Çığır BİRAY AVCI

Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Anabilim Dalı

Research areas: Health Sciences, Medicine, Natural Sciences, Fundamental Medical Sciences, Life Sciences, Medical Biology, Molecular Biology and Genetics, Moleculer Biology of Cancer, Internal Medicine Sciences, Internal Diseases

Publications

• Correction: The impact of inhibiting the Hippo signaling pathway effector molecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
• KEKİK YAĞININ MİDE KANSERİ PATOGENEZİNDE EPİGENETİK MEKANİZMALAR ÜZERİNDEKİ ROLÜ (2026)
• The impact of inhibiting the Hippo signaling pathway effectomolecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
• The impact of the telomerase inhibitor on the Wnt signaling pathway in breast cancer and breast cancer stem cells (2026)
• TRANSCRIPTIONAL MODULATION OF THE WNT/β-CATENIN SIGNALING PATHWAY BY ORIGANUM ONITES L. ESSENTIAL OIL: A LINK TO EPIGENETIC REGULATION IN GASTRIC CANCER (2026)
• Mitochondrial Dynamics-Related Gene Regulation by Epigenetic Suppression of GCN5 Exerts Neuroprotective Effects in Rotenone-Induced Parkinson’s Disease Model (2026)
• Mitochondrial Dynamics-Related Gene Regulation by Epigenetic Suppression of GCN5 Exerts Neuroprotective Effects in Rotenone-Induced Parkinson’s Disease Model (2026)
• BET inhibition enhances temozolomide sensitivity in cervical cancer cells through ALDH suppression and epigenetic reprogramming (2026)
• Temozolomide and ruxolitinib combination modulates miRNA-associated regulatory networks in glioblastoma stem cells (2026)
• Microfluidic Biofabrication of a Hydrogel Vessel‐Like Structure for Interrogating Tumor Cell Propagation in a Breast Cancer‐on‐a‐Chip Model (2026)
• miR ‐640 Enhances Abemaciclib Sensitivity by Suppressing CDK Inhibitor Resistance‐Associated Genes in Breast Cancer Cells (2026)
• The anticancer potential of Origanum onites L. in gastric cancer through epigenetic alterations (2025)
• Defeating miR-181a-3p may potentiate the effect of paclitaxel on G2/M arrest in breast cancer stem cells (2025)
• Anti-miRNA- 155 - 5p enhances the cytotoxic efficacy of temozolomide in brain cancer stem cells (2025)
• PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2025)
• Precision oncology: Using cancer genomics for targeted therapy advancements (2025)
• Electrodeposition of carbon nanotubes and conjugation of arginyl-glycyl-aspartic acid for the following of glioblastoma cells on bionanocomposites (2025)
• Modulating Cancer Stem Cell Characteristics in CD133+ Melanoma Cells through Hif1α, KLF4, and SHH Silencing (2025)
• Multimodal urinary biomarker panel achieves superior prostate cancer detection accuracy and reduces unnecessary biopsies (2025)
• Molecular mechanisms of gut microbiota dysbiosis and metabolites in Alzheimer’s disease pathogenesis: implications for precision therapeutics (2025)
• Metformin exerted tumoricidal effects on colon cancer tumoroids via the regulation of autophagy pathway (2025)
• The Interplay Between Viral Infection and Cell Death: A Ping‐Pong Effect (2025)
• Dual role of electrical stimulation and a biomimetic matrix in neural differentiation within a microfluidic platform (2025)
• Toll-like receptor-4 signaling pathway influenced the exosome biogenesis and angiogenesis in human triple-negative breast cancer cells (2025)
• Megalin (LRP2) Expression Patterns in Prostate Cancer Stem Cells and Metastatic Subtypes: Implications for Tumor Progression and Metabolism (2025)
• Development of a Biomimetic Human Airway Epithelial Barrier-on-a-chip and Ex Vivo Human Airway Model: Tools for Evaluating Silica PM 2.5 Particle Exposure (2024)
• Propofol orchestrates long non-coding RNAs in MCF7 cells, unraveling new avenues for breast cancer intervention (2024)
• PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2024)
• Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications (2024)
• Machine learning in oncological pharmacogenomics: advancing personalized chemotherapy (2024)
• The future of cancer therapy: exploring the potential of patient-derived organoids in drug development (2024)
• Comprehensive analysis of resilience of human airway epithelial barrier against short‐term PM2.5 inorganic dust exposure using in vitro microfluidic chip and ex vivo human airway models (2024)
• Comprehensive analysis of resilience of human airway epithelial barrier against short-term PM2.5 inorganic dust exposure using in vitro microfluidic chip and ex vivo human airway models (2024)
• ICU patient-on-a-chip emulating orchestration of mast cells and cerebral organoids in neuroinflammation (2024)
• ICU patient-on-a-chip emulating orchestration of mast cells and cerebral organoids in neuroinflammation (2024)
• Impact of KLF4, SHH, and Hif1a Knockdown on miRNA Expression in Malign Melanoma Cancer Stem Cells (2024)
• Telomerase inhibition in breast cancer and breast cancer stem cells: a brief review (2024)
• Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells (2024)
• Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri (2023)
• Evaluation of the anticancer effect of telomerase inhibitor BIBR1532 in anaplastic thyroid cancer in terms of apoptosis, migration and cell cycle (2023)
• Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids (2023)
• Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri (2023)
• Doxorubicin-induced senescence promotes resistance to cell death by modulating genes associated with apoptotic and necrotic pathways in prostate cancer DU145 CD133+/CD44+ cells (2023)
• HDAC9/p300/F-actin immunoexpression and migration analysis for malignant melanoma stem cell (2023)
• Photodynamic therapy potential of cobalt phthalocyanine in triple-negative breast cancer (2023)
• Distribution and Phylogenetic Analysis of Subtypes and Alleles of Blastocystis sp. in the Stool Samples Collected from Patients with Gastrointestinal Complaints in İzmir, Turkey (2023)
• Differentiation of Neurons, Astrocytes, Oligodendrocytes and Microglia From Human Induced Pluripotent Stem Cells to Form Neural Tissue-On-Chip: A Neuroinflammation Model to Evaluate the Therapeutic Potential of Extracellular Vesicles Derived from Mesenchymal Stem Cells (2023)
• Phenolated alginate hydrogel induced osteogenic properties of mesenchymal stem cells via Wnt signaling pathway (2023)
• Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids (2023)
• Distribution and Phylogenetic Analysis of Subtypes and Alleles of Blastocystis sp. in the Stool Samples Collected from Patients with Gastrointestinal Complaints in Izmir, Turkey (2023)
• Evaluation of the anticancer effect of telomerase inhibitor BIBR1532 in anaplastic thyroid cancer in terms of apoptosis, migration and cell cycle (2023)
• The effects of PKI-402 on breast tumor models’ radiosensitivity via dual inhibition of PI3K/mTOR (2023)
• EPIGALLOCATECHIN GALLATE SENSITIZES PANCREATIC CANCER CELLS TO GEMCITABINE BY MODULATING MICRORNA EXPRESSION PROFILE (2023)
• Molecular Aspect of Propofol's Effect on Cytotoxic and Long Non-Coding RNA (lncRNA) Expressions in MCF-7 (2023)
• Unlocking the potential of microRNAs: machine learning identifies key biomarkers for myocardial infarction diagnosis (2023)
• A selective androgen receptor modulator, S4, displays robust anti-cancer activity on hepatocellular cancer cells by negatively regulating PI3K/AKT/mTOR signalling pathway (2023)
• In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase (2023)
• Decellularized plant-derived vasculature-on-a-chip interacting with breast cancer spheroids to evaluate a dual-drug therapy (2023)
• Adipose Tissue Mesenchymal Stem Cells Exposed To Oxytocin and Sunitinib are Synergistically Dystrophic (2022)
• INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS (2022)
• Investigating the Effects of a Synthetic Cannabinoid on the Pathogenesis of Leukemia and Leukemic Stem Cells: A New Therapeutic Approach (2022)
• Adipose Tissue Mesenchymal Stem Cells Exposed To Oxytocin and Sunitinib are Synergistically Dystrophic (2022)
• A drug-responsive multicellular human spheroid model to recapitulate drug-induced pulmonary fibrosis (2022)
• Noncoding way of the metastasis (2022)
• Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation (2022)
• Future Perspectives of Phytochemicals in Cancer Therapy (2022)
• Ponatinib ve Türkiye’de yetişen bazı endemik bitki ekstrelerinin kombinasyonlarının meme kanseri hücreleri üzerindeki etkileri (2022)
• Investigation of Cytotoxic and Apoptotic Effects of Disodium Pentaborate Decahydrate on Ovarian Cancer Cells and Assessment of Gene Profiling (2022)
• Investigation of cytotoxic and apoptotic effects of disodium pentaborate decahydrate on ovarian cancer cells and assessment of gene profiling (2022)
• Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death? (2022)
• Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes (2022)
• A drug-responsive multicellular human spheroid model to recapitulate drug-induced pulmonary fibrosis (2022)
• The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
• The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
• Combinational effects of ponatinib and some Turkish endemic plant extracts on breast cancer cells (2022)
• Enhanced Anti-cancer Potency Using a Combination of Oleanolic Acid and Maslinic Acid to Control Treatment Resistance in Breast Cancer (2022)
• OVER KANSERİNDE BOR MİNERALİNİN GÜNCEL TEDAVİ ALANLARI (2022)
• Hücre Ayırma Stratejileri (2022)
• Hücre Ölümünün Tersine Çevrilmesi: Anastaz (2022)
• Chapter 6 - Noncoding way of the metastasis (2022)
• Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation (2022)
• Future Perspectives of Phytochemicals in Cancer Therapy (2022)
• A drug-responsive multicellular human spheroid model to recapitulate drug-induced pulmonary fibrosis (2022)
• Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes (2022)
• Epigenetic signatures in gastric cancer: current knowledge and future perspectives (2022)
• Diagnostic Potential of Autophagy-5 Protein, Apolipoprotein B-48, and Oxidative Stress Markers in Serum of Patients with Early-Stage Ischemic Stroke (2022)
• Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells (2022)
• Origanum Sipyleum Methanol Extract in Combination with Ponatinib Shows Synergistic anti-Leukemic Activities on Chronic Myeloid Leukemia Cells (2022)
• Molecular perspective on targeted therapy in breast cancer: a review of current status (2022)
• Conditioned medium from amniotic fluid mesenchymal stem cells could modulate Alzheimer's disease-like changes in human neuroblastoma cell line SY-SY5Y in a paracrine manner (2022)
• Interaction of alginate with nano-hydroxyapatite-collagen using strontium provides suitable osteogenic platform (2022)
• Photothermal effect of albumin-modified gold nanorods diminished neuroblastoma cancer stem cells dynamic growth by modulating autophagy (2022)
• The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
• Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells. (2022)
• KANSER HÜCRELERİNDE BIBR1532 VE RESVERATROL KOMBİNASYONUNUN WNT SİNYAL YOLAĞI ÜZERİNDEKİ ETKİLERİ (2022)
• Application of exosomes for the alleviation of COVID‐19‐related pathologies (2022)
• Correction to: The role of the WNT signaling pathway in the maxillary sinus squamous cell carcinoma (2022)
• Chk1/2 inhibitor AZD7762 enhances the susceptibility of IDH-mutant brain cancer cells to temozolomide (2022)
• Targeting UPR signaling pathway by dasatinib as a promising therapeutic approach in chronic myeloid leukemia (2022)
• Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells (2022)

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