Evaluation Of The Effect Of Two Different Bioactive Materials On The Success Of Vital Pulp Therapy In Permanent Teeth: A Prospective Clinical Study

Project no. 32695 · Status: Kapanmış (Yayın bekleniyor) · 2024

Summary

<p>Objective:&nbsp;The&nbsp;aim&nbsp;of&nbsp;this&nbsp;prospective&nbsp;randomized&nbsp;clinical&nbsp;study&nbsp;was&nbsp;to&nbsp;evaluate&nbsp;and&nbsp;compare&nbsp;the&nbsp;clinical&nbsp;and&nbsp;radiographic&nbsp;success,&nbsp;as&nbsp;well&nbsp;as&nbsp;postoperative&nbsp;pain&nbsp;levels,&nbsp;following&nbsp;direct&nbsp;pulp&nbsp;capping&nbsp;using&nbsp;two&nbsp;different&nbsp;calcium&nbsp;silicate–based&nbsp;bioactive&nbsp;materials,&nbsp;ProRoot&nbsp;MTA&nbsp;and&nbsp;BIOfactor&nbsp;MTA,&nbsp;in&nbsp;permanent&nbsp;molar&nbsp;teeth&nbsp;with&nbsp;caries-induced&nbsp;pulp&nbsp;exposure.</p><p>Materials&nbsp;and&nbsp;Methods:&nbsp;A&nbsp;total&nbsp;of&nbsp;80&nbsp;patients&nbsp;presenting&nbsp;with&nbsp;deep&nbsp;carious&nbsp;lesions&nbsp;and&nbsp;vital&nbsp;pulp&nbsp;exposure&nbsp;in&nbsp;permanent&nbsp;molar&nbsp;teeth&nbsp;were&nbsp;included&nbsp;in&nbsp;this&nbsp;study.&nbsp;Patients&nbsp;randomly&nbsp;assigned&nbsp;into&nbsp;two&nbsp;groups&nbsp;(n=40&nbsp;each).&nbsp;Following&nbsp;standardized&nbsp;clinical&nbsp;procedures,&nbsp;hemostasis&nbsp;was&nbsp;achieved&nbsp;prior&nbsp;to&nbsp;the&nbsp;direct&nbsp;pulp&nbsp;capping&nbsp;procedure.&nbsp;Direct&nbsp;pulp&nbsp;capping&nbsp;was&nbsp;then&nbsp;performed&nbsp;using&nbsp;either&nbsp;ProRoot&nbsp;MTA&nbsp;or&nbsp;BIOfactor&nbsp;MTA.&nbsp;After&nbsp;placement&nbsp;of&nbsp;the&nbsp;capping&nbsp;material,&nbsp;teeth&nbsp;were&nbsp;temporarily&nbsp;restored,&nbsp;and&nbsp;definitive&nbsp;coronal&nbsp;restorations&nbsp;were&nbsp;completed&nbsp;in&nbsp;a&nbsp;subsequent&nbsp;session.&nbsp;Postoperative&nbsp;pain&nbsp;was&nbsp;assessed&nbsp;using&nbsp;a&nbsp;numerical&nbsp;rating&nbsp;scale&nbsp;(NRS)&nbsp;at&nbsp;predetermined&nbsp;time&nbsp;intervals.&nbsp;Clinical&nbsp;and&nbsp;radiographic&nbsp;evaluations&nbsp;were&nbsp;performed&nbsp;during&nbsp;follow-up&nbsp;periods&nbsp;up&nbsp;to&nbsp;12&nbsp;months.&nbsp;Pulpal&nbsp;area&nbsp;changes&nbsp;were&nbsp;assessed&nbsp;radiographically.&nbsp;Statistical&nbsp;analyses&nbsp;were&nbsp;conducted,&nbsp;and&nbsp;the&nbsp;level&nbsp;of&nbsp;significance&nbsp;was&nbsp;set&nbsp;at&nbsp;p&lt;0.05.</p><p>Results:&nbsp;At&nbsp;the&nbsp;12-month&nbsp;follow-up,&nbsp;both&nbsp;groups&nbsp;demonstrated&nbsp;high&nbsp;clinical&nbsp;success&nbsp;rates&nbsp;(97.5%),&nbsp;with&nbsp;no&nbsp;statistically&nbsp;significant&nbsp;difference&nbsp;between&nbsp;the&nbsp;materials&nbsp;(p&gt;0.05).&nbsp;Postoperative&nbsp;pain&nbsp;levels&nbsp;were&nbsp;similar&nbsp;between&nbsp;the&nbsp;groups&nbsp;at&nbsp;all&nbsp;evaluated&nbsp;time&nbsp;points,&nbsp;with&nbsp;no&nbsp;significant&nbsp;differences&nbsp;observed&nbsp;(p&gt;0.05).&nbsp;Pain&nbsp;scores&nbsp;peaked&nbsp;at&nbsp;6&nbsp;hours&nbsp;postoperatively&nbsp;and&nbsp;decreased&nbsp;over&nbsp;time.&nbsp;A&nbsp;statistically&nbsp;significant&nbsp;reduction&nbsp;in&nbsp;pulpal&nbsp;area&nbsp;was&nbsp;observed&nbsp;in&nbsp;both&nbsp;groups;&nbsp;however,&nbsp;no&nbsp;significant&nbsp;difference&nbsp;was&nbsp;found&nbsp;between&nbsp;the&nbsp;materials&nbsp;(p=0.914).&nbsp;Additionally,&nbsp;demographic&nbsp;and&nbsp;clinical&nbsp;variables,&nbsp;including&nbsp;age,&nbsp;gender,&nbsp;exposure&nbsp;size,&nbsp;exposure&nbsp;site,&nbsp;number&nbsp;of&nbsp;exposures,&nbsp;and&nbsp;hemostasis&nbsp;time,&nbsp;showed&nbsp;no&nbsp;significant&nbsp;effect&nbsp;on&nbsp;treatment&nbsp;outcomes.</p><p>Conclusion:&nbsp;Both&nbsp;ProRoot&nbsp;MTA&nbsp;and&nbsp;BIOfactor&nbsp;MTA&nbsp;demonstrated&nbsp;comparable&nbsp;clinical&nbsp;and&nbsp;radiographic&nbsp;success&nbsp;in&nbsp;direct&nbsp;pulp&nbsp;capping&nbsp;procedures.&nbsp;BIOfactor&nbsp;MTA&nbsp;can&nbsp;be&nbsp;considered&nbsp;a&nbsp;reliable&nbsp;alternative&nbsp;to&nbsp;ProRoot&nbsp;MTA&nbsp;in&nbsp;vital&nbsp;pulp&nbsp;therapy.</p><p></p>

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