In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes
Articles > Article · 2001
Authors: Hilmi ORHAN, Gülnaz ŞAHİN
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, Journal Indexed in SCI Expanded, International, 2001, vol 53, pp 133-140
Summary
In vitro effects of widely used nonsteroidal antiinflammatory drugs (NSAIDs) and paracetamol were studied on oxidative stress-related parameters of human red blood cells (RBC). Membrane lipid integrity, activity of erythrocyte antioxidant enzymes; i.e. glutathione S-transferase (GST), selenium dependent-glutathione peroxidase (Se-GPx), and catalase (CAT), and hemolytic/stabilizing action of the drugs on erythrocyte membrane were assessed.