Quality Control Studies on Matricariae Flos
Project no. 20385 · Status: Kapanmış (Yayın bekleniyor) · 2019
Summary
Matricaria recutita (L.) is a plant used in folk medicine since ancient times in the world and Turkey. M. recutita takes place in 26 Pharmacopoeias and Monographs, especially in Turkish Pharmacopoeia. Asteraceae (Compositae) belongs to the family in our country known as medicinal chamomile plant in Europe and West Asia origin, is a member of the daisy family. In addition to the ethnobotanical use, M. recutita is an antiinflammatory, antitumor, antispasmolytic, antiulcer, chemoprotective, antiseptic, antibacterial, antifungal, antiviral, immunostimulant, antimicrobial, antihyperglycemic, sedative, antipuritic, antigenotoxicant, antioxidant and anticancer effect. In this research, three different medicinal chamomile specimens were collected from the natural environment in the Urla district of Izmir. The properties of M. recutita were determined macroscopically and microscopically. Loss of total ash and sulphate ash were determined in the drying period. The samples were analyzed according to the Turkish Pharmacopoeia (2017) and European Pharmacopoeia (8.0) and the results were found to be consistent with the stated values. Water extracts of Matricariae flos were prepared and experiments were carried out by preparing 1 mg / ml concentration solution with water. Total phenolic content, total flavonoids analysis, ABTS+ Radical Cation Trapping Activity and DPPH Radical Trapping Activity were determined on the water extracts obtained from the samples and antioxidant activity was determined. Total phenolic content, total flavonoid analysis results and ABTS+ Radical Cation Capture Activity and DPPH Radical Capture Activity results were consistent. DPPH trapping activity showed very close values in all samples. The indicated values show strong antioxidant activity. ABTS Radical Cation Trapping Activity was the lowest T sample. As a result we can say that the collected drugs and the purchased drugs are samples with antioxidant properties