DETERMINATION OF ESSENTIAL OIL COMPONENTS AND ANTIOXIDANT ACTIVITY OF VERBASCUM PARVİFLORUM LAM.
Project no. 282 · Status: Kapanmış · 2017
Summary
Verbascum species, which have approximately 360 species worldwide, are the largest genus of Scrophulariaceae family. The genus Verbascum, commonly known as “mullein”, which spread to many species, is used for expectorant, mucolytic and wound healing effects as well as in the treatment of rheumatism and hemorrhoids in the folk medicine. Verbascum parviflorum is an endemic species in Western Anatolia. In the present study, we obtained essential oil from this plant, collected from Güme mountain in Tire/Izmir, with Clevenger (water vapor distillation) device and analyzed this essential oil by GC/MS. A total of 23 molecules were identified and ?-terpineol was the major compound. Then, antioxidant activity was determined by DPPH, metal chelating and CUPRAC methods in methanol extract obtained from the plant. In the experiments carried out by DPPH and CUPRAC methods, IC50 values were; 65.2 ± 072 and 38.46 ± 055 µg/mL, respectively. The percent inhibition value was found to be 12.8 ± 27 in metal chelating assay. As a result, it was determined that this species, which is grown endemically in our country, has low yield essential oil and moderate antioxidant activity.