BAKİYE GÖKER BAĞCA
Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Anabilim Dalı
Research areas: Health Sciences, Medicine, Medical Biology, Fundamental Medical Sciences, Life Sciences, Natural Sciences, Molecular Biology and Genetics, Internal Medicine Sciences, Cytogenetic, Moleculer Biology of Cancer
Publications
- The impact of inhibiting the Hippo signaling pathway effectomolecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
- Correction: The impact of inhibiting the Hippo signaling pathway effector molecule YAP1 on in vitro glioblastoma and glioblastoma stem cells (2026)
- Temozolomide and ruxolitinib combination modulates miRNA-associated regulatory networks in glioblastoma stem cells (2026)
- Precision oncology: Using cancer genomics for targeted therapy advancements (2025)
- Defeating miR-181a-3p may potentiate the effect of paclitaxel on G2/M arrest in breast cancer stem cells (2025)
- Anti-miRNA- 155 - 5p enhances the cytotoxic efficacy of temozolomide in brain cancer stem cells (2025)
- PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2025)
- Elucidating the genetic mechanism of anti-cancer efficacy of prednisolone in acute lymphoblastic leukemia through anti-miRNA treatments (2025)
- Propofol orchestrates long non-coding RNAs in MCF7 cells, unraveling new avenues for breast cancer intervention (2024)
- PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2024)
- Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications (2024)
- Machine learning in oncological pharmacogenomics: advancing personalized chemotherapy (2024)
- Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases (2024)
- The future of cancer therapy: exploring the potential of patient-derived organoids in drug development (2024)
- Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids (2023)
- Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri (2023)
- Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri (2023)
- Molecular Aspect of Propofol's Effect on Cytotoxic and Long Non-Coding RNA (lncRNA) Expressions in MCF-7 (2023)
- Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes (2022)
- Meme kanseri hücrelerinde anastaz fenomeninin tanımlanması (2022)
- A drug-responsive multicellular human spheroid model to recapitulate drug-induced pulmonary fibrosis (2022)
- The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
- Ponatinib ve Türkiye’de yetişen bazı endemik bitki ekstrelerinin kombinasyonlarının meme kanseri hücreleri üzerindeki etkileri (2022)
- Investigation of Cytotoxic and Apoptotic Effects of Disodium Pentaborate Decahydrate on Ovarian Cancer Cells and Assessment of Gene Profiling (2022)
- Adipose Tissue Mesenchymal Stem Cells Exposed To Oxytocin and Sunitinib are Synergistically Dystrophic (2022)
- INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS (2022)
- Investigating the Effects of a Synthetic Cannabinoid on the Pathogenesis of Leukemia and Leukemic Stem Cells: A New Therapeutic Approach (2022)
- Evaluation of therapeutic effects of KC7F2, temozolomide, and its combination on genes involved in the Wnt signal pathway in the U87MG glioma cell line (2022)
- Adipose Tissue Mesenchymal Stem Cells Exposed To Oxytocin and Sunitinib are Synergistically Dystrophic (2022)
- Investigation of cytotoxic and apoptotic effects of disodium pentaborate decahydrate on ovarian cancer cells and assessment of gene profiling (2022)
- Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells. (2022)
- Combinational effects of ponatinib and some Turkish endemic plant extracts on breast cancer cells (2022)
- Noncoding way of the metastasis (2022)
- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation (2022)
- Future Perspectives of Phytochemicals in Cancer Therapy (2022)
- The Evaluation of the Relationship of Klotho and Telomerase in Obese Patients. (2022)
- Origanum Sipyleum Methanol Extract in Combination with Ponatinib Shows Synergistic anti-Leukemic Activities on Chronic Myeloid Leukemia Cells (2022)
- Interaction of alginate with nano-hydroxyapatite-collagen using strontium provides suitable osteogenic platform (2022)
- Photothermal effect of albumin-modified gold nanorods diminished neuroblastoma cancer stem cells dynamic growth by modulating autophagy (2022)
- Hücre Ayırma Stratejileri (2022)
- Hücre Ölümünün Tersine Çevrilmesi: Anastaz (2022)
- Chapter 6 - Noncoding way of the metastasis (2022)
- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation (2022)
- Future Perspectives of Phytochemicals in Cancer Therapy (2022)
- Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells. (2022)
- Comparative expression analysis of dasatinib and ponatinib-regulated lncRNAs in chronic myeloid leukemia and their network analysis (2022)
- The role of the WNT signaling pathway in the maxillary sinus squamous cell carcinoma (2022)
- Ponatinib miRNA ifadelerini düzenleyerek meme kanseri hücrelerini hedefler (2021)
- Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line (2021)
- Role of inflammatory biomarkers in nephropathy and atherosclerosis in type 2 diabetes mellitus patients with microalbuminuria (2021)
- Investigation of Effects of Synthetic Cannabinoids on The Pathogenesis of Leukemia and Stem Cells (2021)
- P-213 OBEZ HASTALARDA KLOTHO VE TELOMERAZ ILIŞKISININ DEĞERLENDIRILMESI (2021)
- Role of inflammatory biomarkers in nephropathy and atherosclerosis in type 2 diabetes mellitus patients with microalbuminuria (2021)
- In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells (2021)
- Antileukemic Effects of Anti-miR-146a, Anti-miR-155, Anti-miR-181a, and Prednisolone on Childhood Acute Lymphoblastic Leukemia. (2021)
- Analysis of Our Molecular Profiling Results in Patients with Relapsed / Refractory Tumors (2021)
- Sonic hedgehog signaling is associated with resistance to zoledronic acid in CD133high/CD44high prostate cancer stem cells (2021)
- Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs (2021)
- Whole Genome microRNA Expression Data in Childhood Acute Lymphoblastic Leukemia and Evaluation of microRNA Pathways Using Fuzzy C-means (2021)
- Effect of valproic acid on miRNAs affecting histone deacetylase in a model of anaplastic thyroid cancer (2021)
- Anastasis in Glioblastoma, Brain Cancer Stem, and Brain Stem Cells (2021)
- Designing of the Primers and Probes for Real Time Polymerase Chain Reaction of Cytochrome B Gene Region in Leishmaniasis: A Pilot Study (2020)
- PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis (2020)
- PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis (2020)
- Combination of Salinomycin and AZD3463 Reveals Synergistic Effect on Reducing the Viability of T98G Glioblastoma Cells (2020)
- Temozolomide treatment combined with AZD3463 shows synergistic effect in glioblastoma cells (2020)
- Telomerase inhibition regulates EMT mechanism in breast cancer stem cells (2020)
- Targeting TdT gene expression in Molt-4 cells by PNA-octaarginine conjugates (2020)
- Ruxolitinib Regulates the Autophagy Machinery in Multiple Myeloma Cells (2020)
- PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis (2020)
- AZD3463’ÜN BCSC Ve BSC’DE Apoptoz Ve Hücre Döngüsü Üzerindeki Etkileri. (2020)
- The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19 (2020)
- High Glucose Content Abrogated the Normal Activity of Heat Shock Protein Signaling Pathway in Human Neuroblastoma Cells (2020)
- Kronik MiyeloidLösemide DasaOnib V e PonaOnib Aracılı Lncrna Ekspresyon Değişimlerinin Karşılaş?rması. (2019)
- Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the Same Coin (2019)
- Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the Same Coin (2019)
- Kronik Miyeloid Lösemide Dasatinib Ve Ponatinib AracılılncRNA Ekspresyon Değişimlerinin Karşılastırılması (2019)
- Comparative effects of Dasatinib and Ponatinib on lncRNAexpression in Chronic Myeloid Leukemia (2019)
- DEVELOPMENT OF PACLITAXEL-PAMAM G5 CONJUGATE TOOVERCOME MULTIDRUG RESISTANCE OF OVARIAN CANCER CELL LINE MDAH 2774 (2019)
- Comparative effects of Dasatinib and Ponatinib on lncRNA expression in Chronic Myeloid Leukemia (2019)
- Combination of AZD3463 and salinomycin can induce apoptosis and cell cycle arrest on glioblastoma multiform cells (2019)
- Combination of AZD3463 and salinomycin can induce apoptosis and cell cycle arrest on glioblastoma multiform cells (2019)
- EVALUATING THE EFFECT OF KC7F2, THE HIF-1? INHIBITOR, ON GLUCOSE METABOLISM IN U87MG GLIOMA CELL LINE (2019)
- Epigallokateşin-3- gallat uygulamasına bağlı olarak kronik miyeloid lösemi hücrelerinde genetik ve epigenetik otofaji regülatörlerinin ekspresyon değişimlerinin değerlendirilmesi (2019)
- Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the Same Coin. (2019)
- Mikroalbüminürisi olan ve olmayan tip 2 diyabetik hastalarda serum asimetrik dimetil arjinin, fetuin-A ve ankle-brakial indeks değerlerinin değerlendirilmesi (2019)
- Effects of telomerase inhibitor on epigenetic chromatin modification enzymes in malignancies (2018)
- Cancer Stem Cells and Autophagy: PresentKnowledge and Future Perspectives (2018)
- Cancer Stem Cells and Autophagy: Present Knowledge and Future Perspectives (2018)
- Investigation of the effect of MET gene expression alteration on oral cavity tumors (2018)
- THE ROLE OF THE AUTOPHAGY-RELATED GENES IN PARANASAL SQUAMOUS CELL CARCINOMA WITH AND WITHOUT NECK METASTASIS (2018)
- Synergistic effect of ponatinib and epigallocatechin-3-gallate induces apoptosis in chronic myeloid leukemia cells through altering expressions of cell cycle regulatory genes. (2018)
- Docosahexaenoic acid reversed atherosclerotic changes in human endothelial cells induced by palmitic acid in vitro (2018)
- Docosahexaenoic acid attenuates the detrimental effect of palmitic acid on human endothelial cells by modulating genes from the atherosclerosis signaling pathway (2018)
- Heat shock protein 70 modulates neural progenitor cells dynamics in human neuroblastoma SH‐SY5Y cells exposed to high glucose content (2018)
- The Apoptotic Effect of Dabrafenib and Epigallocatechin-3-gallate Combination on Anaplastic Thyroid Cancer Cells (2018)
- PHİLADELPHİA POZİTİF KML OLGULARINDA JAK2 V617FMUTASYONUNUN PREVALANSI (2018)
- ASTIMDA BİYOBELİRTEÇLER OLARAK KAN MİKRORNA’LARININ VE EKSALE VOLATİL ORGANİK BİLEŞİKLERİNİN ÖNEMİ (2018)
- Epigenetic modifications in chronic myeloid leukemia cells through ruxolitinib treatment (2018)
- Low-level laser irradiation at a high power intensity increased human endothelial cell exosome secretion via Wnt signaling (2018)