Magnetic resonance imaging - Based Tumor Segmentation and 3D Printing Modeling for the Surgical Planning of Breast Cancer

Project no. 26347 · Status: Kapanmış (Yayın bekleniyor) · 2023

Summary

<p>This&nbsp;study&nbsp;aimed&nbsp;to&nbsp;create&nbsp;patient-based&nbsp;three-dimensional&nbsp;(3D)&nbsp;breast&nbsp;and&nbsp;tumor&nbsp;models&nbsp;using&nbsp;breast&nbsp;magnetic&nbsp;resonance&nbsp;imaging&nbsp;(MRI)&nbsp;data&nbsp;and&nbsp;to&nbsp;evaluate&nbsp;their&nbsp;use&nbsp;in&nbsp;preoperative&nbsp;planning.&nbsp;10&nbsp;patients&nbsp;diagnosed&nbsp;with&nbsp;breast&nbsp;cancer&nbsp;were&nbsp;included&nbsp;in&nbsp;the&nbsp;study.&nbsp;Preoperative&nbsp;breast&nbsp;MRI&nbsp;examinations&nbsp;of&nbsp;all&nbsp;patients&nbsp;were&nbsp;evaluated.&nbsp;Images&nbsp;were&nbsp;obtained&nbsp;from&nbsp;1.5&nbsp;Tesla&nbsp;and&nbsp;3&nbsp;Tesla&nbsp;MRI.&nbsp;Tumor&nbsp;segmentation&nbsp;was&nbsp;performed&nbsp;from&nbsp;DICOM&nbsp;images.&nbsp;The&nbsp;images&nbsp;were&nbsp;converted&nbsp;to&nbsp;STL&nbsp;format,&nbsp;and&nbsp;full-size&nbsp;breast&nbsp;and&nbsp;tumor&nbsp;models&nbsp;were&nbsp;produced&nbsp;using&nbsp;a&nbsp;3D&nbsp;printer.&nbsp;The&nbsp;prepared&nbsp;models&nbsp;were&nbsp;evaluated&nbsp;by&nbsp;the&nbsp;surgical&nbsp;team&nbsp;before&nbsp;and&nbsp;during&nbsp;surgery.&nbsp;Histopathological&nbsp;results&nbsp;revealed&nbsp;invasive&nbsp;ductal&nbsp;carcinoma&nbsp;in&nbsp;5&nbsp;patients,&nbsp;invasive&nbsp;5&nbsp;ductal&nbsp;carcinoma&nbsp;with&nbsp;ductal&nbsp;carcinoma&nbsp;in&nbsp;situ&nbsp;component&nbsp;in&nbsp;2&nbsp;patients,&nbsp;invasive&nbsp;lobular&nbsp;carcinoma&nbsp;in&nbsp;2&nbsp;patients,&nbsp;and&nbsp;invasive&nbsp;cribrifom&nbsp;carcinoma&nbsp;in&nbsp;1&nbsp;patient.&nbsp;In&nbsp;all&nbsp;cases,&nbsp;the&nbsp;lesions&nbsp;were&nbsp;excised&nbsp;at&nbsp;the&nbsp;correct&nbsp;localization.&nbsp;Only&nbsp;in&nbsp;one&nbsp;patient&nbsp;was&nbsp;a&nbsp;surgical&nbsp;margin&nbsp;of&nbsp;approximately&nbsp;0.1&nbsp;cm&nbsp;due&nbsp;to&nbsp;a&nbsp;superficially&nbsp;located&nbsp;lesion&nbsp;close&nbsp;to&nbsp;the&nbsp;skin.&nbsp;In&nbsp;all&nbsp;other&nbsp;patients,&nbsp;the&nbsp;surgical&nbsp;margins&nbsp;were&nbsp;adequate.&nbsp;Breast&nbsp;MRI-based&nbsp;3D&nbsp;modeling&nbsp;facilitates&nbsp;surgical&nbsp;planning,&nbsp;especially&nbsp;in&nbsp;non-palpable&nbsp;lesions,&nbsp;and&nbsp;is&nbsp;a&nbsp;method&nbsp;that&nbsp;can&nbsp;be&nbsp;added&nbsp;to&nbsp;routine&nbsp;practice.&nbsp;Keywords:&nbsp;Breast&nbsp;cancer,&nbsp;breast&nbsp;MRI,&nbsp;3D&nbsp;modeling,&nbsp;3D&nbsp;printer,&nbsp;surgical&nbsp;planning</p>

View details