Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma
Makaleler > Tam Makale · 2012
Yazarlar: Seckin Cagirgani, Nur SOYER, Filiz VURAL, Güray SAYDAM, Ilgın YILDIRIM ŞİMŞİR, Ayhan DÖNMEZ, Taner AKALIN, Selen BAYRAKTAROĞLU, Murat TOMBULOĞLU
Turkish Journal of Hematology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2012, cilt 29, ss 397-400
Özet
UNLABELLED: Both leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytoclastic vasculitis. After 3 courses of standarddose chemotherapy all skin and pulmonary lesions disappeared. Autologous peripheral stem cell transplantation was performed and during 1 year of follow-up the patient was in complete remission; after 1 year, laboratory test results indicated disease relapse. Although the patient was treated with bortezomib and dexamethasone, the disease progressed. Non-myeloablative allogeneic stem cell transplantation was performed, but despite of all treatment the patient died due to disease progression. CONFLICT OF INTEREST: None declared.