In vitro comparison of ion releases at different pH values in mini implants used with force application in mouth and in as recieved mini implants
Project no. 22320 · Status: Kapanmış (Yayın bekleniyor) · 2021
Summary
<p><strong>Aim: </strong>The aim of this study was to compare the long-term ion release amounts and surface topography of retrieved and as received orthodontic mini-implants in different acidity environments and to evaluate the reusability of mini-implants.</p><p><strong>Method: </strong>In the study, 30 mini-implants pre-used with orthodontic force loading in human mouth and 30 as received (new) mini-implants were used. Artificial saliva solutions with a pH of 2 and pH of 7 were prepared by taking the modified Fusayama solution as guide. Mini-implants were placed in these solutions in separate glass tubes. The tubes were then kept in an incubator at a constant temperature of 37 °C. At the end of 30th, 60th and 180th days, samples were taken from the solutions and the amount of dissolved titanium, aluminum and vanadium ions were determined by an ICP-MS device. After the analyses of the solutions, the surface topographies of the tested mini-implants were evaluated with SEM and SPM devices.</p><p><strong>Results: </strong>Interaction and significance level (p) was accepted as 0.05 in the analyses. Only in the groups; pH of 2 V, (p<0.001) pH of 2 Ti (p<0.001) and pH of 7 V (p=0.01) as received mini-implants released more ions than retrieved mini-implants. No relationship was found between the use of mini-implants and the resulting ion release in other groups. In this study it was revealed that the amount of corrosion occurring in the retrieved mini-implants was not higher than the as received ones. The amount of ions detected in the solutions with a pH of 2 was higher than in the solutions with a pH of 7 (p<0.05). For all groups a valid relationship between the amount of ion release and time could not be established. When SEM images were evaluated, it was observed that there are abrasions and integuments of different shapes and sizes on the surface of the retrieved mini-implants. When the SPM images are evaluated, it is observed that the examined mini implant surfaces become more indented as the acidity level increased. The surfaces of as received mini-implants were relatively flat and had smaller and fewer attachments on their surfaces.</p><p><strong>Conclusion: </strong>It was determined that the amount of dissolution occurred in retrieved mini-implants was not higher than occurred in as received ones. According to the results of the study carried out under laboratory conditions, the reuse of retrieved mini-</p><p>implants does not pose an additional problem when only the amount of ion release and its local and systemic effects are considered. On the other hand, it should be taken into consideration that micro and macro changes on the surface of retrieved mini-implants may adversely affect the application and function of mini-implants. The amount of ion release occurring in the medium with low pH values was found significantly higher than in the medium with relatively higher pH value. For this reason, dental mini- implants should be used carefully in patients with low intraoral pH levels and it should be bared in mind that side effects such as allergic reaction, local and systemic toxicity that these appliances cause may intensify.</p><p><strong>Keywords</strong>; Saliva, Artificial; Orthodontic Anchorage Procedures; Microscopy, Electron, Scanning; Hydrogen-Ion Concentration; Dental Implants; Mass Spectrometry</p>