Examination of model membrane systems with theoretical, experimental and image processing techniques
Project no. 23217 · Status: Kapanmış (Yayın bekleniyor) · 2022
Summary
<p>Due to their complex structures, working with biological membranes is quite challenging. As an alternative to studying biological membranes, model membranes, which possess nearly identical properties but allow for controlled manipulation of component types and concentrations, are frequently utilized. This approach facilitates a clearer understanding of the effects of agents on membranes. The molecular-level effects and interactions of agents with model membranes can be determined through experiments conducted in laboratories using various techniques. Furthermore, theoretical calculations of these effects and interactions can be performed using molecular dynamics software. In addition to these two methods, model membrane structures can also be analyzed using image processing techniques facilitated by computer software. The images analyzed are obtained through multiple microscopic imaging methods. This enables the interaction of several drugs, at different concentrations, with model membranes to be visualized and analyzed through various approaches.</p><p>In this project study, the effects of selected agents on model membranes were investigated by employing a combination of experimental, theoretical, and image processing methods, depending on varying concentrations. As a result of these analyses, significant insights were obtained to enhance the understanding of potential effects and interactions within model membrane systems.</p>