Genistein-induced mir-23b expression inhibits the growth of breast cancer cells

Articles > Article · 2015

Authors: Çığır BİRAY AVCI, Sunde YILMAZ SÜSLÜER, Hasan Onur CAGLAR, Tugce BALCI, Duygu Döndü AYGÜNEŞ JAFARI, Yavuz Dodurga, Cumhur GÜNDÜZ

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, Journal Indexed in SCI Expanded, International, 2015, vol 1, pp 32-35

DOI: 10.5114/wo.2014.44121

Summary

Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer. This study aims to induce cellular stress by exposing genistein to determine alterations of miRNA expression profiles in MCF-7 cells.

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