Nefise Ülkü KARABAY YAVAŞOĞLU

Fen Fakültesi, Biyoloji Bölümü, Genel Biyoloji Anabilim Dalı

Research areas: Natural Sciences, Health Sciences, Life Sciences, Molecular Biology and Genetics, Moleculer Biology of Cancer, Pharmacology and Therapeutics, Biotechnology, Medicine, Biomaterial, Ecotoxicology

Publications

• Mitochondrial Dynamics-Related Gene Regulation by Epigenetic Suppression of GCN5 Exerts Neuroprotective Effects in Rotenone-Induced Parkinson’s Disease Model (2026)
• CD44 Targeting of Cisplatin-Loaded Hyaluronic Acid-Modified Mesoporous Silica Nanoparticles for Lung Adenocarcinoma: Synthesis, Characterization, In Vitro and In Vivo Evaluation (2026)
• Mitochondrial Dynamics-Related Gene Regulation by Epigenetic Suppression of GCN5 Exerts Neuroprotective Effects in Rotenone-Induced Parkinson’s Disease Model (2026)
• CD44 Targeting of Cisplatin-Loaded Hyaluronic Acid-Modified Mesoporous Silica Nanoparticles for Lung Adenocarcinoma: Synthesis, Characterization, In Vitro and In Vivo Evaluation (2026)
• Post-transcriptional knockdown of BRCC3 via siRNA-loaded niosomes modulates autophagy and endoplasmic reticulum stress in rotenone-induced Parkinson’s Disease model (2026)
• Anti‐Cancer Effect of a New 5‐FU Derivative Containing Triazole‐Bearing Mannose (5‐FUD‐MAN) Against Human Breast Cancer Cells Through LC3B‐Mediated Cell Death (2026)
• Zafirlukast Exacerbates Behavioral Seizure Activity and Blood–Brain Barrier Disruption Despite Modestly Reducing Neuronal Injury Markers in a PTZ-Induced Early Epileptogenesis Mouse Model (2026)
• Protective effect of (±)-gossypol through modulation of VEGF and apoptosis in mice bearing Ehrlich’s solid carcinoma (2026)
• CD44 Targeting of Cisplatin-Loaded Hyaluronic Acid-Modified Mesoporous Silica Nanoparticles for Lung Adenocarcinoma: Synthesis, Characterization, In Vitro and In Vivo Evaluation (2026)
• Dual-drug-loaded magnetic lipid based nanobubbles are effective in non-small cell lung cancer treatment: in vitro and in vivo studies (2025)
• Modulating Cancer Stem Cell Characteristics in CD133+ Melanoma Cells through Hif1α, KLF4, and SHH Silencing (2025)
• Dual-drug-loaded magnetic lipid based nanobubbles are effective in non-small cell lung cancer treatment: in vitro and in vivo studies (2025)
• Effect of miRNA administration on non-small cell lung cancer cells studied by cellular viability assay and ATR-FTIR spectroscopy combined with multivariate data-analysis (2025)
• In Silico and In Vitro Perspectives on the Potential Anticancer Activity and Toxicity of Anticancer Drug Modified with Carbohydrates Containing Novel Triazole Compounds (2025)
• Salvia argentea L. extract inhibits the production of NO, and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), alleviates the inflammatory response of LPS-induced macrophages cells, and reduces the CRP level on carrageenan-induced paw edema (2025)
• Halopteris scoparia Overcomes Cisplatin Resistance and Their Combination Inhibits Lung Adenocarcinoma Tumor Growth: A Study on Cytotoxicity, Cell Cycle, DNA Fragmentation, Membrane Permeabilization, Oxidative Stress, Apoptosis Regulation and IVIS Imaging (2025)
• Extraction of high purity and quality C-phycocyanin with high antioxidant activity from bulk culture biomass of Arthrospira platensis EGE MACC38 (2025)
• Modulating Cancer Stem Cell Characteristics in CD133+ Melanoma Cells through Hif1α, KLF4, and SHH Silencing (2025)
• In Silico and In Vitro Perspectives on the Potential Anticancer Activity and Toxicity of Anticancer Drug Modified with Carbohydrates Containing Novel Triazole Compounds (2025)
• Skin sensitization study of bee venoms collected from honeybee ecotypes from Turkiye and Cyprus (2025)
• DNA damage and oxidative stress responses to pollution of Mytilus galloprovincialis L. from the Izmir Bay (Turkey): Seasonal evaluation (2025)
• Extraction of high purity and quality C-phycocyanin with high antioxidant activity from bulk culture biomass of Arthrospira platensis EGE MACC38 (2025)
• Receptor mediated targeting of EGF-conjugated alginate-PAMAM nanoparticles to lung adenocarcinoma: 2D/3D in vitro and in vivo evaluation (2024)
• Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response (2024)
• Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response (2024)
• Modulating cancer stem cell characteristics in CD133+ melanoma cells through HIF1α, KLF4, and SHH silencing (2024)
• Nonclinical safety assessment of vaccines: Up to date applications (2024)
• Receptor mediated targeting of EGF-conjugated alginate-PAMAM nanoparticles to lung adenocarcinoma: 2D/3D in vitro and in vivo evaluation (2024)
• Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response (2024)
• Nonclinical safety assessment of vaccines: up to date applications (2024)
• The potential usage of cellulose based magnetite-nanocomposite (MAG-CNF) for biomedical applications (2023)
• Effects of 4-phenyl butyric acid (4-PBA), adipose-derived mesenchymal stem cells (ADMSCs), and their combination in the experimental Multiple Sclerosis model (2023)
• Impact of a Polymer-Based Nanoparticle with Formoterol Drug as Nanocarrier System In Vitro and in an Experimental Asthmatic Model (2023)
• Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives (2023)
• Nanočestice L-glutaminske kiseline-g-polihidroksietilnoga metakrilata - Akutna i subakutna toksičnost i bioraspodjela u miševa (2023)
• Preparation, characterization, and toxicity evaluation of microemulsion formulation containing prunetin for potential oral applications (2023)
• Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes (2023)
• Triterpen saponin türü bileşiklerin antioksidan kapasitesi, sitotoksik, genotoksik ve anti-anjiyogenik etkinlikleri (2023)
• Tetrachloromethane Induced Acute Liver Injury in Mice: Biochemical and Histopathological Study of the Hepatoprotective Effect of Hep-X Standardized Botanical Dietary Supplement (2023)
• Tetrachloromethane Induced Acute Liver Injury in Mice: Biochemical and Histopathological Study of the Hepatoprotective Effect of Hep-X Standardized Botanical Dietary Supplement (2023)
• Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats? (2023)
• Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes (2023)
• Exopolysaccharide from Rhodococcus pyridinivorans ZZ47 Strain: Evaluation of Biological Activity and Toxicity (2023)
• Cytotoxicity and Anti-Angiogenic Potential of a Macro Alga, Ulva rigida C. Agardh (Green Alga) from Izmir Bay (Turkey) (2023)
• Polymeric nanoparticles tryptophan-graft-p(HEMA): a study on synthesis, characterization, and toxicity (2022)
• How Safe Is the Use of Intrathecal Vancomycin? (2022)
• Cellular Biomarkers in Mytilus galloprovincialis L. (Mediterranean Mussels) from Izmir Bay (Turkey) (2022)
• Is Losartan a Promising Agent for the Treatment of Type 1 Diabetes-Induced Testicular Germ Cell Apoptosis in Rats? (2022)
• Cytotoxicity and genotoxicity evaluations of oleic acid and conjugated linoleic acid (2022)
• TETRACHLOROMETHANE INDUCED ACUTE LIVER INJURY IN MICE: BIOCHEMICAL AND HISTOPATHOLOGICAL STUDY OF THE HEPATOPROTECTIVE EFFECT OF HEP-X STANDARDIZED BOTANICAL DIETARY SUPPLEMENT (2022)
• Phytochemistry, Biological Activity and Toxicity of Botanical Dietary Supplement: KL21 (2022)
• Butyl Cyclohexyl Phthalate (BCHP) Exposure Induces Oxidative Stress on Male Reproductive System (2022)
• Polymeric nanoparticles tryptophan‑graft‑p(HEMA): a study on synthesis, characterization, and toxicity (2022)
• Butyl Cyclohexyl Phthalate (BCHP) Exposure Induces Oxidative Stress on Male Reproductive System (2022)
• Oxidative stress-induced apoptotic changes after acute exposure to antifouling agent zinc pyrithione (ZnPT) in Mytilus galloprovincialis Lamark (Mediterranean mussels) tissues (2022)
• Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions (2022)
• Butyl Cyclohexyl Phthalate (BCHP) Exposure Induces Oxidative Stress on Male Reproductive System (2022)
• Reconstructed Human Epidermis Model in Assessing of Biocidal Products that Directly Contact the Human Body, Advantages and Disadvantages (2021)
• Subacute effects on mice central nervous system of dimethyl isophthalate (DMIP) (2021)
• Prunetin Inhibits Nitric Oxide Activity, Proliferation and Induces Apoptosis in Urinary Bladder Cancer Cells (RT-4) Through the Enhancement of Apoptotic Pathway via CASP3 and TNF-α Genes That Are Involved (2021)
• PREPARATION AND IN VITRO EVALUATION OF L-LYSINE GRAFTED pHEMA MEMBRANES FOR POTENTIAL USE AS DRUG DELIVERY SYSTEMS (2021)
• Evaluation Of Radiopharmaceutical Potential Of L-Proline- Graft-Poly(Hema) Labeled With 99mtc Using In-Vitro And In-Vivo Assays (2021)
• Cytotoxicity, genotoxicity, total oxidant status and acute oral toxicity potential of Tryptophan-graft-p(HEMA) polymeric nanoparticle in terms of usability as drug carrier (2021)
• Reconstructed Human Epidermis Model in Assessing of Biocidal Products that Directly Contact the Human Body, Advantages and Disadvantages (2021)
• The regulatory effects of clomiphene and tamoxifen on mTOR and LC3-II expressions in relation to autophagy in experimental polycystic ovary syndrome (PCOS) (2021)
• Preparation of a Tc-99m-labeled graft polymer and its in vitro and in vivo evaluation (2021)
• Root extract of Sarcopoterium spinosum (Thorny Burnet) inhibits the cell viability and induces apoptosis through caspase-dependent pathway in human lung cancer cells (2021)
• The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy (2021)
• Prunetin inhibits nitric oxide activity and induces apoptosis in urinary bladder cancer cells via CASP3 and TNF-α genes (2021)
• Giresun Tombul Fındık (Corylus avellana L.) Yağının Serviks, Meme ve Kolon Kanser Hücrelerinde Sitotoksik ve Antianjiyojenik Aktivitesi (2021)
• The influence of locally administered adipose-derived mesenchymal stem cells on nerve homeostasis preservation in mice with diabetic neuropathy (2020)
• Determination of the in vitro biocompatibility potential of hyaluronic acid produced from non-pathogenic bacteriaintended to be used as wound dressing (2020)
• Synthesis, characterization and toxicity assessment of a new polymeric nanoparticle, L-glutamic acid-g-p(HEMA) (2020)
• Apoptosis-inducing activity of safflower (Carthamus tinctorius L.) seed oil in lung, colorectal and cervix cancer cells (2020)
• Ameliorative effect of edible Halopteris scoparia against cadmium-induced reproductive toxicity in male mice: A biochemical and histopathologic study (2020)
• Antibacterial effects of disinfectant containing 10% povidone iodine according to TS EN 1276 (2019)
• Characterization and Biological Activities of C-Phycocyanin Isolated from Spirulina platensis (2019)
• Evalutaion of phthalates toxicity and their effects on reproductive system (2019)
• Subacute effects on male reproductive system of dimethyl isophthalate as endocrine disruptors (2019)
• Evalutaion of phthalates toxicity and their effects on reproductive system (2019)
• Mid-dose losartan mitigates diabetes-induced hepatic damage by regulating iNOS, eNOS, VEGF, and NF-?B expressions (2019)
• Synthesis, characterization, toxicity and in vivo imaging of lysine graft polymeric nanoparticles (2019)
• Mid-dose losartan mitigates diabetes-induced hepatic damage by regulating iNOS, eNOS, VEGF, and NF-κB expressions (2019)
• Antibacterial effects of disinfectant containing 10 % povidone iodine according to TS EN 1276 (2019)
• Autophagy and mTOR pathways in mouse embryonic stem cell, lung cancer and somatic fibroblast cell lines (2019)
• Apoptosis-inducing activities of Halopteris scoparia L. Sauvageau (Brown algae) on cancer cells and its biosafety and antioxidant properties (2019)
• Nano Temelli Pulmoner ilaç taşıma sistemi olarak Lys-g-p(HEMA)-Formoterol (2019)
• Fluvastatin attenuates doxorubicin-induced testicular toxicity in rats by reducing oxidative stress and regulating the blood–testis barrier via mTOR signaling pathway (2019)
• Dual Drug Loaded Solid Lipid Nanoparticles For Glioblastoma Therapy Via Intranasal Route: Toxicological and Pharmacokinetic Studies (2019)
• Streptozotosin’in Karaciğer Üzerindeki Toksik Etkisinin Histokimyasal Değerlendirilmesi (2018)
• Streptozotosin’in Sitotoksik ve Genotoksik Etkileri (2018)
• Biyosidal Ürünlerin Etiket Örneğinde Belirtilen Toksik Riskler ve Değerlendirme Yöntemleri (2018)
• Deneysel Polikistik Over Sendromu (Pkos) Modelinde Tamoksifen Ve Klomifenin Ovaryum Dokusu Üzerine Etkilerinin Otofajik Açıdan Değerlendirilmesi (2018)
• In vitro toxic effects of L-glutamic acid-g-p( HEMA) polymeric nanoparticle (2018)
• Streptozotosin’in Sitotoksik ve Genotoksik Etkileri (2018)
• Deneysel Polikistik Over Sendromu (Pkos) Modelinde Tamoksifen Ve Klomifenin Ovaryum Dokusu Üzerine Etkilerinin Otofajik Açıdan Değerlendirilmesi (2018)
• Investigation of the Effects of Paclitaxel on Cell viability and Glutathion-S-Transferase Enzyme Activities in various cell lines (2018)
• Kahverengi alg Halopteris scoparia Sauvageau ekstraktının in vitro yara iyileştirme ve in vivo anti-anjiyogenik etkisinin belirlenmesi (2018)
• Diyabetin neden olduğu testis hasarı üzerine Losartan’ın olası anti-apoptotik etkisinin araştırılması P046 (2018)
• Doksorubisin İle İndüklenen Sıçan Testis Hasarı Modelinde Fluvastatinin Olası Koruyucu ve Tedavi Edici Etkilerinin Histokimyasal Ve İmmünohistokimyasal Olarak Değerlendirilmesi (2018)

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