Petek BALLAR KIRMIZIBAYRAK
Eczacılık Fakültesi, Temel Eczacılık Bölümü, Biyokimya Anabilim Dalı
Araştırma alanları: Temel Bilimler, Biyokimya, Sağlık Bilimleri, Yaşam Bilimleri, Moleküler Biyoloji ve Genetik, Tıp, Eczacılık, Temel Eczacılık Bilimleri, Temel Tıp Bilimleri, Sitogenetik
Yayınlar
- Minute-scale electrochemical analysis of cancer cell– anticancer drug interactions at an electrode-confined biointerface (2026)
- Preoperative Prediction of Residual Cancer Burden After Neoadjuvant Chemotherapy in Breast Cancer: A Multimodal Machine Learning Approach and Implications for Clinical Decision Support (2026)
- Sapogenin-based nanoscale assemblies induce immunogenic cell death, remodel the tumor microenvironment, and drive systemic antitumor immunity in melanoma (2026)
- 3-(1H-pyrazole-1-yl/1H-1,2,4-triazole-1-yl)-N-propananilide Derivatives: Design, Synthesis and Neuroprotectivity Potential Against 6-OHDA Induced Neurotoxicity Model (2025)
- Subtype-specific divergent roles of calpain-1 and calpain-2 in basal A triple-negative breast cancer (2025)
- A Candidate Gene for Cerebro-Oculo-Nasal Syndrome: A Zinc-Finger Gene ZNF185 Located at Xq28 (2025)
- Establishment and Validation of an Automated System for the Antifactor IIa Assay: A Case Study of Potency Assessment of a Pharmaceutical Gel Formulation (2024)
- Reprogramming tumor-associated macrophages and inhibiting tumor neovascularization by targeting MANF–HSF1–HSP70-1 pathway: An effective treatment for hepatocellular carcinoma (2024)
- Development of transition metal oxide platforms for aptasensing of PSA in cell cultures (2024)
- MANF serves as a novel hepatocyte factor to promote liver regeneration after 2/3 partial hepatectomy via doubly targeting Wnt/β-catenin signaling (2024)
- 3-(1H-pyrazole-1-yl/1H-1,2,4-triazole-1-yl)-N-propananilide derivatives: Design, Synthesis and Neuroprotectivity Potential Against 6-OHDA Induced Neurotoxicity Model (2024)
- Establishment and Validation of an Automated System for the Antifactor IIa Assay: A Case Study of Potency Assessment of a Pharmaceutical Gel Formulation (2024)
- Anthraquinones and Macrocyclic Lactones from Endophytic Fungus<i> Penicillium</i><i> roseopurpureum</i> and Their Bioactivities (2024)
- Multi-Targeted Effects of Novel Cycloastragenol Derivatives: Enhancing NRF2, Proteostasis, and Telomerase Pathways with p53 Modulation to Delay Replicative Senescence (2024)
- Development of transition metal oxide platforms for aptasensing of PSA in cell cultures (2024)
- Potent telomerase activators from a novel sapogenin via biotransformation utilizing Camarosporium laburnicola, an endophytic fungus (2023)
- Design, synthesis, and biological evaluation of some novel naphthoquinone-glycine/beta-alanine anilide derivatives as noncovalent proteasome inhibitors (2023)
- MANF brakes TLR4 signaling by competitively binding S100A8 with S100A9 to regulate macrophage phenotypes in hepatic fibrosis (2023)
- Differential Expression and Function of SVIP in Breast Cancer Cell Lines and In Silico Analysis of Its Expression and Prognostic Potential in Human Breast Cancer (2023)
- Differential expression and function of SVIP in breast cancer cell lines and in silico analysis of its expression and prognostic potential in human breast cancer (2023)
- Validation of the Anti-factor IIa Assay and Potency Assessment in Pharmaceutical Formulations by Coagulation Analyzer (2023)
- Neuroprotective metabolites via fungal biotransformation of a novel sapogenin, cyclocephagenol (2022)
- Non-apoptotic cell death induction via sapogenin based supramolecular particles (2022)
- Cytotoxic and antimicrobial activities of Ptilostemon chamaepeuce (L.) Less. (2022)
- Short Lecture “Novel neuroprotective metabolites produced via biotransformation of cyclocephagenol by Alternaria eureka 1E1BL1” (2022)
- The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity (2022)
- Induction of Divergent Cell Death Pathways by Urea and Carbohydrazide Derivatives (2022)
- The role of cycloastragenol at the intersection of NRF2/ARE, telomerase, and proteasome activity (2022)
- Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein (2022)
- Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein (2022)
- Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein (2022)
- Nonsteroidal antiinflammatory drugs alter antibiotic susceptibility and expression of virulence-related genes and protein A of Staphylococcus aureus (2021)
- Sapogenin based self-assembly structures activating a non-apoptotic cell death via multiple pathways (2021)
- Evaluation of ATAD2 As a Potential Target in Hepatocellular Carcinoma (2021)
- Undescribed polyether ionophores from Streptomyces cacaoi and their antibacterial and antiproliferative activities (2021)
- Induction of Divergent Cell Death Pathways by Urea and Carbohydrazide Derivatives (2021)
- Neuroprotective activity studies of some phenylacetamide derivatives bearing 1H-pyrazole or 1H-1,2,4-triazole (2021)
- Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors (2021)
- A new underlying mechanism for the neuroprotective effect of bosutinib: Reverting toxicity-induced PARylation in SIN1-mediated neurotoxicity (2021)
- Evaluation of ATAD2 as a Potential Target in Hepatocellular Carcinoma (2021)
- Telomerase activators from 20(27)-octanor-cycloastragenol via biotransformation by the fungal endophytes (2021)
- Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides (2021)
- 20(27)-Octanor-Sikloastragenol’ün Mikrobiyal Transformayonu veElde Edilen Metabolitlerin Telomeraz Aktivasyonu Üzerine Etkileri (2020)
- Divergent Modulation of Proteostasis in Prostate Cancer (2020)
- Divergent Modulation of Proteostasis in Prostate Cancer (2020)
- Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative (2020)
- Aptamer-based electrochemical biosensing strategy toward human non-small cell lung cancer using polyacrylonitrile/polypyrrole nanofibers (2020)
- Telomerase activators derived from Astragalus sapogenins via biotransformation with the recently discovered endophytic fungus Camarosporium laburnicola (2019)
- A new semi-synthetic sapogenol derivative inducing regulated necrosis (2019)
- Synthesis and Bioactivity Studies of Some Naphthoquinone Derivatives (2019)
- Endoplasmic Reticulum-Associated Degradation (ERAD) (2019)
- Endoplasmic Reticulum-Associated Degradation (ERAD) (2019)
- Hypericum perforatum L.: An overview of the anticancer potencies of the specimens collected from different ecological environments (2019)
- Endoplasmic Reticulum-Associated degradation (2019)
- Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells (2019)
- HYPERICUM PERFORATUM L.: AN OVERVIEW OF THE ANTICANCER POTENCIES OF THE SPECIMENS COLLECTED FROM DIFFERENT ECOLOGICAL ENVIRONMENTS (2019)
- Microbial Transformation of Cycloastragenol and Astragenol by Endophytic Fungi Isolated from Astragalus Species (2019)
- Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme (2019)
- Endoplasmic Reticulum-Associated Degradation (ERAD) (2019)
- Endoplasmic Reticulum-Associated Degradation (ERAD) (2019)
- PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis (2019)
- Endoplazmik retikulum-aracılı protein yıkım yolağında görev yapan p97/VCP ve Ufd1-Npl4 adlı proteinlerin NF-κB yolağına etkisinin prostat kanser hücre hattında incelenmesi (2018)
- Polyethers compounds isolated from the marine actinobacterium Streptomyces cacaoi induce apoptosis and inhibit autophagy in HeLa cell line (2018)
- Design, synthesis and evaluation of biological activities of some new carbohydrazide and urea derivatives (2018)
- Regulation of ERAD through Androgen Signaling in Prostate Cancer (2018)
- Endoplazmik retikulum-aracılı protein yıkım yolağında görev yapan p97/vcp ve ufd1-npl4 adlı proteinlerin nf-κb yolağına etkisinin prostat kanser hücre hattında incelenmesi (2018)
- Potansiyel Proteazom İnhibitörü Bir Grup Karbosiklik ve Heterosiklik Bileşiğin Sentez ve Biyoaktivite Çalışmaları (2018)
- Design, synthesis and evaluation of biological activities of some new carbohydrazide and urea derivatives (2018)
- Potential Therapeutic Utility of ERAD Inhibitors in Prostate Cancer (2018)
- Targeting Endoplasmic Reticulum-associated degradation (ERAD) in prostate cancer (2018)
- Regulation of AR Signaling by ER Stress Inducers in Prostate Cancer (2018)
- SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME QUINOXALINE DERIVATIVES (2018)
- Design, synthesis and biological evaluation of nicotinate derivatives for cancer therapy (2018)
- Synthesis and evaluation of pyridinium‐hydrazone derivatives as potential antitumoral agents (2018)
- Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes (2018)
- Dual-Prevention for UV-Induced Skin Damage: Incorporation of Melatonin-Loaded Elastic Niosomes into Octyl Methoxycinnamate Pickering Emulsions (2017)
- Effect of a New Sapogenol Derivative (AG-07) on Cell Death via Necrosis (2017)
- CYTOTOXICITY OF SOME NEW CARBOHYDRAZIDE AND UREADERIVATIVES BEARING PYRIDINE RING (2017)
- Prostat kanserinde yeni bir oyuncu: ERAD (A new player on prostate cancer) (2017)
- Antibiotic and anti-inflammatory drug combinations: alterations on the expression of virulence genes and protein a of Staphylococcus aureus (2017)
- Effect of a New Sapogenol Derivative (AG-07) on Cell Death via Necrosis (2017)
- Yeni PARP İnhibitör Bileşiklerinin Taranması (2017)
- Nazal polip fibroblastlarında TNF-alfa inhibitörlerinin etkisi (2017)
- Anti-inflammatory drugs alter susceptibilityand expression of virulence genes and proteins of staphylococci (2017)
- Niosomes vs Microemulsions: Comparison of the Two Drug Delivery Systems for a Combination Formulation Targeting UV-Induced Skin Damage (2017)
- ERAD: A New Player on Prostate Cancer (2017)
- Androgen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer (2017)
- Androgen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer (2017)
- Development of nanofiber functinionalized aptasensor for electrochemical Detection of cancer cells (2017)
- ERAD inhibisyonunun hormon yokluğu ile kombinasyonunun prostat kanseri hücrelerindeki etkisi (2017)
- The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model (2017)
- A Src/Abl kinase inhibitor, bosutinib, downregulates and inhibits PARP enzyme and sensitizes cells to the DNA damaging agents (2017)
- Androgen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer (2017)
- The effect of R1881 and tunicamycin on the expression levels of SOD1, Catalase and Nrf2 in LNCaP prostate cancer cell line. (2016)
- Androgen-mediated regulation of ER-associated degradation in prostate cancer (2016)
- Batı Anadolu’da yayılış gösteren bazı Hypecoum L. Taksonları üzerinde Kimyasal ve sitotoksik aktivite çalışmaları (2016)
- MANF may attenuate hypoxia/reperfusion-induced renal cell injury (2016)
- Safety Assessment and Antioxidant Activity Screening of Melatonin Loaded Elastic Niosomes Incorporated into Octyl Methoxycinnamate Pickering Emulsion (2016)
- Antiproliferative activity of some tautomeric hydrazones derived from chalcones (2016)
- Electrochemical aptasensor design for label free cytosensing of human non-small cell lung cancer (2016)