal (2009)
- Recombinant protein production of prostate tissue spesific NKX3 1 and STAMP1 proteins (2009)
- Biological activities of Turkish Alkanna species (2009)
- Identification of transcriptional targets of NKX3 1 (2009)
- HN1 An EGF responsive gene regulates cell cycle in prostate cancer (2009)
- Comparative Evaluation of Bio-Hydrogen Production From Cheese Whey Wastewater Under Thermophilic and Mesophilic Anaerobic Conditions (2009)
- Continuous fermentative hydrogen production from cheese whey wastewater under thermophilic anaerobic conditions (2009)
- Determination of polyphenolic constituents and biological activities of bark extracts from different Pinus species (2009)
- NKX3.1 contributes to S phase entry and regulates DNA damage response (DDR) in prostate cancer cell lines Erbaykent-Tepedelen B,Ozmen B,Varisli L,Gonen-Korkmaz C,Debelec-Butuner B,Syed HM,, et al., (2009)
- Determination of Naphthazarin Derivatives in 16 Alkanna Species by RP-LC Using UV and MS for Detection (2009)
- Ectopic expression of NKX3 1 blocks DNA damage related H2AX phosphorylation and promotes growth arrest in prostate cancer cell lines (2008)
- Endemik Alkanna türlerinden izole edilen DNA Topoizomeraz I inhibitörlerinin DNA hasarı üzerine etkisi (2008)
- Cytotoxic snd DNA Damage Effect of Topoisomerase Inhibitors Isolated From Endemic Alkanna Species on Cancer Cells (2008)
- PC 3 prostat kanseri hücre hattında HN1 geninin karakterizasyonu (2008)
- Determination of naptharazin derivatives in Turkish Alkanna species by reverse phase HPLC (2008)
- STAMP gen ailesinin prostat kanser kemik metastazı hücre hattında apoptoz yolakları ile etkileşiminin araştırılması (2007)
- Post transkripsiyonel Gen Susturma PTGSs A7r5 Hücrelerinde Depo kontrollü Kalsiyum Kanalının İşlevsel Bileşiminin Belirlenmesi (2007)
- Trichostatin A causes p53 to switch oxidative‐damaged colorectal cancer cells from cell cycle arrest into apoptosis (2007)
- Determination of Naphthazarin Derivatives in Endemic Turkish Alkanna Species by Reversed Phase High Performance Liquid Chromatography (2007)
- Is NKX3 1 a balancing factor between cell survival and apoptosis (2007)
- H2O2-associated DNA-damage induces acetylation-dependent upregulation of p21WAF1 expression in colorectal cancer cells (2006)
- Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer (2005)
- Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress (2004)