Mustafa KOTMAKÇI
Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü, Farmasötik Biyoteknoloji Anabilim Dalı
Research areas: Health Sciences, Pharmacology and Therapeutics, Natural Sciences, Pharmaceutical Biotechnology, Pharmaceutics Technology, Life Sciences, Basic Pharmaceutics Sciences, Medicine, Fundamental Medical Sciences, Medical Biology
Publications
- Cationic Lipid Nanoparticles for miR-34A Delivery to Lung Cancer Cells: Comparative Evaluation of Plasmid DNA and Oligonucleotide Formulations (2026)
- Development of an extracellular vesicle-based shRNA delivery system to overcome cisplatin resistance in non-small cell lung cancer by targeting STAT3 (2026)
- Comparison of nose-to-brain and systemic delivery of STING agonist-loaded liposomes for glioblastoma treatment (2025)
- Comparison of nose-to-brain and systemic delivery of STING agonist-loaded liposomes for glioblastoma treatment (2025)
- Plasmid DNA Delivery to Cancer Cells with Poly(L-lysine)-Based Copolymers Bearing Thermally Sensitive Segments: Balancing Polyplex Tightness, Transfection Efficiency, and Biocompatibility (2025)
- INVESTIGATION OF LIPID NANOPARTICLE:PDNA COMPLEX INTERACTIONS WITH BIOLOGICAL MATERIAL (2024)
- P12-23 Comparative mitochondrial changes in Paracetamol-induced kidney and liver toxicity in mice (2024)
- Preparation and characterization of STING agonists-delivering LNP systems for cancer treatment (2023)
- Enhanced cytokine stimulation in in vitro and in vivo glioblastoma models: Lipid nanoparticles for stimulator of interferon genes agonists delivery (2023)
- D-α-tocopherol polyethylene glycol (1000) succinatecontaining microemulsion enhances the anticancer effect of cisplatin in human lung epidermoid carcinoma cells (2023)
- ORTOTOPİK-SİNGENİK FARE GLİOBLASTOMA MODELİNDE İNTRANAZAL NANOPARTİKÜL İLAÇ UYGULAMASI (2022)
- Rekombinant Peptid-Protein İlaçların Stabilitesi ve Formülasyon Stratejileri (2022)
- Biyoteknolojik İlaç Üretiminin Esasları (2022)
- Terapötik Monoklonal Antikorlar: Yapısal Tasarım, Üretim ve Terapötik Uygulama (2022)
- Oligonükleotid İlaçlar ve Gen Taşıyıcı Sistemler (2022)
- Biyobenzer İlaçlar (2022)
- Additional file 1 of Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids (2021)
- Additional file 1 of Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids (2021)
- SIRT1 siRNA-loaded lipid nanoparticles enhanced doxorubicin-induced cell death in prostate cancer cell lines (2021)
- Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids (2021)
- Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids (2020)
- A promising approach to develop nanostructured lipid carriers from solid lipid nanoparticles: preparation, characterization, cytotoxicity and nucleic acid binding ability (2020)
- Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids (2020)
- Development of SIRT1 siRNA-carrying liposomes for treatment of prostate cancer (2020)
- Evaluation of the effect of solid and cationic lipids on siRNA delivery systems (2020)
- Enhanced Cellular Uptake and Gene Silencing Activity of Survivin-siRNA via Ultrasound-Mediated Nanobubbles in Lung Cancer Cells (2020)
- Ultrasound Sensitive Nanobubbles Containing Paclitaxel, YM155 and siRNA as Gene Carriers for the Therapy of Lung Cancer (2019)
- Antibiofilm activities of phytosphingosine and phytosphingosine hydrochloride against bacteria and fungi (2019)
- Evaluation of the cationic solid lipid nanoparticlescarrying siRNA against EphA2 receptor as non-viraldelivery systems (2019)
- Development and characterization of nanobubbles containing paclitaxel and survivin inhibitor YM155 against lung cancer (2019)
- Nutlin3a-Loaded Nanoparticles Show Enhanced Apoptotic Activity on Prostate Cancer Cells (2019)
- Majistral Ürünler (2018)
- Aşılar (2018)
- Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative (2018)
- In vitro genotoxicity and cytotoxcity of miceller formulation of sugar bounded commercial anticancer agent (2018)
- Solid Lipid Nanoparticle (SLN) Complexes with Plasmid or Oligonucleotide for miR-34a Delivery (2018)
- Akciğer Kanseri Tedavisinde Gen Taşıyıcı Nanobaloncuklar (2018)
- Solid Lipid Nanoparticle complexes with plasmid or oligonucleotide for miR-34a delivery (2018)
- Nanobubbles as Gene Carriers for the Therapy of Lung Cancer (2018)
- DEVELOPMENT AND CHARACTERIZATION OF ULTRASOUND SENSITIVE PACLITAXEL, SURVIVIN siRNA AND YM155 LOADED NANOBUBBLES AGAINST LUNG CANCER (2018)
- Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative (2018)
- Preparation and characterization of non-viral gene delivery systems with pEGFP-C1 Plasmid DNA (2018)
- Antimicrobial Activity of Phytosphingosine Nanoemulsions against Bacteria and Yeasts (2018)
- Exosome Isolation: Is There an Optimal Method with Regard to Diagnosis or Treatment? (2017)
- From the Immune Response to the Genome Design CRISPR-Cas9 System: Review (2017)
- Exosome Isolation: Is There an Optimal Method with Regard to Diagnosis or Treatment? (2017)
- Development and Evaluation of Monoclonal Antibody Fragment-attached Solid Lipid Nanoparticles for Targeted Delivery to Cancer Cells (2017)
- Development of positive-charged solid lipid nanoparticles as siRNA delivery systems for treatment of glioblastoma (2017)
- Ekstraselüler veziküller- tanıda ve ilaç taşınmasında yeni oyuncular (Extracellular vesicles - new players in the diagnosis and drug delivery) (2017)
- EVs in cisplatin resistance and transmitting resistance in Calu1 non-small cell lung cancer cells (2017)
- An optimized procedure to obtain extracellular vesicles for delivering STAT3-suppressing short RNA molecules to NSCLC cells (2017)
- Preparation and characterization of lipid nanoparticle/pDNA complexes for STAT3 downregulation and overcoming chemotherapy resistance in lung cancer cells (2017)
- From the Immune Response to the Genome Design; CRISPR-Cas9 System: Review (2017)
- Formulation, characterisation and Salmonella/Microsome mutagenicity assay of a novel 5-fluorouracil derivative (2016)
- Improved Method for Solid Lipid Nanoparticle Preparation Based on Hot Microemulsions: Preparation, Characterization, Cytotoxicity, and Hemocompatibility Evaluation (2016)
- Nanoencapsulated chitosan nanoparticles in emulsion-based oral delivery system: In vitro and in vivo evaluation of insulin loaded formulation (2016)
- In vivo evaluation of rh insulin loaded microemulsion as oral delivery system (2015)
- EFFECT OF VITAMIN-E DERIVATIVES-CONTAINING MICROEMULSION ON THE CHEMOTHERAPEUTIC RESPONSE IN LUNG CANCER CELL LINES (2015)
- Characterization and Antimicrobial Activity of NovelHazelnut Oil Microemulsion Loaded with Mitomycin C (2015)
- Solid lipid nanoparticles for gene silencing in chemoresistant cancer cells (2015)
- Extracellular Vesicles as Natural Nanosized Delivery Systems for Small-Molecule Drugs and Genetic Material: Steps towards the Future Nanomedicines (2015)
- Determining antimicrobial potential of novel mitomycin C-loaded microemulsion systems (2014)
- Preparation of dna delivery systems for dermal gene delivery (2014)
- Size variation of solid lipid nanoparticles prepared from various points of hot microemulsion phase diagrams (2014)
- Determination of In Vivo Behavior of Mitomycin C-Loaded O/W Soybean Oil Microemulsion and Mitomycin C Solution Via Gamma Camera Imaging (2013)
- Cytotoxicity Study on Cationic Solid Lipid Nanoparticles as DNA Delivery System (2012)
- Solid Lipid Nanoparticles from Hot Microemulsions: a Method to Screen Hot Pseudoternary Phase Diagram, and Size Quality of Selected Formulations (2012)
- Preparation of microemulsion systems for carbamazepine delivery (2012)
- Cytotoxicity of a Novel Oil/Water Microemulsion System Loaded with Mitomycin-C in In Vitro Lung Cancer Models (2012)
- Development of novel cationic solid lipid nanoparticles as gene delivery system: Characterization and transfection ability (2011)
- Determining in vitro anticancer activity of mitomycin C loaded microemulsion (2011)
- Development of novel precirol based cationic solid lipid nanoparticles by microemulsion dilution method as DNA delivery system (2011)
- In vitro Study of Hemolytic Potential of Microemulsion Formulation for Intravenous Delivery (2010)
- IN VITRO RELEASE AND IN VIVO GAMMA CAMERA IMAGING OF MITOMYCIN C- LOADED SOYBEAN OIL MICROEMULSION (2010)
- IN VITRO RELEASE STUDY OF MITOMYCIN C LOADED O/W MICROEMULSION FORMULATION (2009)
- Mitomycin-C Loaded O/W Soybean Oil Microemulsion for Parenteral Delivery (2009)