Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans

Articles > Article ยท 2019

Authors: Deniz M. Ozata, Tianxiong Yu, Haiwei Mou, Ildar Gainetdinov, Cansu Colpan, Katharine Cecchini, Yasin KAYMAZ, Pei-Hsuan Wu, Kaili Fan, Alper Kucukural, Zhiping Weng, Phillip D. Zamore

NATURE ECOLOGY & EVOLUTION, Journal Indexed in SCI Expanded, International, 2019, vol 4, pp 156-168

DOI: 10.1038/s41559-019-1065-1

Summary

By mapping piRNA genes in juvenile and adult human testes, the authors show that although synteny is conserved with other mammals, sequences are diverging rapidly even among modern humans.

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