Nur SELVİ GÜNEL

Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Anabilim Dalı

Research areas: Health Sciences, Medicine, Natural Sciences, Fundamental Medical Sciences, Internal Medicine Sciences, Medical Biology, Internal Diseases, Life Sciences, Biochemistry, Oncology

Publications

• Intranasal Delivery of Solid Lipid Nanoparticles Loaded with Carmustine and Temozolomide for Glioblastoma Treatment in Mice (2026)
• Optical genome mapping identifies previously undetected causal variants in early-onset developmental epileptic encephalopathies (2026)
• Does physiological sperm selection improve live birth rates in isolated teratozoospermia? A single-center retrospective cohort study (2026)
• PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2025)
• Photobiomodulation therapy enhances surfactant production in premature rat lungs: a non-invasive therapeutic strategy for neonatal respiratory distress syndromes (2025)
• Photobiomodulation therapy enhances surfactant production in premature rat lungs: a non-invasive therapeutic strategy for neonatal respiratory distress syndromes (2025)
• Effect of photobiomodulation therapy on surfactant production increase in human lung epithelial alveolar cells (2025)
• The cytotoxic effects of bio-transformed propolis on healthy and colon cancer cell lines (2025)
• Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells (2025)
• Preparation of dual drug-loaded polymer nanoconjugate to enhance treatment efficacy for ovarian cancer cells (2024)
• PI3K/mTOR Inhibitor VS-5584 Alters Expression of WNT Signaling Genes and Induces Apoptosis in Lung Adenocarcinoma Cells: In Vitro and In Silico Insight (2024)
• Determination of Surfactant Production Increase in Lung Alveolar Cell Lines Using Infrared Phototherapy Method (2024)
• Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery (2024)
• Preparation of dual drug-loaded polymer nanoconjugate to enhance treatment efficacy for ovarian cancer cells (2024)
• KOLON KANSERİNDE PROPOLİS VE 5-FU'NUN KOMBİNASYON UYGULAMASI (2023)
• In Vitro Applications of Drug-carrying Nanoparticle Systems in Cell Culture Studies (2023)
• Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure (2023)
• Investigation of cytotoxic and apoptotic effects of disodium pentaborate decahydrate on ovarian cancer cells and assessment of gene profiling (2022)
• Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death? (2022)
• The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
• OVER KANSERİNDE BOR MİNERALİNİN GÜNCEL TEDAVİ ALANLARI (2022)
• Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death? (2022)
• Functional roles of miR-625-5p and miR-874-3p in the progression of castration resistant prostate cancer (2022)
• The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells (2022)
• Evaluation of IL-10, MCP-1, IFN gamma, and protectin D1 levels in patients with Hashimoto’s thyroiditis (2022)
• Propolisin Kolon Kanseri ve Sağlıklı Hücre Hatlarında INSIG2 Ve PPP2R1A Üzerine Etkisi (2022)
• Propolisin Kolon Kanseri ve Sağlıklı Hücre Hatlarında Sitotoksik ve Voltaj Kapılı Sodyum Kanalı (Nav 1.5) Düzeyine Etkisi (2022)
• The Risk Factors and Clinical Features of Acanthamoeba Keratitis: First Time Detection of Acanthamoeba T5 Genotype from Keratitis Patients in Turkey (2022)
• Investigation of Cytotoxic and Apoptotic Effects of Disodium Pentaborate Decahydrate on Ovarian Cancer Cells and Assessment of Gene Profiling (2022)
• Targeting UPR signaling pathway by dasatinib as a promising therapeutic approach in chronic myeloid leukemia (2022)
• Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells (2022)
• Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells (2022)
• The investigation of T-cell receptor subtypes in ovarian cancer: effects on survival and prognostic factors (2021)
• Brain-targeted, drug-loaded solid lipid nanoparticles against glioblastoma cells in culture (2021)
• Role of inflammatory biomarkers in nephropathy and atherosclerosis in type 2 diabetes mellitus patients with microalbuminuria (2021)
• Ferulik asitin lipopolisakkaridaz ile induklenmiş insan lösemi monositik hücrelerinde sitokin salınımına etkisi (2021)
• Brain-targeted, drug-loaded solid lipid nanoparticles against glioblastoma cells in culture (2021)
• Role of inflammatory biomarkers in nephropathy and atherosclerosis in type 2 diabetes mellitus patients with microalbuminuria (2021)
• Preparation, characterization and in vitro evaluation of cisplatin-bound triblock polymeric micelle solution for ovarian cancer treatment (2021)
• Effect of valproic acid on miRNAs affecting histone deacetylase in a model of anaplastic thyroid cancer (2021)
• The investigation of T-cell receptor subtypes in ovarian cancer: effects on survival and prognostic factors (2020)
• Propolis Prevents Inhibition of Apoptosis by Potassium Bromate in CCD 841 human Colon Cell (2020)
• Effect of Dasatinib on Genes Related to Mitotic Catastrophe Pathway in Chronic Myeloid Leukemia Cells (2020)
• Determination of In vitro Effectiveness of Developed Solid Lipid Nanoparticles For The Treatment of Glioblastoma (2019)
• Cytotoxic Effect of Biologically Transformed Propolis on Hct116 Human Colon Cancer Cells (2019)
• ANTI-ANGIOGENIC EFFECT OF PROPOLIS IS CLOSELY RELATEDTO THE SOLVATION METHOD AND BIOTRANSFORMATIONPROCESS (2019)
• Induction of APAF-1 and TRAIL by bilberry tea in HCT-116 colon cancercell line (2019)
• Lösemi Hücrelerinde STAT3’xxün Hedeflenmesi Metabolik Potansiyel Değişimi ile Glikolizi Modüle Eder (2019)
• Dabrafenib ve Epigallokatesin-3-gallatUygulanmis Anaplatik Tiroid KanserModelinde Epigenetik Duzenleyici GenlerinProfillenmesi (2019)
• Akciğer adenokarsinomlu olgularda birinci basamak tedavi sonrası onkogendeğişimlerinin periferik kan serbest DNA (cfDNA) örneklerinden araştırılması (2019)
• Cytotoxic Effect of Biologically Transformed Propolis on Hct116 Human Colon Cancer Cells (2019)
• Anti-Angiogenic Effect of Propolis is Closely Related to the Solvation Method and Biotransformation Process (2019)
• Effects of Rituximab on JAK-STAT and NF-kappa B signaling pathways in acute lymphoblastic leukemia and chronic lymphocytic leukemia (2019)
• Induction of PAF-1 and TRAIL by Bilberry Tea in HCT-116 Colon Cancer Cell Line (2019)
• Allergenic Phenolic Content and Antioxidant Capacity of Biotransformed Propolis by Lactobacillus plantarum (2018)
• KCF2 ve Temozolomide etken maddelerinin U87-MG Glioma hücre modeli üzerindeki sitotoksik ve apoptotik etkileri (2018)
• Farklı Çözgenlerde Hazırlanmış Propolisin Sağlıklı ve Kanser Hücre Hatları Üzerindeki Sitotoksik Etkisi (2018)
• Allergenic Phenolic Content and Antioxidant Capacity of Biotransformed Propolis by Lactobacillus plantarum (2018)
• Hydroxycinnamic Acids in Wild Blueberry andEffects of Hydroxycinnamic Acids on Apoptosis (2018)
• Synergistic effect of ponatinib and epigallocatechin-3-gallate induces apoptosis in chronic myeloid leukemia cells through altering expressions of cell cycle regulatory genes. (2018)
• Farklı Çözgenlerde Hazırlanmış Propolisin Sağlıklı ve Kanser Hücre Hatları Üzerindeki Sitotoksik Etkisi (2018)
• Baş Boyun Kanser Kök Hücresinde ICRT-3’ün Apoptotik Etkisi (2018)
• The Apoptotic Effect of Dabrafenib and Epigallocatechin-3-gallate Combination on Anaplastic Thyroid Cancer Cells (2018)
• Cell culture techniques (2018)
• PHİLADELPHİA POZİTİF KML OLGULARINDA JAK2 V617FMUTASYONUNUN PREVALANSI (2018)
• Hydroxycinnamic Acids in Wild Blueberry and Effects of Hydroxycinnamic Acids on Apoptosis Induction in Cancer Cell Culture (2018)
• Küçük Hücreli Dışı Akciğer Kanseri Hastalarında Onkogen Mutasyonlarının Araştırılması. (2018)
• Bendamustin ile indüklenen HL60 hücre serisinde apoptozun ve hücre döngüsünde görevli genlerin ekspresyon değişimlerinin belirlenmesi (2018)
• Determination Frequency of XRCC1 (rs25487) Gene Polymorphism in Turkish Ovarian Cancer Patients. (2017)
• Bölüm 2: Tıbbi Genetikte Kullanılan Yöntemler (2017)
• Determination of cytotoxicity in triblock polymer bound-cisplatin on ovarian cancer cell (2017)
• Biologically transformed propolis exhibits cytotoxic effect on A375 malignant melanoma cells in vitro (2017)
• Targeting Upr mechanism by dasatinib as a promising therapeutic approach in chronic myeloid leukemia. (2017)
• Türkiye’de Naegleria fowleri’nin etken olduğu ilk meningoansefalitolgusu (2017)
• Biologically transformed propolis exhibits cytotoxic effects on A375 Malignant Melanoma Cells in Vitro (2017)
• Investigation of the prevalence of Acanthamoeba keratitis in Turkey (2017)
• Determination of EGFR, KRAS, BRAF, PIK3CA, HER2 and NRAS Gene Mutations in Parafin Block Sections from Patients Diagnosed with Non- Small Cell Lung Cancer (2017)
• Yumuşak kontakt lens kullanan hastada Acanthamoeba’nın moleküler ve kültür yöntemleri ile tanısı (2017)
• Determination of AURK A and AURK B expression levels in dasatinibtreated K562 cells (2017)
• Determination Frequency of XRCC1 (rs25487) Gene Polymorphism in Turkish Ovarian Cancer Patients (2017)
• Western Blot Yötemi (2017)
• Telomerase inhibitor BIBR1532 effects on epigenetic mechanisms in U87MG brain tumors. (2017)
• Dasatinib ile muamale edilen K562 hücre serisinde, dasatinibin PP2A katalitik ve regulatuvar alt birimlerinde, enzim aktivitesine ve protein ekspresyonu üzerine etkisinin değerlendirilmesi (2017)
• Biologically transformed Propolis Exhibits Cytotoxic Effect on A375 Malignant Melanoma Cells In Vitro (2017)
• Extramedullary Relapse in a CML Patient after Allogeneic Stem Cell Transplantation (2017)
• Lösemilerde t(922) BCR-ABL TranslokasyonununReal-Time RT-PCR ile 10 Yıllık SonuçlarınınRetrospektif Değerlendirilmesi (2016)
• Determination of apoptosis and changes on cell cycle genes expressions in HL60 cell line induced with bendamustine (2016)
• Temozolomid ve vismodegib kombinasyonu beyin tümörü hücrelerinde apoptozu indükler. (2016)
• Akut Lenfoblastik Lösemi Hastalarında T(12;21) TEL-AML1 Translokasyonunun Gerçek Zamanlı Qrt-PZR İle 5 Yıllık Sonuçlarının Değerlendirilmesi (2016)
• Lösemilerde t(9;22) BCR-ABL Translokasyonunun Real-Time RT-PCR ile 10 Yıllık Sonuçlarının Retrospektif Degerlendirilmesi (2016)
• Promising Theurapatic target of PP2A and effect of Apoptosis on KML (2016)
• Akut lenfoblastik lösemi hastalarında t 12 21 TEL AML1 translokasyonunun gerçek zamanlı qRT PZR ile 5 yıllık sonuçlarının değerlendirilmesi (2016)
• Beyin Kanserinde Kök Hücreleri Hedefleyen Yeni Terapötik Ajan: Vismodegib (2016)
• Lösemi Hücrelerinde genom geneli mRNA ve microRNA ekpresyon profillerinin analizi STAT5A nın susturulmasıyla kemoterapötik imatinib yanıtının geri kazanılmasında mir 2278 in tümör supresör olduğuna işaret eder (2016)
• The Variation of serum Soluble CD40Ligand sCD40L Levels During Controlled Ovarian Stimulation Preliminary Results (2016)
• The evaluation of the effects of dasatinib on protein expression and the enzymatic activity of PP2A catalytic and regulatory subunits that are dasatinib treated K652 cell line (2016)
• Genomik Uygulama Sonuçlarının Değerlendirilmesi (2016)
• BCR ABL Translokasyonunun Real Time RT PCR ile 10 Yıllık Sonuçlarının Retrospektif Değerlendirilmesi (2016)
• Prostat kanseri hücrelerinde MAP kinaz gen ekspresyonlarını yukarı doğru regüle eden disodyum pentaborat dekahidrat (2016)
• Disodium Pentaborate Decahydrate up regulates expressions of MAPkinase genes in human prostate cancer cells (2016)

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