COMPARISON OF DIFFERENT DIETARY METHODS ON BODY COMPOSITION AND INSULIN, LEPTIN, GHRELIN HORMONES IN OVERWEIGHT WOMEN
Project no. 682 · Status: Kapanmış · 2017
Summary
The aim of this study was to compare the effect of similar calorie-restricted intermittent overnight fasting diet and frequent-meal diet on body composition and insulin, leptin and ghrelin hormones in overweight women. A total of 30 people, with a body mass index of ?25 kg / m2, in the age range of 18-55 years, having no known illness affecting the metabolic rate, completed the study. The volunteers were randomly divided into two groups as the overnight fasting dietary group (GADG) and the dietary group (DG). Diet lists of the two groups were formed with the same calorie restriction (20%). While The DG was administered to six mealtimes, the GADG was administered 5 mealtimes and at least 12 hours overnight fasting for 4 weeks. Some parameters in blood about general health, blood lipids, anemia, menopause were evaluated before the diet; about metabolic rate and fat metabolism were measured before and after the diet with body composition (bioelectrical impedance method), resting metabolic rate (gas analyzer), and physical activity level (questionnaire). There was no significant difference resting metabolic rate (kcal), fat - carbohydrate oxidation (gr/min) and respiratory change rate (VCO2/VO2) (p>0.05), while dietary programs showed similar significant improvement in body composition in both groups (p<0.05). Glucose and insulin levels in GADG and insulin level and insulin resistance index in DG were significantly decreased (p<0.05). There was a significant decrease in leptin level and a significant increase in ghrelin level in GADG, but only a significant increase in ghrelin level was observed in DG (p<0.05). After a monthly application of same calorie-restricted frequent-meal diet and the intermittent diet with a 12 hour- overnight fasting, similar improvements in body composition and insulin, leptin, and ghrelin hormones have been achieved. Keywords: obesity; fat tissue; intermittent diet with overnight fasting; frequent meals