Ayşe Hande TARİKOĞULLARI DOĞAN

Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Anabilim Dalı

Research areas: Health Sciences, Natural Sciences, Pharmacology and Therapeutics, Biochemistry, Chemistry, Basic Pharmaceutics Sciences, Life Sciences, Professional Sciences, Pharmaceutical Chemistry, Alcaloides

Publications

• Design, Synthesis, and In Silico Analyses of Nitroimidazole Derivatives Targeting Cholinesterases (2025)
• Design, synthesis, and biological evaluation of some novel naphthoquinone-glycine/beta-alanine anilide derivatives as noncovalent proteasome inhibitors (2023)
• N‐Substituted piperidine‐3‐carbohydrazide‐hydrazones against Alzheimer's disease: Synthesis and evaluation of cholinesterase, beta‐amyloid inhibitory activity, and antioxidant capacity (2023)
• Exploring enzyme inhibition profiles of novel halogenated chalcone derivatives on some metabolic enzymes: Synthesis, characterization and molecular modeling studies (2022)
• Design, synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-β aggregation inhibition studies of substituted 4,4ʹ-diimine/4,4ʹ-diazobiphenyl derivatives (2022)
• N‐Substituted piperidine‐3‐carbohydrazide‐hydrazones against Alzheimers disease: Synthesis and evaluation of cholinesterase, beta‐amyloid inhibitory activity, and antioxidant capacity (2022)
• İlaç hedefi olarak nükleik asitler (2021)
• İlacın Piyasaya Sürülmesi (2021)
• Neuroprotective activity studies of some phenylacetamide derivatives bearing 1H-pyrazole or 1H-1,2,4-triazole (2021)
• Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors (2021)
• Cholinergic Agents (2019)
• Antidepresanlar (2019)
• Solunum Yolu İlaçları (2019)
• Neuroprotective Evaluation of Some Phenylacetamide Derivatives Bearing 1,2,4-triazole with Metal Binding Property (2018)
• Acetylcholinesterase inhibitory activity and docking studies of some substituted N-phenylacetamide derivatives (2018)
• Multifunctional cholinesterase inhibitors for Alzheimer's disease: Synthesis, biological evaluations, and docking studies of o/p‐propoxyphenylsubstituted‐1H‐benzimidazole derivatives (2018)
• SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME QUINOXALINE DERIVATIVES (2018)
• Synthesis, biological evaluation, and docking studies of some 5-chloro-2(3H)-benzoxazolone Mannich bases derivatives as cholinesterase inhibitors (2018)
• Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones (2018)
• SYNTHESIS AND BIOLOGICAL EVALUATION OF ORTHO-PROPOXYPHENYL SUBSTITUTED 1H-BENZIMIDAZOLE DERIVATIVES AS BUCHE AGENTS (2017)
• Synthesis and Biological Evaluation of Some Piperidine Hydrazide-Hydrazone Derivatives as AChE/BuChE Inhibitors (2017)
• Synthesis and Biological Evaluatıon of Ortho-Propoxyphenyl Substıtuted 1H-Benzimidazole Derivatives as Buche Agents (2017)
• Leader Compound Optimization Studies on 1H-Benzimidazole Derivatives for Alzheimer Disease (2017)
• 1H benzimidazole derivatives as butyrylcholinesterase inhibitors synthesis and molecular modeling studies (2016)
• Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors (2016)
• Synthesis, Biological Evaluation and Molecular Docking Study of Hydrazone-Containing Pyridinium Salts as Cholinesterase Inhibitors (2016)
• Synthesis and cholinesterase inhibitory activity of some phenylacetamide derivatives bearing 1H-pyrazole and 1H-1,2,4-triazole (2015)
• Design Synthesis Biological Evaluation and MolecularModeling of 1H Benzimidazole Derivatives asAcetyl Butyrylcholinesterase Inhibitors (2014)
• Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives (2013)
• Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors (2013)
• Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide derivatives (2013)
• Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives (2013)
• Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors (2013)
• Docking and binding free calculations of inhibitors of SIRT2 (2012)
• Synthesis and anticonvulsant activity of some alkanamide derivatives (2011)
• The synthesis and proteasome inhibitory activity of some alkanamide derivatives (2010)
• Synthesis and Cytotoxic Activity Evaluations of Some Isatin Derivatives (2010)
• Synthesis and anticonvulsant activity of some alkanamide derivatives (2010)
• N-(Sübstitüefenil) asetamit ve propiyonamit türevi bazı bileşiklerin antikonvülzan aktivitelerinin değerlendirilmesi (2007)
• Synthesis and characterization of some 2(3H)-benzoxazolone derivatives (2001)
• The synthesis and structural characterization of some 2 3H benzoxazolone derivatives (2001)

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