Elimination of Multi-drug Resistant Acinetobacter baumannii Strain with Various Porphyrin Derivatives Stimulated by Red Light
Conference paper > Full Text · 2018
Authors: Ayse Akbiyik, Hüseyin TAŞLI, Nermin Topaloglu, Vildan ALPTÜZÜN, Sulunay Parlar, Selcuk Kaya
2018 Medical Technologies National Congress (TIPTEKNO), Turkish Republic of Northern Cyprus, International, Verbal, Full Text, 2018-2018, WoS, pp 1-4
DOI: 10.1109/tiptekno.2018.8596962
Summary
In the study, it was aimed to investigate the photoinactivation effect of antimicrobial photodynamic therapy (aPDT) performed on in-vitro conditions with cationic-porphyrin derivatives (CPDs) on multidrug resistant (MDR) A. baumannii. In aPDT experiments using different photosensitizer concentrations and different energy densities, the reduction in bacterial survival reached to > 6 log10 values. aPDT carried out with CPDs at concentrations below the minimum inhibitory concentration (MIC) values has the potential to display a strong antimicrobial activity against the MDR A. baumannii clinical isolate.