Sülünay PARLAR ÇOŞKUN

Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Anabilim Dalı

Research areas: Health Sciences, Pharmacology and Therapeutics, Natural Sciences, Life Sciences, Basic Pharmaceutics Sciences, Chemistry, Biochemistry, Pharmaceutical Chemistry, Professional Sciences, Molecular Biology and Genetics

Publications

• Synthesis and inhibitory activity of novel N-phenethylpiperidinehydrazide hydrazones against acetylcholinesterase, butyrylcholinesterase, and β-Amyloid (1–42) as potential anti-Alzheimer agents (2026)
• Synthesis, Bioactivity and Molecular Modeling Studies on Benzimidazole Derivatives and Its Isosteres as Potent AChE / BChE and GSK3β Inhibitors for Alzheimer's Disease (2026)
• 3-(1H-pyrazole-1-yl/1H-1,2,4-triazole-1-yl)-N-propananilide Derivatives: Design, Synthesis and Neuroprotectivity Potential Against 6-OHDA Induced Neurotoxicity Model (2025)
• 3-(1H-pyrazole-1-yl/1H-1,2,4-triazole-1-yl)-N-propananilide derivatives: Design, Synthesis and Neuroprotectivity Potential Against 6-OHDA Induced Neurotoxicity Model (2024)
• N‐Substituted piperidine‐3‐carbohydrazide‐hydrazones against Alzheimer's disease: Synthesis and evaluation of cholinesterase, beta‐amyloid inhibitory activity, and antioxidant capacity (2023)
• The antibacterial activity of photodynamic agents against multidrug resistant bacteria causing wound infection (2022)
• Design, synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-β aggregation inhibition studies of substituted 4,4ʹ-diimine/4,4ʹ-diazobiphenyl derivatives (2022)
• N‐Substituted piperidine‐3‐carbohydrazide‐hydrazones against Alzheimers disease: Synthesis and evaluation of cholinesterase, beta‐amyloid inhibitory activity, and antioxidant capacity (2022)
• İlaç hedefi olarak nükleik asitler (2021)
• Photoinactivation Efficiency of Cationic Porphyrin Derivatives Against Multidrug-Resistant Wound Pathogens (2021)
• A Novel Molecule: 1‐(2,6 Dichlorobenzyl)‐4‐(2‐(2‐4‐hydroxybenzylidene)hydrazinyl)pyridinium Chloride and its Interaction with DNA (2021)
• Electrochemical Characteristics of a Novel Pyridinium Salt as a Candidate Drug Molecule and Its Interaction with DNA (2020)
• 4-Phthalimido-N,N-diethyl benzensulfonamido as MTDL for the treatment of Alzheimer’s disease and type II dabetes mellitus. (2020)
• Cholinergic Agents (2019)
• A Fusing Strategy Application: Towards Potent ChE Inhibitors with MTDL Profile (2019)
• Antidepresanlar (2019)
• Solunum Yolu İlaçları (2019)
• 1,4-dihydropyridine-benzylidenhydrazon derived AChE inhibitor induces H2S formation. (2019)
• Antibacterial activity of porphyrin derivatives against multidrug-resistant bacteria. (2019)
• Studies on novel Tacrine-Donepezil hybrids with potent MTDL profile (2019)
• Synthesis and cholinesterase inhibitory activity studies of some piperidinone derivatives (2019)
• 1,4-dihydropyridine-benzylidenhydrazon derived AChE inhibitor induces H2S formation (2019)
• Antibacterial activity of porphyrin derivatives against multidrug-resistant bacteria (2019)
• Antibacterial activity of porphyrin derivatives against multidrug-resistant bacteria (2019)
• Neuroprotective Evaluation of Some Phenylacetamide Derivatives Bearing 1,2,4-triazole with Metal Binding Property (2018)
• SYNTHESIS AND CHOLINESTERASE INHIBITORY POTENTIAL OF SOME PYRIDINIUM-3-CARBOHYDRAZIDE-HYDRAZONE DERIVATIVES (2018)
• Design, synthesis and biological activity studies on novel Tacrine-donepezile hybrides as MTDL against Alzheimer's Disease (2018)
• Design, synthesis and biological activity studies on novel tacrine-donepezil hybrides as MTDL against Alzheimer’s disease (2018)
• A Merging Strategy Application: Tacrine-Benzylidenehydrazone Hybrids as Potent ChE Inhibitors with Metal Binding and Neuroprotective Properties (2018)
• Elimination of Multi-drug Resistant Acinetobacter baumannii Strain with Various Porphyrin Derivatives Stimulated by Red Light (2018)
• Multifunctional cholinesterase inhibitors for Alzheimer's disease: Synthesis, biological evaluations, and docking studies of o/p‐propoxyphenylsubstituted‐1H‐benzimidazole derivatives (2018)
• "Synthesis and Acetylcholinesterase/Butyrylcholinesterase Inhibitory Activity Studies of Some (2,6-dichlorobenzyl)piperidine-carbohydrazides (2018)
• A NEW MULTITARGETED DRUG CANDIDATE IN ALZHEIMER DISEASE: 1,4-DIHYDROPYRIDINE-BENZYLIDENHYDRAZON DERIVED AChE INHIBITOR (2018)
• Synthesis, biological evaluation, and docking studies of some 5-chloro-2(3H)-benzoxazolone Mannich bases derivatives as cholinesterase inhibitors (2018)
• Synthesis and evaluation of pyridinium‐hydrazone derivatives as potential antitumoral agents (2018)
• Photodynamic antimicrobial activity of new porphyrin derivatives against methicillin resistant Staphylococcus aureus (2018)
• Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones (2018)
• SYNTHESIS AND BIOLOGICAL EVALUATION OF ORTHO-PROPOXYPHENYL SUBSTITUTED 1H-BENZIMIDAZOLE DERIVATIVES AS BUCHE AGENTS (2017)
• Photoinactivation with Novel Porphyrin Derivatives: An in Vitro Study on Multi-drug Resistant Escherichia coli (2017)
• ACTIVITY AGAINST CARBAPENEM RESISTANT PSEUDOMONAS AERUGINOSA OF ANTIMICROBIAL PHOTODYNAMIC THERAPY (2017)
• Mannich‐Benzimidazole Derivatives as Antioxidant and Anticholinesterase Inhibitors: Synthesis, Biological Evaluations, and Molecular Docking Study (2017)
• Synthesis and Biological Evaluation of Some Piperidine Hydrazide-Hydrazone Derivatives as AChE/BuChE Inhibitors (2017)
• Photodynamic atmicrobial activity of new porphyrin derivatives against methicillin resistant Staphylococcus aureus (2017)
• SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME QUINOXALINE DERIVATIVES AS CHOLINESTERASE INHIBITORS (2017)
• ALZHEİMER TEDAVİSİNDE ÇOK HEDEFLİ BİR İLAÇ ADAYI: 1,4-DİHİDROPİRİDİN-BENZİLİDENHİDRAZON TÜREVİ ASETİLKOLİN ESTERAZ İNHİBİTÖRÜ (2017)
• SYNTHESIS AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME 4-(3/4-NITROPHTHALIMIDO) BENZENESULFONAMIDE DERIVATIVES (2017)
• PHOTODYNAMIC ANTMICROBIAL ACTIVITY OF NEW PORPHYRIN DERIVATIVES AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (2017)
• Synthesis and Biological Evaluatıon of Ortho-Propoxyphenyl Substıtuted 1H-Benzimidazole Derivatives as Buche Agents (2017)
• Leader Compound Optimization Studies on 1H-Benzimidazole Derivatives for Alzheimer Disease (2017)
• Photoinactivation with Novel Porphyrin Derivatives: An in Vitro Study on Multi-drug Resistant Escherichia coli(Yeni Porfirin Türevleri İle Fotoinaktivasyon:Çoklu İlaç Dirençli Escherichia coli Üzerinde InVitro Çalışma ) (2017)
• Mannich-Benzimidazole Derivatives as Antioxidant and Anticholinesterase Inhibitors: Synthesis, Biological Evaluations, and Molecular Docking Study (2017)
• 1H benzimidazole derivatives as butyrylcholinesterase inhibitors synthesis and molecular modeling studies (2016)
• Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors (2016)
• Synthesis, Biological Evaluation and Molecular Docking Study of Hydrazone-Containing Pyridinium Salts as Cholinesterase Inhibitors (2016)
• 1H-benzimidazole derivatives as butyrylcholinesterase inhibitors: synthesis and molecular modeling studies (2016)
• SYNTHESIS AND ACETYLCHOLINESTERASE INHIBITOR ACTIVITY STUDIES ON N BENZYL PIPERIDINE AND N BENZYL MORPHOLINE DERIVATIVES (2015)
• SYNTHESIS AND BIOLOGICAL ACTIVITY STUDIES ON ACETOPHENONE HYDRAZONE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS (2015)
• SYNTHESIS AND BIOLOGICAL EVALUATION OF MANNICH BASES OF BENZIMIDAZOLE 2 PHENOL DERIVATIVES ASANTICHOLINESTERASE AGENTS (2015)
• Synthesis and cholinesterase inhibitory activity of some phenylacetamide derivatives bearing 1H-pyrazole and 1H-1,2,4-triazole (2015)
• Synthesis and acetylcholinesterase (AChE) inhibitory activity of some N-substituted-5-chloro-2(3H)- benzoxazolone derivatives (2014)
• Design Synthesis Biological Evaluation and MolecularModeling of 1H Benzimidazole Derivatives asAcetyl Butyrylcholinesterase Inhibitors (2014)
• Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors (2013)
• 1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood–brain barrier (2013)
• Synthesis and acetylcholinesterase(AChE) inhibitory activity of some N-substituted-5-chloro-2(3H)-benzoxazolone derivatives (2013)
• Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors (2013)
• Synthesis and acetylcholinesterase AChE inhibitory activity of some N substituted 5 chloro 2 3H benzoxazolone derivatives (2013)
• ACETHYLCHOLINESTERASE INHIBITOR ACTIVITY OF SOME QUATERNARY PYRIDINIUM HYDRAZONE DERIVATIVES (2010)
• Synthesis and Antimicrobial Activity of Some Pyridinium Salts (2009)

CV