Hüseyin CAN

Fen Fakültesi, Biyoloji Bölümü, Moleküler Biyoloji Anabilim Dalı

Research areas: Parasitology, Health Sciences, Medicine, Natural Sciences, Fundamental Medical Sciences, Life Sciences, Microbiology, Biotechnology, Immunology, Molecular Biology and Genetics

Publications

In vitro expression and seroreactivity of Toxoplasma gondii GRA1 protein encoded by unmodified and nucleoside-modified mRNA constructs (2026)
Molecular prevalence of Wolbachia endosymbiont in fleas (Ctenocephalides felis) collected from goats in Türkiye (2026)
An ELISA Using a T. gondii GRA6-Derived Peptide as Antigen Successfully Detected Ovine Toxoplasmosis (2026)
Comparison of the efficacy of cell wall disruption methods for Saccharomyces cerevisiae INVSc1 cells expressing Toxoplasma gondii recombinant ROP6 protein (2026)
A six-proline stabilized trimeric spike DNA vaccine induces robust immunity and protects against SARS-CoV-2 delta challenge in K18-hACE2 transgenic mice (2026)
Genetic characterization of the Prion Protein Gene in the indigenous Nguni cattle breed of the Kingdom of Eswatini (2025)
Screening for SARS-CoV-2 in different sheep and goat breeds in Türkiye using in-house ELISAs and real-time PCR (2025)
An optimized ROP6 mRNA construct successfully expressed immunogenic Toxoplasma gondii ROP6 protein in cell culture (2025)
DNA Vaccines, an Innovative Vaccine Platform against COVID-19 (2025)
Molecular prevalence and genetic characterization of Enterocytozoon bieneusi in cattle in a dairy farm in Türkiye (2025)
Molecular Investigation of Anaplasma spp. and Genotype Profile of A. ovis in Sheep from Different Farms in Türkiye (2025)
In silico identification of Leishmania GP63 protein epitopes to generate a new vaccine antigen against leishmaniasis (2025)
Recombinant ROP6 protein expressed in Saccharomyces cerevisiae INVSc1 cells induced strong immune response and provided significant protection against toxoplasmosis (2025)
Exploring the Therapeutic Potential of Bee Venom: Computational Analysis of Molecular Interactions with Cellular Targets (2025)
Toksoplazmozise Karşı Multivalan mRNA Aşısı Geliştirilmesi (2024)
DENDRİTİK HÜCRE BAZLI AŞILAR: MEKANİZMALAR, ALT TİPLER VE KLİNİK UYGULAMALAR (2024)
IMMUNOGENICITY ANALYSIS OF EPITOPES DERIVED FROM BARTONELLA HENSELAE LEMA, MOPA AND VCEA PROTEINS (2024)
TOXOPLASMA GONDII MIC17A PROTEİNİN AŞI VE SEROLOJİK TANIDA ÖNEMİ OLAN EPİTOP BÖLGELERİNİN IN SILICO KEŞFİ (2024)
Development of a Novel GRA8 DNA Vaccine to Prevent Toxoplasma gondii Infection in Sheep- (2024)
Memeli Süspanse HEK293F Hücrelerde Aşı Adayı Toxoplasma gondii GRA1 ve ROP6 Rekombinant Proteinlerinin Ekspresyonu, Saflaştırılması ve İmmünojenisitesi (2024)
PNEUMOCYSTİS JİROVECİİ TANISI İÇİN HIZLI KOLORİMETRİK LAMP TESTİNİN GELİŞTİRİLMESİ VE ANALİTİK DUYARLILIĞIN BELİRLENMESİ (2024)
Mitotyping of random bred cats and pure breed cats (Turkish Angora and Turkish Van) using non-repetitive mitochondrial DNA control region (2024)
Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against Anaplasma ovis using immunoinformatic tools (2024)
Development of a "Rapid-Crypto Colorimetric LAMP Test" to Detect Cryptosporidiosis in Feces of Newborns Calves (2024)
Genetic characterization of Toxoplasma gondii strains isolated from humans living in ˙ Izmir, Türkiye (2024)
Vaccine antigen discovery: a breakthrough in genomic era (2024)
Dışkı Örneklerinin İncelenmesi (2024)
Computational identification of monkeypox virus epitopes to generate a novel vaccine antigen against Mpox (2024)
Vaccine antigen discovery: a breakthrough in genomic era (2024)
Author Correction: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts (2024)
Computational Analysis Shows Strong Interactions between Snake Venom Molecules and Cell Receptors (2024)
First report of a novel 108 bp deletion and five novel SNPs in PRNP gene of stray cats and in silico analysis of their possible relation with feline spongiform encephalopathy (2024)
Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production (2024)
A novel DNA vaccine encoding the SRS13 protein administered by electroporation confers protection against chronic toxoplasmosis (2024)
Molecular prevalence and genotypes of Enterocytozoon bieneusi in cancer patients under chemotherapy in Aegean region of Türkiye (2024)
Newly developed peptide-ELISA successfully detected anti-IgG antibodies against Maedi-Visna virus in sheep (2024)
Molecular prevalence of Enterocytozoon bieneusi in stray cats of İzmir, Türkiye (2023)
Molecular prevalence and genetic diversity of Hepatozoon spp. in stray cats of İzmir, Türkiye (2023)
Genotyping of Enterocytozoon bieneusi isolates detected in stray cats of İzmir, Türkiye (2023)
Development and Sensitivity Determination of 18S rRNA Gene-specific Fast Loop-mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of Acanthamoeba (2023)
Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
A preliminary study to develop a lateral flow assay using recombinant GRA1 protein for the diagnosis of toxoplasmosis in stray cats (2023)
Applicability evaluation of mtDNA based molecular identification in mosquito species/subspecies/biotypes collected from Thessaloniki, Greece (2023)
In silico discovery of epitopes of gag and env proteins for the development of a multi-epitope vaccine candidate against Maedi Visna Virus using reverse vaccinology approach (2023)
A preliminary study to develop a lateral flow assay using recombinant GRA1 protein for the diagnosis of toxoplasmosis in stray cats (2023)
Aşı Antijen Keşfi (2023)
Aşı Geliştirmede Biyoinformatik ve İmmünoinformatik (2023)
mRNA Aşıları (2023)
Toxoplasma gondii ROP6 mRNA Aşı Transkriptlerinin Üretimi ve Rekombinant ROP6 Protein İmmünojenisitesi (2023)
Leishmania infantum DNA Aşısı Adayı Gp63 Proteinin in silico Analizi (2023)
Toxoplasma gondii’nin Her Üç Dönemine Karşı Etkili MIC3 Proteininin Saccharomyces cerevisiae Tabanlı Rekombinant Protein Aşı Stratejisinde Kullanılması Amacıyla in silico Analizlerinin Gerçekleştirilmesi (2023)
Immunogenicity and Protective Efficacy of A Novel DNA Vaccine Expressing Toxoplasma gondii SRS13 Protein Against Chronic Toxoplasmosis (2023)
Toksoplazmozise Karşı DNA Aşısının Geliştirilmesi (2023)
An In house ELISA using recombinant GRA1 and BAG1 proteins as antigen successfully detected Toxoplasma gondii infection in a flock of sheep suffering from abortions (2023)
Genetic characterization of Bartonella henselae samples isolated from stray cats by multi-locus sequence typing (2023)
Molecular and bioinformatics evaluation of PRNP as a candidate gene for successful suicidal behavior (2023)
Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
The Importance of Vaccines in a Sustainable Healthy Society (2023)
The Importance of Vaccines in a Sustainable Healthy Society (2023)
An Investigation into The Frequency and Causes of Fleas in Goat Farms (2023)
Molecular Prevalence of Enterocytozoon Bieneusi in Stray Cats of İzmir, Türkiye (2023)
Importance of screening severe COVID-19 patients for IFN-λ1, IL-6 and anti-S1 IgG levels (2023)
Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in ?Izmir and S , anl?urfa provinces of Turkey (2022)
Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in ?Izmir and S , anl?urfa provinces of Turkey (2022)
Immunogenicity of a xenogeneic multi-epitope HER2+breast cancer DNA vaccine targeting the dendritic cell restricted antigen-uptake receptor DEC205. (2022)
Designing DNA vaccines with immuno-informatics tools (2022)
mRNA Vaccines against Parasitic Infections (2022)
Vaccines against Parasitic Infections (2022)
Molecular prevalence of Blastocystis sp. and subtype diversity in fecal samples collected from cattle in dairy farms in Turkey (2022)
Molecular investigation of Blastocystis sp. and its subtypes in cancer patients under chemotherapy in Aegean region, Turkey (2022)
Molecular prevalence and genetic diversity of Bartonella spp. in stray cats of İzmir, Turkey (2022)
Development of multistage recombinant protein vaccine formulations against toxoplasmosis using a new chitosan and porin based adjuvant system (2022)
Investigation of Genetic Diversity of Toxoplasma gondii Strains Isolated from Poultry and Toxoplasmosis Seroprevalance (2022)
Investigation of Echinococcus granulosus and Echinococcus multilocularis frequency in patients administered to Ege University Faculty of Medicine Molecular Parasitology Laboratory between 2007-2019 using multiplex real-time PCR targeting 12s rRNA gene (2022)
Toxoplasma gondii’ye Karşı Geliştirilen DNA Aşılarına Genel Bir Bakış (2022)
Toksoplazmozise Karşı Geliştirilen Biyoteknolojik Tabanlı Rekombinant Protein Aşıları (2022)
mRNA aşılarının etkinliğinin arttırılması: sentetik mRNA tasarımı (2022)
T. gondii GRA8 DNA Vaccines (2022)
In silico vaccine design against influenza A and B viruses (2022)
A novel stabile trimeric vaccine antigen against the wild type SARS COV-2 and Delta variant (2022)
A novel approach for in silico design of DNA vaccine candidate against latent Toxoplasmosis (2022)
Bioinformatics analysis and protein production of recombinant protein vaccine against Toxoplasma gondii. (2022)
Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against Anaplasma ovis using immunoinformatic tools (2022)
Investigation of the Genetic Diversity and Flea-Borne Pathogens in Ctenocephalides Felis Samples Collected from Goats in İzmir and Şanlıurfa Provinces of Turkey (2022)
Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in İzmir and Şanlıurfa provinces of Turkey (2022)
Ege Üniversitesi Tıp Fakültesi Hastanesinde Toksoplazmozis Sıklığının Real-Time PZR ile Belirlenmesi (2022)
Rapid detection of Toxoplasma gondii DNA in cat feces using colorimetric loop-mediated isothermal amplification (LAMP) assays targeting RE and B1 genes (2022)
Molecular prevalence and subtyping of Cryptosporidium spp. in fecal samples collected from stray cats in İzmir, Turkey. (2022)
Low frequency of protective variants at regulatory region of PRNP gene indicating the genetically high risk of BSE in Ethiopian Bos indicus and Bos taurus africanus (2022)
Development of a new serotyping ELISA for Toxoplasma gondii type II, type III and Africa 1 lineages using in silico peptide discovery methods, well categorized feline and human outbreak serum samples (2022)
Administration of Four Different COVID-19 pcDNA 3.1 DNA Vaccine Prototypes Using Intradermal Electroporation and Assessment of Their Immunogenicity in BALB/c mouse (2021)
mRNA aşıları (2021)
İzmir İli Sokak Kedilerinden Toplanan Dışkı Örneklerinde Cryptosporidium spp.'nin Polimeraz Zincir Reaksiyonu Yöntemi ile Araştırılması ve Alt Tiplendirilmesi (2021)
Cryptosporidiosis outbreak on a dairy farm: Detection of Cryptosporidium parvum as a causative agent in the water source (2021)
Keçilerden Toplanan Kedi Pirelerinin (Ctenocephalides felis) Genetik Çeşitliliğinin COX1 Gen Analizi ile Araştırılması (2021)
Molecular prevalence and subtyping of Blastocystis sp. isolates in stray cats of İzmir, Turkey: First report of “ST4 allele 42” in cats (2021)
Breast Cancer Vaccines current status and future approach (2021)
Construction of a multiepitope vaccine candidate against Fasciola hepatica: an in silico design using various immunogenic excretory/secretory antigens (2021)
Toxoplasma gondii RE ve B1 Genlerini Hedefleyen Kolorimetrik LAMP Testlerinin Geliştirilmesi ve PCR ile Doğrulanmış Kedi Dışkı DNA Örneklerinde Performanslarının Karşılaştırılması (2021)
Administration of Four Different COVID-19 pcDNA 3.1 DNA Vaccine Prototypes Using Intradermal Electroporation and Assessment of Their Immunogenicity in BALB/c mouse (2021)