Özlem AKGÜL

Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Anabilim Dalı

Research areas: Health Sciences, Pharmacology and Therapeutics, Professional Sciences, Pharmaceutical Chemistry, Natural Sciences, Chemistry, Biochemistry, Alcaloides, Life Sciences, Basic Pharmaceutics Sciences

Publications

• First-in-class nonsteroidal anti-inflammatory drug and carbonic anhydrase inhibitor hybrid compounds as effective antimycobacterial agents (2026)
• EVALUATION OF CARBONIC ANHYDRASE ENZYME INHIBITOR ACTIVITIES OF TAURINE DERIVATIVES CARRYING SECONDARY AMINE GROUP (2025)
• Novel Taurinamide‐Based Compounds as Carbonic Anhydrase Inhibitors (2025)
• Single-crystal X-ray structure, theoretical (Hirshfeld, electronic properties, NBO, NLO, RDG), and molecular docking studies of three phthalimidoethanesulfonamide derivatives (2024)
• SEKONDER AMİN GRUBU TAŞIYAN TAURİN TÜREVLERİNİN KARBONİK ANHİDRAZ ENZİM İNHİBİTÖR AKTİVİTELERİNİN DEĞERLENDİRİLMESİ (2024)
• Exploring the Structure-Activity Relationship of COX Inhibitors with Anticancer Effects: A Comprehensive Review (2024)
• DOĞAL BOYAMA YÖNTEMLERİ İLE RENKLENDİRİLEN GELENEKSEL ÖDEMİŞ İPEKLİ DOKUMALARIN ÖZGÜN TASARIMLARA DÖNÜŞÜMÜ (2024)
• Amino Asit Taşıyan Bir Grup Üre ve Tiyoüre Türevi Bileşiğin Sentezi Ve Antimikrobiyal Aktivitelerinin İncelenmesi (2022)
• İlaç hedefi olarak nükleik asitler (2021)
• Carbonic Anhydrase VII Inhibition Profıle Of A Group Of ThioureaDerivatives (2021)
• Antimicrobial Activity Evaluation of Newly Synthesized N,N-Disubstituted Taurinamidobenzenesulfonamide Derivatives (2021)
• Investigation of Bcl-2 And Bcl-xL Inhibition Profile of A Group of Benzoyltaurinamide Derivative (2021)
• Antimicrobial activity screening of a series of taurine derivatives (2021)
• Inhibition of Carbonic Anhydrase VII Isozyme with a Group of Amide Derivatives (2021)
• Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain (2021)
• Antimicrobial activity of 4-Substituted-N-(2-(N-(4-sulfamoylphenyl)sulfamoyl)ethyl)benzamidederivatives (2021)
• Antimicrobial activity screening of a series of taurine derivatives (2021)
• Antimicrobial Activity Evaluation of Newly Synthesized N,N-Disubstituted Taurinamidobenzenesulfonamide Derivatives (2021)
• Taurultams incorporating arylsulfonamide: First in vitro inhibition studies of α-, β- and γ-class Carbonic Anhydrases from Vibrio cholerae and Burkholderia pseudomallei (2021)
• Carbonic anhydrase inhibition profile of novel aromatic sulfonamide derivatives (2020)
• Inhibition studies of 2-aminoethanesulfonic acid derivatives against some carbonic anhydrase isoforms (2020)
• Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis (2020)
• Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors (2020)
• Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors (2020)
• Design, synthesis, cytotoxic activity, and apoptosis inducing effects of 4- and N-substituted benzoyltaurinamide derivatives (2020)
• Solunum Yolu İlaçları (2019)
• Synthesis and biological evaluation of 2-aminoethanesulfonic acid Incorporating benzenesulfonamide moieties as carbonic anhydrase inhibitors. (2019)
• Single crystal X-ray structural investigations of three new phthalimide derivatives (2019)
• The Synthesis and Carbonic Anhydrase Inhibitory Activity of Some Sulfonamide Derivatives (2019)
• The Synthesis and Carbonic Anhydrase Inhibitory Activity of Some Sulfonamide Derivatives (2019)
• New Carbonic Anhydrase Inhibitors and Non Steroidal Anti-Inflammatory Drugs Hybrids Molecules (NSAIDs-CAIs): a strategy against rheumatoid arthritis (2019)
• Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis (2019)
• Structural determination of biological active N-phenyl-2-phthalimidoethanesulfonamide derivatives (2018)
• Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Management of Rheumatoid Arthritis (2018)
• Structural determination of biological active N-phenyl-2-phthalimidoethanesulfonamide derivatives (2018)
• Bazı taurinamit türevi bileşiklerin sentezi ve antimikrobiyel etkileri (2017)
• Substituent position effect on the crystal structures of N-phenyl-2-phthalimidoethanesulfonamide derivatives (2017)
• Positional isomeric effect on the crystallization of chlorine-substitutedN-phenyl-2-phthalimidoethanesulfonamide derivatives (2015)
• Synthesis and cytotoxic activity of some 2 2 3 dioxo 2 3 dihydro 1H indol 1 yl acetamide derivatives (2013)
• Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives (2013)
• Docking and binding free calculations of inhibitors of SIRT2 (2012)
• The Synthesis and Protease Inhibitory Activity of Some Alkanamide Derivatives (2011)
• The synthesis and proteasome inhibitory activity of some alkanamide derivatives (2010)
• Synthesis and Cytotoxic Activity Evaluations of Some Isatin Derivatives (2010)
• New Electroactive Hybridization Indicators 2‐Phthalimido‐N‐Substitutedphenylethanesulfonamide Derivatives for Biosensor Applications: Ring Substituent Effect on Interaction between Compound and DNA (2010)
• Synthesis and screening of cyclooxgenase inhibitory activitiy of some amide derivatives (2010)
• ChemInform Abstract: Synthesis and Anticonvulsant Activity of Some N‐Phenyl‐2‐phthalimidoethanesulfonamide Derivatives. (2008)
• Electrochemical Biosensor for the Interaction of DNA and ß-Ftalimido-N-feniletansülfonamide (2007)
• Synthesis and Anticonvulsant Activity of Some N‐Phenyl‐2‐phtalimidoethanesulfonamide Derivatives (2007)
• Phototransformation of (+)-Tazettine (2005)

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