Activities of Linezolid against nontuberculous mycobacteria.
Makaleler > Tam Makale · 2007
Yazarlar: Cengiz ÇAVUŞOĞLU, Ilknur Soyler, Pinar Akinci
The new microbiologica, Uluslararası, 2007, cilt 30, ss 411-4
Özet
The activity of linezolid (Pfizer, USA) was tested by broth microdilution against 53 clinical isolates of non-tuberculous mycobacteria (NTM), including the common disease producing species Mycobacterium avium, M. intracellulare, M. fortuitum, M. chelonae and M. abscessus, obtained from western Turkey. The isolates of M. abscessus and M. intracellulare were the least susceptible, M. mucogenicum, M. gordonae and M. avium were the most susceptible to linezolid of the common species of NTM. Linezolid showed a variable sensitivity in all strains; therefore, each species and strain must be individually evaluated, and it is always advisable to perform in vitro sensitivity tests before using the drug for human therapy.