New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential

Articles > Article · 2020

Authors: Hanif Shirinzadeh, Eddy Neuhaus, Elif Ince Erguc, Alev Tascioglu Aliyev, Hande GÜRER ORHAN, Sibel Süzen

Bioorganic Chemistry, Journal Indexed in SCI Expanded, International, WoS, 2020, vol 104, pp 104219-104219

DOI: 10.1016/j.bioorg.2020.104219

Summary

Over the last decade, there has been substantial interest in the use of melatonin (MLT) and MLT-like compounds in the treatment of several diseases. MLT can scavenge different reactive oxygen species and can also stimulate the synthesis of antioxidant enzymes.

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