Güneş ÇOBAN
Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Anabilim Dalı
Research areas: Health Sciences, Pharmacology and Therapeutics, Professional Sciences, Natural Sciences, Pharmaceutical Chemistry, Chemistry, Basic Pharmaceutics Sciences, Life Sciences, Biochemistry, Pharmacognosy
Publications
- Targeted and Untargeted Metabolomics and Pharmacological Potential of Endemic Stachys sparsipilosa R. Bhattacharjee & Hub.-Mor. (2026)
- Helianthemum oelandicum subsp. incanum and Fumana thymifolia: Characterization of LC-ESI-QTOF-MS profiles and their biological activities based on plant parts and extraction solvents. (2025)
- Novel Triazolopyrimidinone Compounds as Inhibitors of Adipocyte Fatty Acid–Binding Protein (FABP4) (2025)
- ISATIN/PHTHALIMIDE-MANNICH BASES AS POTENTIAL α-GLUCOSIDASE INHIBITORS: DESIGN, SYNTHESIS and BIOACTIVITY STUDIES (2025)
- Variability of Isoquinoline Alkaloid Profiles and Anticholinesterase Activities with Binding-Mode Predictions of <i>Glaucium flavum</i> Population (2024)
- Design, synthesis, biological evaluation, and molecular modeling studies of some quinazolin-4(3H)-one-benzenesulfonamide hybrids as potential alpha-glucosidase inhibitors (2024)
- Variability of Isoquinoline Alkaloid Profiles and Anticholinesterase Activities with Binding-Mode Predictions of Glaucium flavum Population (2024)
- Discovery of selective TYK2 inhibitors: Design, synthesis, in vitro and in silico studies of promising hits with triazolopyrimidinone scaffold (2024)
- Discovery of selective TYK2 inhibitors: Design, synthesis, in vitro and in silico studies of promising hits with triazolopyrimidinone scaffold (2024)
- TYK2 ENZİMİNİN TAHMİNİ ALLOSTERİK İNHİBİTÖRÜNÜN SANAL YÜKSEK VERİMLİ TARAMA VE MOLEKÜLER DİNAMİK SİMÜLASYONLARI İLE BELİRLENMESİ (2023)
- Detecting Binding Mode of Belumosudil Inside ROCK2 by Molecular Docking Study and Molecular Dynamics Simulations (2023)
- Studies On Some 4-Phthalimidobenzensulfonamide Derivatives As Potential MTDL For The Treatment Of AD And T2DM. (2023)
- Structure-based virtual screening and molecular dynamics simulations for detecting novel candidates for allosteric inhibition of EGFRT790M (2023)
- Metabolomics profiling, biological activities, and molecular docking studies of elephant garlic (Allium ampeloprasum L.) (2022)
- Adrenerjik Sinir Sistemi Üzerine Etkili İlaçlar (2021)
- İlaç hedefi olarak nükleik asitler (2021)
- Dexpanthenol and ascorbic acid ameliorate colistin-induced nephrotoxicity in rats. (2021)
- Design, Synthesis and Bioactivity Studies of Novel Triazolopyrimidinone Compounds (2021)
- Structure-based virtual screening and molecular dynamics simulations for detecting novel candidates as FGFR1 inhibitors (2021)
- Design, synthesis, and in vitro biological evaluation of novel thiazolopyrimidine derivatives as antileishmanial compounds (2020)
- A comprehensive study on narcissus tazetta subsp. tazetta L.: Chemo-pro filing, isolation, anticholinesterase activity and molecular docking of amaryllidaceae alkaloids (2020)
- Synthesis, biological evaluations and molecular modelling studies of novel indolin-2-ones designing as FGFR inhibitors (2019)
- . Effect of the triazolopyrimidine compound on endogenous H2S levels in lung tissue homogenates: A scaffold hopping application on resveratrol derıvatıves. (2018)
- NEW HETEROCYCLIC COMPOUNDS WITH ANTILEISHMANIAL ACTIVITY: DESIGN, SYNTHESIS, BIOACTIVITY AND MOLECULAR MODELLING STUDIES (2018)
- REVERSAL ANTIBIOTIC RESISTANCE with MTDL STRATEGIES: NMP (NAPHTHYLMETHYLPIPERAZINE) HYBRIDS (2018)
- Multifunctional cholinesterase inhibitors for Alzheimer's disease: Synthesis, biological evaluations, and docking studies of o/p‐propoxyphenylsubstituted‐1H‐benzimidazole derivatives (2018)
- EFFECT of THE TRIAZOLOPYRIMIDINE COMPOUND on ENDOGENOUS H2S LEVELS in LUNG TISSUE HOMOGENATES:A SCAFFOLD HOPPING APPLICATION on RESVERATROL DERIVATIVES (2018)
- SYNTHESIS AND BIOLOGICAL EVALUATION OF ORTHO-PROPOXYPHENYL SUBSTITUTED 1H-BENZIMIDAZOLE DERIVATIVES AS BUCHE AGENTS (2017)
- Mannich‐Benzimidazole Derivatives as Antioxidant and Anticholinesterase Inhibitors: Synthesis, Biological Evaluations, and Molecular Docking Study (2017)
- Synthesis and Biological Evaluatıon of Ortho-Propoxyphenyl Substıtuted 1H-Benzimidazole Derivatives as Buche Agents (2017)
- Leader Compound Optimization Studies on 1H-Benzimidazole Derivatives for Alzheimer Disease (2017)
- Mannich-Benzimidazole Derivatives as Antioxidant and Anticholinesterase Inhibitors: Synthesis, Biological Evaluations, and Molecular Docking Study (2017)
- Alkaloid profiling, anticholinesterase activity and molecular modeling study of Galanthus elwesii (2017)
- 1H-benzimidazole derivatives as butyrylcholinesterase inhibitors: synthesis and molecular modeling studies (2016)
- Synthesis, biological activity screening and molecular modeling study of acylaminoacetamide derivatives (2015)
- Design Synthesis Biological Evaluation and MolecularModeling of 1H Benzimidazole Derivatives asAcetyl Butyrylcholinesterase Inhibitors (2014)
- Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells (2009)
- Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells (2008)
- Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays (2008)
- SYNTHESIS AND KINETIC EVALUATION OF 1H BENZIMIDAZOLE DERIVATIVES AS MAMMALIAN DNA TOPOISOMERASE I INHIBITORS (2007)
- Synthesis And 1H NMR Spectrum of Some 1H Benzimidazole Derivatives (2007)
- Synthesis And Evaluation of Some 1H Benzimidazole Derivatives Topoisomerase I Inhibitors (2007)
- Effects of Chain Length And The Alkyl Groups On The Inhibitory Activity of Bisbenzimidazoles In DNA Topoisomerase I Supercoil Relaxation Activity (2007)