Serum 8-OHdG and HIF-1 alpha levels: do they affect the development of malignancy in patients with hypoactive thyroid nodules?
Articles > Article · 2013
Authors: H Ece, Mehmet ERDOĞAN, Çığır BİRAY AVCI, D Yavuz, K Muammer, G Cumhur, H Mustafa, C Sevki, S Fusun, OA Gokhan
WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, Journal Indexed in SCI Expanded, International, 2013, vol 1, pp 51-57
Summary
Aim of the study: This study aimed to evaluate 8-OHdG and hypoxia-inducible factor 1 (HIF-1 alpha) levels in patients with hypoactive thyroid nodules (toxic multinodular goiter, Graves' disease, and Hashimoto's thyroiditis), as these parameters may be related to oxidative stress and the pathogenesis of cancer.