Ayçiçek Küspesinden Elde Edilen Protein Hidrolizatlarının Anjiyotensin Dönüştürücü Enzim ve Dipeptidil Peptidaz–IV İnhibisyon Aktiviteleri
Makaleler > Tam Makale · 2022
Yazarlar: Şebnem ŞİMŞEK
Turkish Journal of Agriculture - Food Science and Technology, Diğer Kurumların Hakemli Dergileri, Uluslararası, TR Dizin (Ulakbim), 2022, cilt 10, ss 918-924
DOI: 10.24925/turjaf.v10i5.918-924.4959
Özet
In this study, the potential of sunflower protein hydrolysates to inhibit angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) enzyme was determined. Sunflower protein isolate was hydrolyzed with Alcalase and Trypsin+Chymotrypsin enzymes and the obtained protein hydrolysates were fractionated by ultrafiltration (5 kDa). The degrees of hydrolysis achieved by Alcalase and Trypsin+Chymotrypsin enzymes were 27% and 13%, respectively. The most potent ACE inhibitory activity (IC50=0.06 ± 0.01 mg/mL) was observed for the fraction that has molecular weight below 5 kDa, which was hydrolyzed by Trypsin+Chymotrypsin enzyme (P