Gülperi ÖKTEM
Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji Ve Embriyoloji Anabilim Dalı
Araştırma alanları: Sağlık Bilimleri, Tıp, Temel Tıp Bilimleri, Histoloji-embriyoloji, Temel Bilimler, Yaşam Bilimleri, Dahili Tıp Bilimleri, Moleküler Biyoloji ve Genetik, Kanser Moleküler Biyolojisi, İç Hastalıkları
Yayınlar
- GSK-3 inhibitor induces apoptosis and cell cycle arrest in CD133+/CD44+ prostate cancer cells through modulation of Notch signaling pathway (2025)
- Can mesenchymal stem cell and retinoic acid therapies more effectively reduce lung damage due to bronchopulmonary dysplasia? (2025)
- Megalin (LRP2) Expression Patterns in Prostate Cancer Stem Cells and Metastatic Subtypes: Implications for Tumor Progression and Metabolism (2025)
- Meme kanseri tedavisinde 147-DENA monoklonal antikorunun apoptotik etkisinin incelenmesi (2025)
- Differences and similarities in biophysical and biological characteristics between U87 MG glioblastoma and astrocyte cells (2024)
- A Comprehensive Review of the Mechanisms and Clinical Development of Monoclonal Antibodies in Cancer Therapy (2024)
- Embryonic microenvironment suppresses YY1 and YY1-related genes in prostate cancer stem cells (2024)
- Doxorubicin-induced senescence promotes resistance to cell death by modulating genes associated with apoptotic and necrotic pathways in prostate cancer DU145 CD133+/CD44+ cells (2023)
- İnsan diş pulpası kaynaklı mezenkimal kök hücrelerin meme kanseri kök hücreleri üzerine etkisi (2023)
- Cancer stem cells and nitric oxide (2023)
- Differences and similarities in biophysical and biological characteristics between U87 MG glioblastoma and astrocyte cells (2023)
- Optimized method for using embryonic microenvironment to reprogram cancer stem cells (2023)
- Radiosensitivity of glioblastoma multiforme and astrocytic cell lines in cell signalling aspects (2022)
- 'Double Hit' Strategy: Removal of Sialic Acid from the Dendritic Cell Surface and Loading with CD44+/CD24-/Low Cell Lysate Inhibits Tumor Growth and Metastasis by Targeting Breast Cancer Stem Cells (2022)
- “Double hit” strategy: Removal of sialic acid from the dendritic cell surface and loading with CD44+/CD24-/low cell lysate inhibits tumor growth and metastasis by targeting breast cancer stem cells (2022)
- NK cells in prostate cancer (2021)
- Evaluation of the cancer biology research concept: GBM and astrocyte membrane topology, morphology and chemistry (2021)
- Differences and similarities of biophysical and biological characteristics between GBM and astrocyte cells (2021)
- Neuroprotective Effect of Intrastriatal Caffeic Acid Phenethyl Ester Treatment in 6-OH Dopamine Model of Parkinson’s Disease in Rats (2021)
- Sonic hedgehog signaling is associated with resistance to zoledronic acid in CD133high/CD44high prostate cancer stem cells (2021)
- Cross-talk between ribosome biogenesis, translation, and mTOR in CD133+4/CD44+ prostate cancer stem cells (2020)
- IR spektroskopi kullanılarak in vitro meme kanser kök hücrelerinin araştırılması (2020)
- Effect of Flavopiridol on Cell Cycle, Apoptosis and Biomolecule Structure Changes in Breast Cancer Stem Cells (2020)
- Triptolide inhibits CD133(+)/CD44(+) colon cancer stem cell growth and migration through triggering apoptosis and represses epithelial-mesenchymal transition via downregulating expressions of snail, slug, and twist (2020)
- Evaluation of chondrogenesis and osteogenesis via Wnt/β-Catenin, S100 immunoexpression and histomorphometry in fetal rats following maternal uterine artery ligation (2020)
- Hystotoxicological Examination of A New Design Psychoactive Substance 5-MeO-MiPT (2019)
- Hystotoxicological Examination of A New Design Psychoactive Substance 5-MeO-MiPT (2019)
- Zoledronik asit uygulamasının meme kanseri hücre hattı (MCF 7) kanser kök hücrelerinin üzerine otofaji gen seviyesindeki etkilerinin araştırılması (2019)
- Cancer and Cancer Stem Cells: New Molecular Perspectives (2019)
- Cross-talk between ribosome biogenesis, translation, and mTOR in CD133+ 4/CD44+ prostate cancer stem cells (2019)
- Glycogen synthase kinase-3 inhibition in glioblastoma multiforme cells induces apoptosis, cell cycle arrest and changing biomolecular structure (2019)
- Zoledronik asit uygulamasının meme kanseri hücre hattı (MCF 7) kanser kök hücrelerinin üzerine otofaji gen seviyesindeki etkilerinin araştırılması (2019)
- Differential gene expression analysis of human cumulus cells (2019)
- Characterization of CD133 + /CD44 + human prostate cancer stem cells with ATR-FTIR spectroscopy (2019)
- Zoledronik Asit Uygulamasının Meme Kanseri Hücre Hattı (MCF 7) Kanser Kök Hücrelerinin Üzerine Otofaji Gen Seviyesindeki Etkilerinin Araştırılması P087 (2018)
- Glioblastoma multiforme hücrelerinde glikojen sentaz kinaz-3 inhibisyonunun apoptoz,hücre döngüsü ve biyomoleküler yapı üzerindeki etkisi (2018)
- Ribozom Biyogenezi CD44/CD24- Meme Kanser Kök Hücrelerinde Flavopiridolün Antitümör Etkinliğine Aracılık Eder (2018)
- Triptolide Inhibits Proliferation, Migration and Epithelial–Mesenchymal Transition by Modulation Snail, Slug and Twist Expression in CD133/CD44 Colon Cancer Stem Cell (2018)
- Zoledronic acid overcomes chemoresistance by sensitizing cancer stem cells to apoptosis (2018)
- FLUVASTATİNİN TAVŞAN KAROTİD ARTERİ YAKA MODELİNDE İNTİMAL KALINLAŞMA ÜZERİNE ETKİLERİ (2018)
- EMG, MAPK ve inflamasyona yakından bakış: Fare embriyonik kök hücre, somatik ve kanser hücrelerinde ne farklıdır? (2018)
- Prostat Kanseri Kök Hücre Kültürü İle Kök Hücre içermeyen Prostat Kanseri Hücre Kültüründe MTOR ve MLST8 moleküllerinin İmmunoflorans yöntemi ile karşılaştırılması. (2018)
- Radyosensitivitenin Glioblastoma multiforme ve Astrositik Hücre Hatlarının Hücre Sinyalizasyonlarına Etkisi P092 (2018)
- Effects of sunitinib on immunoreactivity of vimentin, E-cadherin and S100 in kidneys of streptozotocin induced diabetic mice. (2018)
- E ects of di erent drug treatments on the proliferation of human ovarian carcinoma cell line MDAH-2774 (2018)
- Close look in EMT, MAPK and inflammation: what differs in mouse embryonic stem, somatic and cancer cells? (2018)
- Expressional assessment of mouse embryonic stem cell, lung cancer and somatic fibroblast cell lines on the basis of EMT, MAPK and Inflammation (2017)
- Expressional assessment of mouse embryonic stem cell, lung cancer and somatic fibroblast cell lines on the basis of EMT, MAPK and Inflammation. (2017)
- Radiosensitivity of Glioblastoma Multiforme Cell Line in Cell Signalling Aspects. Advances in Stem Cells and Regenerative Medicine (2017)
- Stem cell-induced di erential gene expression pro les associated with apoptosis, necrosis and anoikis: Novel insights into cell death mechanisms in prostate cancer (2017)
- Insignificant association between megalin expression in prostate cancer tissue and prostate cancer stem cells (2017)
- The effects of sunitinib on immunoreactivities of vimentin, E-cadherin and S100 in kidneys of the experimental Streptozotocin -induced mouse model (2017)
- Radiosensitivity of Glioblastoma Multiforme Cell Line in Cell Signalling Aspects (2017)
- The Autophagic Activity of Lithium Chloride on Different Tumor Cell Lines UsingElectron Microscopy (2017)
- Assessment of mTOR pathway molecules during implantation in rats (2017)
- Rab23 expression in prostate cancer stem cell (2017)
- Compairment of autophagy and mTOR pathways in mouse embryonic stem cell, lung cancer and somatic fibroblast cell lines in molecular analysis base. (2017)
- Expression of the bone morphogenetic protein-2 (BMP2) in the human cumulus cells as a biomarker of oocytes and embryo quality (2017)
- Deneysel Diyabet Modeli Oluşturulan farelerde tirozin kinaz inhibitör uygulanımının testis dokusu üzerine olan etkilerinin pluripotensi kapasitesi ve hücre adezyonu özelinde araştırılması (2017)
- Deneysel diabet modeli oluşturulan farelerde tirozin kinaz inhibitör uygulanımının testis dokusu üzerine olan etkilerinin pluripotensi kapasitesi ve hücre adezyonu özelinde araştırılması (2017)
- The effects of sunitinib on immunoreactivities of vimentin, E-cadherin and S100 in kidneys of the experimental Streptozotocin -induced mouse model. (2017)
- Repression of the Notch pathway prevents liver damage in streptozotocin-induced diabetic mice (2017)
- Ribosome biogenesis mediates antitumor activity of flavopiridol in CD44+/CD24‑ breast cancer stem cells (2017)
- Treatment with milk thistle extract (Silybum marianum), ursodeoxycholic acid, or their combination attenuates cholestatic liver injury in rats: Role of the hepatic stem cells (2017)
- Prostate Embryology and Postnatal Development (2017)
- Comparison of cell cycle components apoptosis and cytoskeleton related molecules and therapeutic effects of flavopiridol and geldanamycin on the mouse fibroblast lung cancer and embryonic stem cells (2016)
- Streptozotocin ile İndüklenmiş Diyabetik Farelerde Sunitinib ile Notch Yolağı'nın Baskılanması Karaciğer Hasarını Engeller (2016)
- Effect of High Dose Zoledronic Acid Treatment in Prostate Cancer Stem Cells (2016)
- JAK/STAT pathway interacts with intercellular cell adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM) while prostate cancer stem cells form tumor spheroids. (2016)
- Kanser Kök Hücrelerinde Otofaji İlişkili Gen Ekspresyon Analizi (2016)
- Ege Üniversitesi Kök Hücre Anabilim Dalılisansüstü eğitim deneyimi (2016)
- Fare fibroblast, fare akciğer kanseri ve fare embriyonik kök hücrelerinde flavopiridol ve geldanamisinin terapötik etkilerinin ve hücre döngüsü bileşenleri, apopitozis, hücre iskeleti ilişkili moleküllerin karşılaştırılması. (2016)
- Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells (2016)
- Fare Akciğer Yassı Hücreli Kanserinde, Hücre Stabilizasyonu Ve Epiteliyal- Mezenkimal Geçiş Üzerine Flavopiridol Etkilerinin Araştırılması (2016)
- Kök Hücre ve Kanser Kök Hücreleri (2016)
- Flavopiridolün Hücre Döngüsü, Hücre İskeleti, Polarite Ve Apopitoz Özelinde Cd133high/Cd44high Akciğer Kanseri Kök Hücreleri Üzerindeki Etkileri (2016)
- Prostat Kanser Kök Hücresi ve Embriyo Ortak Kültürlerinde Yeniden Programlanmanın Epiteliyal Mezenşimal Değişim Yönüyle Araştırılması. (2016)
- Lithium chloride has a biphasic effect on prostate cancer stem cells and a proportional effect on midkine levels (2016)
- Medium modification with bone morphogenetic protein 2 addition for odontogenic differentiation (2016)
- Comparison of cell cycle components, apoptosis and cytoskeleton-related molecules and therapeutic effects of flavopiridol and geldanamycin on the mouse fibroblast, lung cancer and embryonic stem cells (2016)
- In vivo performance of different scaffolds for dental pulp stem cells induced for odontogenic differentiation (2016)
- Effect of complete hilar versus only renal artery clamping on renal histomorphology following ischemia/reperfusion injury in an experimental model (2016)
- Investigation of the Cell Stabilization and the Epithelial to Mesenchymal Transition Effect of Flavopiridol in Mouse Lung Squamous Cell Carcinoma. (2016)
- JAK STAT pathway interacts with intercellular cell adhesion molecule ICAM and vascular cell adhesion molecule VCAM while prostate cancer stem cells form tumor spheroids (2015)
- Deneysel tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi (2015)
- Deneysel tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi (2015)
- Deneysel tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi (2015)
- Kök Hücre ve Kanser Kök Hücresi (2015)
- Deneysel tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi (2015)
- Development of a Three dimensional 3D Breast Tumour Model Using Cancer Stem Cells (2015)
- Deneysel Tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi 2015 54 1 19 25 (2015)
- Enhanced G2/M Arrest, Caspase Related Apoptosis and Reduced E-Cadherin Dependent Intercellular Adhesion by Trabectedin in Prostate Cancer Stem Cells (2015)
- Investigation of the Cell Stabilization and the Epithelial to Mesenchymal Transition Effect of Flavopiridol in Mouse Lung Squamous Cell Carcinoma (2015)
- Deneysel tirotoksikoz modelinde sıçan ovaryum dokusu rejenerasyon yeteneği ve kapasitesi Thyrotoxicosis in experimental rat model of ovarian tissue regeneration capability and capacity (2015)
- A potential Bioactive Method for Dental Tissue Engineering (2014)
- A Potential Bioactive Method for Dental Tissue Engineering (2014)
- Şirin Baktı Demiray Özlem Yılmaz Dilsiz Ege Nazan Tavmergen Göker Erol Tavmergen Nilüfer Çalımlıoğlu Gülperi Öktem Kumulus hücrelerinin genetik yapısının ve AMH BMP2 CD90 THY1 immunfloresan belirteçleri ile ilişkisinin ICSI başarısı üzerine etkileri Sözlü sunu XI Ulusal Histoloji ve Embriyoloji kongresi Ankara 27 30 Mayıs 2014 (2014)
- Odontojenik Rejenerasyon Mümkün mü? (2014)
- Altered Stem Cell Receptor Activity in the Ovarian Surface Epithelium by Exogenous Zinc and or Progesterone (2014)
- Experimental remodellation of extracorporeal irradiated autogenous and allogenic patellar grafts (2014)