Synthesis and Antimicrobial Activity of Some Pyridinium Salts
Articles > Article · 2009
Authors: Vildan ALPTÜZÜN, Sülünay PARLAR ÇOŞKUN, Hüseyin TAŞLI, Ercin ERCİYAS
Molecules, Journal Indexed in SCI Expanded, International, WoS, 2009, vol 14, pp 5203-5215
DOI: 10.3390/molecules14125203
Summary
Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains.