Relapsing polychondritis in a child with common variable immunodeficiency
Makaleler > Tam Makale · 2009
Yazarlar: Neslihan KARACA, Güzide AKSU, Basak YILDIZ, Nesrin GULEZ, Bengu Turk, Tugrul DERELI, Necil KÜTÜKÇÜLER
International Journal of Dermatology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2009, cilt 48, ss 525-528
DOI: 10.1111/j.1365-4632.2009.03809.x
Özet
Common variable immunodeficiency (CVID) is associated with recurrent infections and autoimmunity. The most common autoimmune conditions are idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, chronic arthritis, and gastrointestinal inflammation. Relapsing polychondritis (RP) is an episodic and progressive systemic inflammatory disease, characterized by auricular chondritis, polyarthritis, nasal, and respiratory tract chondritis. Autoimmunity to cartilage-related components is thought to be involved in its pathogenesis. So far, RP has not been included within many autoimmune conditions that have been reported in patients with either CVID or any other primary immunodeficiency. In this report, a case of CVID with RP and chronic arthritis is presented.