Corrosion Rate Analysis of Magnesium Based Biodegradable Metallic Implants In-Vitro Environment
Project no. 704 · Status: Kapanmış · 2015
Summary
Biodegradable implants have many advantages over conventional steel and titanium based implants. Most important of these is the ability of these implants to degrade within a desired span of time (compatible with tissue and bone growth) after their function is over, without giving any harm to the body. The aim of this study is to develop a magnesium based biodegradable implant to be used as a bone plate. Mechanical and physical properties of Mg alloys that should possess for these applications are almost completely established, whereas the applicability still has to be investigated. In this study, Mg based alloys produced with using mechanical alloying and hot pressing. Biodegradability of Mg based alloys was tested as in-vitro in SBF solution. SBF (simulated body fluid) is nearly equal to human body blood plasma with ion concentrations. Seven implants were produced. They were placed in SBF solution and then their corrosion resistances were followed. During the process, visual changes of the implants were observed, pH, Mg ion concentrations of SBF solutions and mass, dimensional changes of degraded implants in solutions were measured. As soon as, implants were placed in SBF solutions, gas outlet of H2 was observed, because of Redox reaction, which took place between implants and SBF. The composites in SBF remained between 1-360 hours and Zn% 2.35 and 3.10 had the longest degradation time when compared to others. Therefore only three of the alloys Zn% 0 (1h), 2.35 (360h) and 3.10 (192h) were selected for the further tests, SEM and mechanical control tests. Keywords: Magnesium, Zinc, Mechanical alloying, biodegradable implant, SBF.