The assessment of yearly changes in isokinetic muscle strength and factors affecting prognosis in patients with postpolio syndrome
Project no. 156 · Status: Kapanmış · 2018
Summary
Poliomiyelitis was, in the past, until widespread vaccination programs were successful, one of the most common viral infections that affected children and caused paralytic disease and disability. Some patients with polio sequelae may develop postpolio syndrome years after the original infection, which presents itself with increased weakness, pain and fatigue. Follow-up of postpolio patients with manuel muscle strength measurements are usually insufficient, isokinetik muscle strenght measurements are more sensitive and may help in the early detection of new onset muscle weakness. For this reason, in this study, we aimed to follow up patients with postpolio syndrome for one year with isokinetic measurements, and to detect any change in their strenght, as well as to compare measurements with healthy controls. We included in the study, patients diagnosed as having postpolio syndrome and who were between 30-60 years of age. We measured subjects’ lower extremity isokinetic muscle strenght at baseline and after one year, and compared these results with healthy controls. We were able to include 25 postpolio patients and 15 healthy age matched controls, enrollment was slowed down due to the Covid 19 pandemic. NO change in muscle strenth was detected after one year, in either group. In conclusion, postpolio patients showed no decrease in isokinetic muscle strength after one year, compared to healthy controls. But there is still need for larger scale studies with longer follow-up durations.