Epidemiology of Sexually Transmitted Infections in HIV (+) Persons
Project no. 4 · Status: Kapanmış · 2015
Summary
OBJECTIVE: The aim of this study was to investigate the effects of sexually transmitted disease agents such as N. gonorrhoeae, C. trachomatis, T. vaginalis, M. genitalium, M. hominis, U. urealyticum, U. parvum, HSV 1 and HSV 2, 19 high risk genotype HPV and 9 low risk genotype and determining the frequency of the agents in HIV-positive individuals. MATERIALS AND METHODS: Between September 2015 and April 2016, vaginal and urethral swab samples were collected from 90 HIV positive patients (14 female, 15.6% male, 84.4%). The factors of STI were amplified with AnyplexTM II STI-7 Detection (V1.1) (Seegene, South Korea). Amplification of nucleic acid was performed Anyplex II HPV28 Detection kit (Seegene, South Korea). HSV type 1-2 were performed Light-Cycler HSV 1/2 Qual Kit (Roche Diagnostics GmbH, Mannheim, Germany). RESULTS: At least one sexually transmitted agent was positive in 49 (54.4%) of the HIV-positive patients. Trichomonas vaginalis, HSV-1 and HSV-2 were not detected in any of the clinical specimens. HPV was found in 31 (%34,4), U. urealyticum in 20 (22.2%), U. parvum in 15 (16.6%), M. genitalium in 8 (8.8%), , M. hominis in 8 (8.8%), N. gonorrhoeae in 5 (5.5%) and C. trachomatis in 2 (2.2%). CONCLUSION: Approximately 55% of HIV (+) individuals without any sexually transmitted disease were found to have one or more non-HIV sexually transmitted agents positive. More than one human papillomavirus serotypes were detected in 35% of these patients. HPV positive patients were referred to the clinic for follow up.