Gingival crevicular fluid monocyte chemoattractant protein-1 and RANTES levels in patients with generalized aggressive periodontitis
Makaleler > Tam Makale · 2004
Yazarlar: Gülnur EMİNGİL, FATMA GÜL ATİLLA, Afig BERDELİ
JOURNAL OF CLINICAL PERIODONTOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2004, cilt 31, ss 829-834
DOI: 10.1111/j.1600-051x.2004.00584.x
Özet
Background: Local and systemic inflammatory and immune mechanisms may be implicated in the pathogenesis of the aggressive forms of periodontal disease. Chemokines, monocyte chemoattractant protein-1 (MCP-1) and regulated on activation, normal T cells expressed and secreted RANTES (regulated on activation, normal T cells expressed and secreted), are involved in the activation and recruitment of inflammatory and immune cells to the infected sites and thereby mediating a variety of pathophysiological conditions. The aim of the present study was to examine the gingival crevicular fluid (GCF) levels of MCP-1 and RANTES in patients with generalized agressive periodontitis (G-AgP).