Impact Of Flushing With Aseptic Non-Touch Technique Using Pre-Filled Flush Or Manually Prepared Syringes On Central Venous Catheter Occlusion And Bloodstream Infections In Pediatric Hemato-Oncology Patients: A Randomized Controlled Study
Project no. 849 · Status: Kapanmış · 2016
Summary
Purpose: To compare standardized flushing methods using aseptic non-touch technique; (1) Manually prepared syringes (2) Single-use prefilled flushing devices. Methods: Forty-eight PHO patients with Hickman or Port catheters were recruited to participate in a prospective, randomized study. Standardized flushing methods with aseptic non-touch technique (ANTT) using single-use pre-filled flush syringes (intervention group) or manually prepared syringes (control group) also included the pulsatile technique, use of 10-mL syringe size with 0.9% NaCl for flushing, flushing once a day, flushing training of the nurses. The effects of standardized flushing methods on occlusion and CLABSI evaluated. Results: Of the patients in the intervention group, 8.7% (n: 2) had catheter occlusion, while this rate was 20.0% (n: 5) in the control group. Of the patients in the intervention group, 8.7% (n: 2) had CLABSI, while this rate was 36.0% (n: 9) in the control group. While there was no difference in occlusion, there was a difference between the groups in terms of CLABSI development. In the intervention group, CLABSI rate was 1.9/1000 per catheter-days, in the control group CLABSI rate was 10.1/1000 per catheter-days. In the intervention group, occlusion rate was 1.9/1000 per catheter-days, in the control group, occlusion rate was 5.6/1000 per catheter-days. Conclusion: Standardized flushing and single-use prefilled flush syringes are effective in reducing CLABSI rates in PHO patients. Keywords: central venous catheter, pediatric hemato-oncology, flushing, single-use prefilled flushing devices, aseptic non-touch technique, CLABSI, occlusion.