Diverse effects of calcium channel blockers in the collar model
Articles > Article · 2005
Authors: Zeliha KERRY, MUKADDER YASA, Gülnur SEVİN, Buket REEL, Günay YETİK ANACAK, A OZER
ACTA CARDIOLOGICA, Journal Indexed in SCI Expanded, International, 2005, vol 60, pp 493-499
Summary
Objective - Calcium channel blockers (CCBs) are among the most frequently prescribed cardiovascular drugs. It has been shown that these drugs have antiatherosclerotic effects in both experimental and clinical settings. However, calcium channel blockers have markedly different chemical structures and different effects on the cardiovascular system.We investigated the effect of CD-832, a Ca+2 channel antagonist, on collar-induced intimal thickening, as well as accompanied reactivity changes in rabbit carotid artery.