Ege ARZUK
Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Toksikoloji Anabilim Dalı
Research areas: Health Sciences, Pharmacology and Therapeutics, Professional Sciences, Natural Sciences, Life Sciences, Pharmaceutical Toxicology, Basic Pharmaceutics Sciences, Neurobiology, Neurosystems, Biochemistry
Publications
- CHARACTERIZATION OF LEUCO METHYLTHIONINIUM BIS-CONTAINING NANOPARTICLES FOR ALZHEIMER’S DIAGNOSIS (2026)
- Synthesis and biological evaluation of benzyloxymethyl-substituted imidazo[1,2-a]pyridines as apoptosis-inducing anticancer agents through modulation of BCL-2/Bax signaling and caspase-3 activation (2026)
- Evaluation of an Integrated In Silico-In Vitro Pipeline for Predicting Mitochondrial Complex I-Mediated Neurotoxicity of Chlorpyrifos (2026)
- Synthesis, Antiproliferative Activity, and Pre-Admet Studies of P-Aminophenyl Substituted Benzoxazole Derivatives Designed Based on Phortress (2025)
- Synthesis of New Pyrazolo[1,5‐ a ]Pyrazin‐4(5 H )‐One Derivatives and Effects on PI3K Protein Levels in A549 Lung Adenocarcinoma Cell Line (2025)
- Synthesis, biological evaluation and molecular modeling studies of quinazolin-4(3H)-one and benzenesulfonamide hybrids as potential anticancer agents (2025)
- Exploring the role of quercetin on doxorubicin and lapatinib-mediated cellular and mitochondrial responses using in vitro and in silico studies (2025)
- Synthesis of thiazole-integrated pyrrolotriazinones: evaluations of cytotoxicity and effects on PI3K levels in cancer cells (2025)
- Investigation of the role of NLRP3 inflammasome activation in new-generation BCR-ABL1 tyrosine kinase inhibitors-induced hepatotoxicity (2024)
- Matairesinol induced antiproliferative effects via mitochondrial dysfunction in HepG2 cells. (2024)
- Genistein and daidzein induce ferroptosis in MDA-MB-231 cells (2024)
- In vitro assessment of the role of endoplasmic reticulum stress in sunitinib-induced liver and kidney toxicity (2024)
- Correction: Celecoxib inhibits NLRP1 inflammasome pathway in MDA-MB-231 Cells (2024)
- Novel Pyrazole Derivatives Bearing Carbonitrile and Substituted Thiazole Moiety for Selective COX-2 Inhibition (2024)
- Mitochondrial Impact of Organophosphate Pesticide-Induced Cardiotoxicity: An In Silico and In Vitro Study (2024)
- Effect of n-Hexane Extract from Tanacetum argenteum (Lam.) Willd. subsp. argenteum on the Secretion of Proinflammatory Cytokines in THP-1 Cell Line (2024)
- Celecoxib inhibits NLRP1 inflammasome pathway in MDA-MB-231 Cells (2024)
- P12-13 Role of endoplasmic reticulum stress in sunitinib-induced hepatotoxicity (2024)
- Mitochondrial toxicity of selected natural compounds: in vitro assessment and in silico molecular docking and dynamics simulation (2024)
- Pharmacological and Toxicological Effects of Cannabinoids on Gastrointestinal Tract And System (2023)
- Pharmacological and Toxicological Effects of Cannabinoids on Stroke (2023)
- The Effects of Cannabinoids on Cardiovascular System (2023)
- In silico and In vitro Evaluation of Oxypeucedanin-Induced Anticancer Activity and Mitotoxicity (2023)
- ISOIMPERATORIN-MEDIATED ANTICANCER ACTIVITY: ROLE OF MITOCHONDRIAL DYSFUNCTION IN HEPG2 CELLS (2023)
- Design, synthesis, and antiproliferative activities of novel thiazolyl-pyrazole hybrid derivatives (2023)
- Role of Oxidative Stress and Reactive Metabolites in Cytotoxicity & Mitotoxicity of Clozapine, Diclofenac and Nifedipine in CHO-K1 Cells In Vitro (2023)
- INVESTIGATION OF CYTOTOXIC AND APOPTOTIC EFFECTS OF PRANGOS HEYNIAE H. DUMAN & M. F. WATSON EXTRACTS ON HEPG2 CELLS (2023)
- Matairesinol induced antiproliferative effects via mitochondrial dysfunction in HepG2 cells (2023)
- In silico and in vitro evaluation of oxypeucedanin-induced anticancer activity: Mitotoxicity? (2023)
- Radiolabeled Trastuzumab Solid Lipid Nanoparticles for Breast Cancer Cell: in Vitro and in Vivo Studies (2022)
- Mitochondrial versus microsomal bioactivation of paracetamol by human liver and kidney tissues (2022)
- REPURPOSING DRUGS FOR CANCER THERAPY (2022)
- Toxicology of Herbal Medicines (2021)
- Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity (2021)
- INVOLVEMENT OF REACTIVE METABOLITES IN CYTOTOXIC EFFECTS OF VARIOUS FREQUENTLY USED DRUGS IN VITRO (2018)
- Stability of mitochondrial intactness for further toxicological studies (2018)
- Investigation of Mitochondrial Respiration Dysfunction Caused by Some Drugs (2018)
- Inter-individual and inter-organ variability in the bioactivation of paracetamol by human liver and kidney tissues (2018)
- Measurement of 8-oxo-7,8-dihydro-2′-deoxyguanosine in urine by an improved ELISA (2017)
- Measurement of 8-oxo-7,8-dihydro-2-deoxyguanosine in urine by an improved ELISA (2017)
- Urinary 8-oxo-7,8-dihydro-2 '-deoxyguanosine analysis by an improved ELISA: An inter-laboratory comparison study (2016)
- Biotransformation of clozapine by microsomaland mitochondrial fractions of mouse liver andheart Organ specific bioactivation as a possiblecause of cardiotoxicity (2016)
- Contribution of reactive metabolites to cytotoxicity of various drugs in vitro: The role of CYP enzymes and metal contamination (2016)
- Contribution of reactive metabolites to cytotoxicity of various drugs in vitro The role of CYP enzymes and metal contamination (2016)
- Biotransformation of clozapine by microsomal and mitochondrial fractions of animal liver and heart: organ-specific bioactivation as a possible cause of cardiotoxicity (2016)
- LC TANDEM MS BASED ASSESSMENT OF ACETAMINOPHEN IN HUMAN LIVER AND KIDNEY NAPQI FORMATION AND CYP ACTIVITIES (2015)
- ROSIGLITAZONE BIOTRANSFORMATION IN VITRO ENZYMES FROM DIFFERENT SOURCES AND THE EFFECT OF VARIOUS GLUTATHIONE S TRANSFERASES IN ELECTROPHILIC INTERMEDIATE CONJUGATION (2015)
- Rosiglitazone biotransformation in vitro: Enzyme from different sources and rat organs, and the effect of various glutathione S-transferases in electrophilic intermediate conjugation. (2015)
- INTERINDIVIDUAL VARIABILITY IN GENERATING ACETAMINOPHEN REACTIVE METABOLITE NAPQI BY VARIOUS HUMAN LIVER AND KIDNEY MICROSOMES (2013)