Cumhur GÜNDÜZ

Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Anabilim Dalı

Research areas: Health Sciences, Medicine, Fundamental Medical Sciences, Medical Biology, Internal Medicine Sciences, Natural Sciences, Life Sciences, Molecular Biology and Genetics, Internal Diseases, Medical Genetics

Publications

The impact of inhibiting the Hippo signaling pathway effectomolecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
Correction: The impact of inhibiting the Hippo signaling pathway effector molecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
Birinapant enhances cisplatin sensitivity in epithelial ovarian cancer through modulation of apoptotic and survival signaling pathways (2026)
Analysis of fetal DNA in biological samples derived from maternal exhaled breath (2026)
Comparative evaluation of the biocompatibility and antibacterial efficacy of various toothpaste formulations (2026)
In vitro assessment of siRNA-mediated LRP5 silencing and temozolomide treatment in glioblastoma and brain cancer stem cells (2026)
Optical genome mapping identifies previously undetected causal variants in early-onset developmental epileptic encephalopathies (2026)
Investigation of viscerotropism-associated genes in Leishmania tropica strains causing visceral leishmaniasis (2026)
Gene Expression Profiling of EGFR , FGFR2 , PIK3CA , PTEN , SMAD4 , STK11 , and TP53 in Cell‐Free RNA From Exhaled Breath Condensate: Diagnostic, Prognostic, and Therapeutic Implications in Advanced Lung Adenocarcinoma (2026)
Resveratrol Modulates lncRNA Expression Profiles in Leukemia Stem Cell Line (2026)
Ksenograft Over Kanseri Modelinde Amcasertib’in Terapötik Potansiyeli (2026)
In vitro analysis of various mouthwashes: cytotoxic, apoptotic, genotoxic and antibacterial effects (2025)
Effects of 5-azacytidine and N6-methyladenosine combination on apoptosis and stemness in human breast cancer stem cells (2025)
Comparative assessment of biocompatibility of various fluoride agents in cell culture (2025)
Defeating miR-181a-3p may potentiate the effect of paclitaxel on G2/M arrest in breast cancer stem cells (2025)
Targeting leukemic stem cells: enhanced eradication via tivantinib (ARQ197) and asciminib (ABL001) with molecular docking-guided screening of therapeutic derivatives (2025)
Anti-miRNA- 155 - 5p enhances the cytotoxic efficacy of temozolomide in brain cancer stem cells (2025)
Kuzey Kıbrıs’tan İzole Edilen Kutanöz Layşmanyazis ve Kanin Layşmanyazis Suşlarının Moleküler Karakterizasyonu ve Fare Modellerinde Klinik Yansımaları (2025)
Influence of Fusobacterium nucleatum on Tumor Necrosis Factor Alpha Therapy in Ulcerative Colitis (2025)
Photobiomodulation therapy enhances surfactant production in premature rat lungs: a non-invasive therapeutic strategy for neonatal respiratory distress syndromes (2025)
Photobiomodulation therapy enhances surfactant production in premature rat lungs: a non-invasive therapeutic strategy for neonatal respiratory distress syndromes (2025)
An Overview of the Pathogenesis the Leishmaniasis: Investigation of Possible Viscerotropism Associated Genes of Viscerotropic Leishmania tropica Strains (2025)
Assessment of Exhaled Breath Condensate for ALK, RET, ROS1, and NTRK1 Fusion Transcript Detection in NSCLC: Comparison With Tissue and Liquid Biopsy Samples (2025)
Effect of photobiomodulation therapy on surfactant production increase in human lung epithelial alveolar cells (2025)
Effects of 5-azacytidine and N6-methyladenosine combination on apoptosis and stemness in human breast cancer stem cells (2025)
Investigation of anti-cancer efficiency of DZNep and Stauprimide combination in breast cancer (2025)
Exploring the Role of Long Non-Coding RNAs in Predicting Outcomes for Hepatitis B Patients (2024)
PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2024)
Preparation of dual drug-loaded polymer nanoconjugate to enhance treatment efficacy for ovarian cancer cells (2024)
Amcasertib Increases Apoptosis While Decreasing Invasive and Migrating Abilities in Breast Cancer Stem Cells (2024)
İNSAN TROFOBLAST HÜCRELERİNDE YÜKSEK GLUKOZUN PROGRAMLI HÜCRE ÖLÜM MEKANİZMALARINA ETKİSİNİN ARAŞTIRILMASI (2024)
Determination of Surfactant Production Increase in Lung Alveolar Cell Lines Using Infrared Phototherapy Method (2024)
İNSAN TROFOBLAST HÜCRELERİNDE YÜKSEK GLUKOZUN PROGRAMLI HÜCRE ÖLÜM MEKANİZMALARINA ETKİSİNİN ARAŞTIRILMASI (2024)
Investigation of the Biocompatibility and Antibacterial Activity of Different Mouthwashes (2024)
Anaplastik Tiroit Kanserinde Somatik Mutasyonların Hastaların Sağkalımına Etkisi (2024)
Preparation of dual drug-loaded polymer nanoconjugate to enhance treatment efficacy for ovarian cancer cells (2024)
Cytotoxic effects of silver nanoparticles synthesized using Asphodelus aestivus Brot. aqueous extract (2023)
Visceral Leishmaniasis Caused by Leishmania Tropica (2023)
A new scoring system to predict mortality in community-acquired pneumonia: CURB (S)-65 (2023)
Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri (2023)
İleri Evre Küçük Hücreli Dışı Akciğer Kanseri Tanılı Olguların Ekshale Soluk Havası Kondensat Örneklerinde Spesifik lncRNA’ların Biyobelirteçlere Dönüştürülmesi. (2023)
Evaluation of the effect of intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc radiotherapy (VMAT) techniques on survival response in cell lines with a new radiobiological modeling (2023)
Cancer stemness kinase inhibitor amcasertib: a promising therapeutic agent in ovarian cancer stem and cancer cell models with different genetic profiles (2023)
Distribution and Phylogenetic Analysis of Subtypes and Alleles of Blastocystis sp. in the Stool Samples Collected from Patients with Gastrointestinal Complaints in İzmir, Turkey (2023)
The effect of the ATM inhibitor AZD0156 on the radiosensitivity of human breast cancer and lung fibroblast cells (2023)
Conversion of specific lncRNAs to biomarkers in exhaled breath condensate samples of patients with advanced stage non-small-cell lung cancer (2023)
The lncRNA expression profile signature of leukemia stem cells is altered upon PI3K/mTOR inhibition: an in vitro and in silico study (2023)
The effects of PKI-402 on breast tumor models' radiosensitivity via dual inhibition of PI3K/mTOR (2023)
In vivo and In vitro Assessment of Mitochondrial Alterations in Paracetamol-Induced Kidney Injury (2023)
P18-03: In vivo and In vitro Assessment of Mitochondrial Alterations in Paracetamol-Induced Kidney Injury (2023)
STAT5 inhibitor Pimozide as a probable therapeutic option in overcoming Ponatinib resistance in K562 leukemic cells (2023)
Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death? (2022)
The Evaluation of the Relationship of Klotho and Telomerase in Obese Patients. (2022)
Investigation of the Anti-Leishmanial Effects of Prangos ferulacea and Ferula orientalis Extracts Collected from Şırnak Province Against Leishmania tropica Isolated in Turkey (2022)
Akciğer Adenokarsinomlu Olgularda Moleküler Patogenez ve Prognozun Belirlenmesinde Volatil Biyopsi. (2022)
Does MicroRNA Profile Differ in Early Onset Coronary Artery Disease? (2022)
Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells (2022)
Ponatinib ve Türkiye’de yetişen bazı endemik bitki ekstrelerinin kombinasyonlarının meme kanseri hücreleri üzerindeki etkileri (2022)
Clinical and molecular evaluation of MEFV gene variants in the Turkish population: a study by the National Genetics Consortium (2022)
Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death? (2022)
The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
Combinational effects of ponatinib and some Turkish endemic plant extracts on breast cancer cells (2022)
Enhanced Anti-cancer Potency Using a Combination of Oleanolic Acid and Maslinic Acid to Control Treatment Resistance in Breast Cancer (2022)
GLOMERÜLONEFRİT ŞÜPHESİ OLAN HASTALARDA NFAT GEN AİLESİ ÜYELERİNİN FARKLI İFADE PROFİLLERİNİN İNCELENMESİ (2022)
Exhaled breath analysis as a disease diagnosis tool (2022)
The Risk Factors and Clinical Features of Acanthamoeba Keratitis: First Time Detection of Acanthamoeba T5 Genotype from Keratitis Patients in Turkey (2022)
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS (2022)
Immunological changes during desensitization with cow’s milk: how differ from natural tolerance or nonallergic state? (2022)
The Effect of Radiofrequency Waves on Pregnant Mice in Association with Genes Involved in Neuronal Migration (2022)
Assessment of Radiation-Induced Bystander Effect in Astrocyte-Glioblastoma Cell Lines (2022)
Autochthonous transmission of Leishmania donovani and Leishmania major with all the components of infection cycle at Europe's doorstep (2022)
Origanum Sipyleum Methanol Extract in Combination with Ponatinib Shows Synergistic anti-Leukemic Activities on Chronic Myeloid Leukemia Cells (2022)
Targeting UPR signaling pathway by dasatinib as a promising therapeutic approach in chronic myeloid leukemia (2022)
Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells (2022)
Investigation of miRNA and cytokine expressions in latent tuberculosis infection and active tuberculosis (2022)
Functional roles of miR-625-5p and miR-874-3p in the progression of castration resistant prostate cancer (2022)
The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
Does MicroRNA Profile Differ in Early Onset Coronary Artery Disease? (2022)
Kistik Ekinokokkozis Hastalarında Immun Yanıt ve Echinococcus Granulosus Genotipi İle İlişkisinin İncelenmesi (2022)
Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells (2022)
Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells. (2022)
Comparative expression analysis of dasatinib and ponatinib-regulated lncRNAs in chronic myeloid leukemia and their network analysis (2022)
Comparison of the multi-epitope recombinant antigen DIPOL and hydatid fluid for the diagnosis of patients with cystic echinococcosis (2022)
SERPING1 Gene Promoter Variation in Turkish Patient with HAE (2021)
Ponatinib miRNA ifadelerini düzenleyerek meme kanseri hücrelerini hedefler (2021)
PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia (2021)
The Evaluation of Effect of Aurora Kinase Inhibitor CCT137690 in Melanoma and Melanoma Cancer Stem Cell (2021)
Enhanced Anti-Cancer Potency Using A Combination of Oleanolic Acid and Maslinic Acid to Control Treatment Resistance in Breast Cancer. (2021)
The Evaluation of Effect of Aurora Kinase Inhibitor CCT137690 in Melanoma and Melanoma Cancer Stem Cell (2021)
Dabrafenib ve Epigalokatesin-3-galat Uygulanmis Anaplatik Tiroid Kanser Modelinde Epigenetik Duzenleyici Genlerin Profilenmesi. (2021)
ASTROSİT-GBM HÜCRE HATLARINDA RADYASYONA BAĞLI BYSTANDER ETKİSİNİN KO-KÜLTÜR İLE DEĞERLENDİRİLMESİ (2021)
VS-5584’ün akciğer adenokarsinom hücresinde WNT sinyal yolağına etkisinin incelenmesi (2021)
Beyin Kanseri Kök Hücrelerinde ve Sağlıklı Beyin Kök Hücrelerinde Yes-assotiated Protein 1 (YAP1) In Vitro İnhibisyonu: Ferroptozu indükler ve Adhezyon, EMT ve Migrasyon özelliklerini baskılayarak glioblastoma ilerlemesini önler (2021)
PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia (2021)
Tumor treating fields (TTF)” ve radyoterapi kombinasyonunun beyin tümörü ve normal doku hücre hatlarında etkinliği (2021)
SERPING1 Gene Variations in Patients with Hereditary Angioedema (2021)
P-213 OBEZ HASTALARDA KLOTHO VE TELOMERAZ ILIŞKISININ DEĞERLENDIRILMESI (2021)
The effect of caffeic acid phenethyl ester on cell cycle control gene expressions in breast cancer cells (2021)
The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy (2021)
SERPING1 Gene Promoter Variation in Turkish Patient with HAE (2021)