COMPARISON OF OVER RESERVES, MENSTRUAL DISORDERS, PELVIC FLOOR MUSCLE STRENGTH AND BLOOD GHRELIN AND LEPTIN LEVELS IN WOMEN DOING VIGOROUS EXERCISE
Project no. 139 · Status: Kapanmış · 2018
Summary
Aim: We aimed to explore menstrual irregularity rates in women who are professional basketball and volleyball players and compare with non-athlete controls, and investigate it's relation with leptin, ghrelin and Anti-Müllerian Hormone (AMH). Methods: Forty-one professional female athletes and forty-one non-athlete controls aged 18-35 years participated in the study. Fasted whole blood counts, lipid profiles, glucose, hemoglobin A1c, insulin, follicle-stimulating hormone, luteinizing hormone, estradiol, thyroid-stimulating hormone, free thyroxine, free tri-iodothyronine, prolactin, progesterone, testosterone, dehydroepiandrosterone sulfate, cortisol, leptin, ghrelin, AMH, vitamin B12, folate, iron, ferritin, aspartate aminotransferase, alanin aminotransferase, creatine kinase, alkaline phosphatase, lactate dehydrogenase levels obtained after one day of rest and menstrual function states were evaluated. Results: Menstrual irregularities were found in %41 (n = 17) of female athletes and in %24 (n = 10) of non-athlete controls. Ghrelin, leptin, AMH levels were similar in athletes and control group (p > 0.05). While athletes with menstrual irregularities tend to have lower ghrelin and leptin levels and higher AMH than athletes without irregularities, there difference was not statistically significant (p > 0.05). In addition, no significant difference was found between the groups in terms of endocrine and other metabolic parameters (p > 0.05). Conclusions: Our findings support that sports participation may increase the risk of menstrual irregularities. Based on the findings, this effect may be less if the sport does not cause negative energy balance. We can argue that the level of AMH can be used as a marker in the diagnosis and follow-up of athletes with menstrual irregularities.