In vitro anti-Trichomonas vaginalis activity of Haplophyllum myrtifolium
Articles > Article · 2019
Authors: Asegul Aksoy Gokmen, Hüseyin CAN, Hüsniye KAYALAR, Bayram Pektas, Selcuk Kaya
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, Journal Indexed in SCI Expanded, International, 2019, vol 13, pp 240-244
DOI: 10.3855/jidc.10854
Summary
Introduction: In the classic treatment of Trichomonas vaginalis infection, although metronidazole has been used since the 1960s, there has been an increase in MTZ-resistant T. vaginalis strains and failure in the treatment of trichomoniasis causes serious concerns. Therefore, the present study aimed to investigate the in vitro antitrichomonal activities of extracts (ethanol and total alkaloid) and pure compounds (chrysosplenetin, dictamnine, gamma-Fagarine, skimmianine) of H. myrtifolium against T. vaginalis.